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We introduce LearnAD, a neuro-symbolic method for predicting Alzheimer's disease from brain magnetic resonance imaging data, learning fully interpretable rules. LearnAD applies statistical models, Decision Trees, Random Forests, or GNNs to…

Machine Learning · Computer Science 2026-01-06 Thomas Andrews , Mark Law , Sara Ahmadi-Abhari , Alessandra Russo

Alzheimer's disease (AD) has a complex and multifactorial etiology, which requires integrating information about neuroanatomy, genetics, and cerebrospinal fluid biomarkers for accurate diagnosis. Hence, recent deep learning approaches…

Machine Learning · Computer Science 2023-03-15 Tom Nuno Wolf , Sebastian Pölsterl , Christian Wachinger

Inspired by foveal vision, hard attention models promise interpretability and parameter economy. However, existing models like the Recurrent Model of Visual Attention (RAM) and Deep Recurrent Attention Model (DRAM) failed to model the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Pengcheng Pan , Yonekura Shogo , Yasuo Kuniyoshi

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…

Image and Video Processing · Electrical Eng. & Systems 2024-03-11 Maleka Khatun , Md Manowarul Islam , Habibur Rahman Rifat , Md. Shamim Bin Shahid , Md. Alamin Talukder , Md Ashraf Uddin

Background: Alzheimers disease is a progressive neurodegenerative disorder and the main cause of dementia in aging. Hippocampus is prone to changes in the early stages of Alzheimers disease. Detection and observation of the hippocampus…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Hossein Yousefi-Banaem , Saber Malekzadeh

Neuroimaging of large populations is valuable to identify factors that promote or resist brain disease, and to assist diagnosis, subtyping, and prognosis. Data-driven models such as convolutional neural networks (CNNs) have increasingly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Nikhil J. Dhinagar , Sophia I. Thomopoulos , Emily Laltoo , Paul M. Thompson

Developing successful artificial intelligence systems in practice depends on both robust deep learning models and large, high-quality data. However, acquiring and labeling data can be prohibitively expensive and time-consuming in many…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Saba Dadsetan , Mohsen Hejrati , Shandong Wu , Somaye Hashemifar

Early diagnosis of Alzheimer's disease and its prodromal stage, also known as mild cognitive impairment (MCI), is critical since some patients with progressive MCI will develop the disease. We propose a multi-stream deep convolutional…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Mona Ashtari-Majlan , Abbas Seifi , Mohammad Mahdi Dehshibi

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Quantitative Methods · Quantitative Biology 2020-10-07 Sema Candemir , Xuan V. Nguyen , Luciano M. Prevedello , Matthew T. Bigelow , Richard D. White , Barbaros S. Erdal

Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…

Computer Vision and Pattern Recognition · Computer Science 2014-04-29 Fayao Liu , Chunhua Shen

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

Image and Video Processing · Electrical Eng. & Systems 2021-01-07 Kuo Yang , Emad A. Mohammed

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

Signal Processing · Electrical Eng. & Systems 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

Alzheimer's Disease (AD) is the world leading cause of dementia, a progressively impairing condition leading to high hospitalization rates and mortality. To optimize the diagnostic process, numerous efforts have been directed towards the…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Davide Coluzzi , Valentina Bordin , Massimo Walter Rivolta , Igor Fortel , Liang Zhang , Alex Leow , Giuseppe Baselli

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

Machine Learning · Computer Science 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

Machine learning has been increasingly used to obtain individualized neuroimaging signatures for disease diagnosis, prognosis, and response to treatment in neuropsychiatric and neurodegenerative disorders. Therefore, it has contributed to a…

We present an attention-based modular neural framework for computer vision. The framework uses a soft attention mechanism allowing models to be trained with gradient descent. It consists of three modules: a recurrent attention module…

Machine Learning · Computer Science 2016-04-29 Samira Ebrahimi Kahou , Vincent Michalski , Roland Memisevic

Imaging-based early diagnosis of Alzheimer Disease (AD) has become an effective approach, especially by using nuclear medicine imaging techniques such as Positron Emission Topography (PET). In various literature it has been found that PET…

Machine Learning · Computer Science 2021-03-24 Jiaming Guo , Wei Qiu , Xiang Li , Xuandong Zhao , Ning Guo , Quanzheng Li

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning has been a subject of intense research in recent years. Recent success of deep learning in computer vision has progressed such research…

Computer Vision and Pattern Recognition · Computer Science 2019-06-05 Naimul Mefraz Khan , Marcia Hon , Nabila Abraham

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Weichen Huang
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