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We developed THz-resonant scanning probe tips, yielding strongly enhanced and nanoscale confined THz near fields at their tip apex. The tips with length in the order of the THz wavelength ({\lambda} = 96.5 {\mu}m) were fabricated by focused…

Fourier-transform infrared spectroscopy (FTIR) has matured into a versatile technique with relevance for environmental monitoring, pharmaceutical research, and food safety applications. However, compared to other spectroscopic methods, it…

Instrumentation and Detectors · Physics 2024-09-04 Jakub Mnich , Johannes Kunsch , Matthias Budden , Thomas Gebert , Marco Schossig , Jarosław Sotor , Łukasz A. Sterczewski

Magnetic resonance force microscopy (MRFM) is a scanning probe technique capable of detecting MRI signals from nanoscale sample volumes, providing a paradigm-changing potential for structural biology and medical research. Thus far, however,…

Understanding light-matter interaction at the nanoscale requires probing the optical properties of matter at the individual nano-absorber level. To this end, we have developed a nanomechanical photothermal sensing platform that can be used…

Optics · Physics 2024-06-07 Kostas Kanellopulos , Robert G. West , Silvan Schmid

One of the possible ways to maintain the micrometer spatial resolution while performing ion beam analysis in the air is to increase the energy of ions. In order to explore capabilities and limitations of this approach, we have tested a…

Instrumentation and Detectors · Physics 2019-03-13 Milko Jakšić , Davit Chokheli , Stjepko Fazinić , Veljko Grilj , Natko Skukan , Ivan Sudić , Tonči Tadić , Tome Antičić

This article explores the application of various artificial intelligence techniques to the analysis of near-infrared (NIR) spectra of paracetamol, within the spectral range of 900 nm to 1800 nm. The main objective is to evaluate the…

Optics · Physics 2025-10-14 Aminata Sow , Tidiane Diallo

With increasing interest in utilizing nanostructures as nanoscale heat sources, the ability to precisely measure photothermal effects at the nanoscale has become increasingly significant. Techniques based on fluorescence or Raman signals…

Optics · Physics 2025-06-10 Seongmin Im , Wei Hong , Gayatri Chandran , Xing Wang , Yang Zhao

Scattering scanning near-field optical microscopy (s-SNOM) is a technique to enhance the spatial resolution, and when combined by Fourier transform spectroscopy it can provide spectroscopic information with high spatial resolution. This…

Label-free imaging of rapidly moving, sub-diffraction sized structures has important applications in both biology and material science, as it removes the limitations associated with fluorescence tagging. However, unlabeled nanoscale…

The purpose was two-fold: To explore the capability of the Diamond Synchrotron infra-red so as to include near-field photothermal microspectroscopy (PTMS); and Toward a quantitative nanohistology - investigation of scleroderma using…

Instrumentation and Detectors · Physics 2022-06-15 L Bozec , G Cinque , M Reading , H M Pollock

A new method for high-sensitivity subwavelength spectromicroscopy is proposed based on the usage of a spaser (near-field laser) in the form of a scanning probe microscope tip. The high spatial resolution is defined by the tip's curvature,…

Mesoscale and Nanoscale Physics · Physics 2012-08-17 Yuriy E. Lozovik , Igor A. Nechepurenko , Alexander V. Dorofeenko , Alexander A. Pukhov , Eugeniy S. Andrianov

Surface-enhanced Raman spectroscopy (SERS) allows single-molecule detection due to the strong field localization occurring at sharp bends or kinks of the metal-vacuum interface. An important question concerns the limits of the signal…

Optics · Physics 2008-06-19 Sanshui Xiao , Niels Asger Mortensen , Antti-Pekka Jauho

Femtosecond interferometry combined with acousto-optical phase modulation is an effective approach to implement various types of coherent nonlinear and multidimensional spectroscopy schemes. The high sensitivity of this method has recently…

Atomic Physics · Physics 2025-02-24 Friedemann Landmesser , Nicolai Gölz , Ulrich Bangert , Tobias Sixt , Lukas Bruder

We present an imaging technique that allows the recovery of the transparency profile of wavelength-scale objects with deep subwavelength resolution based on far-field intensity measurements. The approach, interscale mixing microscopy (IMM),…

Optics · Physics 2017-03-21 Sandeep Inampudi , Nicholas Kuhta , Viktor A. Podolskiy

Optical nanoscopy is crucial in life and materials sciences, revealing subtle cellular processes and nanomaterial properties. Scattering-type Scanning Near-field Optical Microscopy (s-SNOM) provides nanoscale resolution, relying on the…

Deep-tissue chemical imaging plays a vital role in biological and medical applications. Here, we present a shortwave infrared photothermal (SWIP) microscope for millimeter-deep vibrational imaging with sub-micron lateral resolution and…

Advancement in mid-infrared (MIR) technology has led to promising biomedical applications of MIR spectroscopy, such as liquid biopsy or breath diagnosis. On the contrary, MIR microscopy has been rarely used for live biological samples in an…

Atomic force microscopy (AFM) is a well-known tool for studying surface roughness and to collect depth information about features on the top atomic layer of samples. By combining secondary ion mass spectroscopy (SIMS) with focused ion beam…

Materials Science · Physics 2022-10-18 Lex Pillatsch , Szilvia Kalácska , Xavier Maeder , Johann Michler

The potential of photon detectors to achieve precise timing information is of increasing importance in many domains, PET and CT scanners in medical imaging and particle physics detectors, amongst others. The goal to increase by an order of…

Instrumentation and Detectors · Physics 2021-01-11 S. Enoch , A. Gola , P. Lecoq , A. Rivetti

Infrared (IR) imaging has become a viable tool for visualizing various chemical bonds in a specimen. The performance, however, is limited in terms of spatial resolution and imaging speed. Here, instead of measuring the loss of the IR beam,…

Optics · Physics 2018-11-20 Yeran Bai , Delong Zhang , Lu Lan , Yimin Huang , Kerry Maize , Ali Shakouri , Ji-Xin Cheng
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