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While the strength of Topological Data Analysis has been explored in many studies on high dimensional numeric data, it is still a challenging task to apply it to text. As the primary goal in topological data analysis is to define and…

Machine Learning · Computer Science 2020-03-31 Shafie Gholizadeh , Ketki Savle , Armin Seyeditabari , Wlodek Zadrozny

Complex prediction models such as deep learning are the output from fitting machine learning, neural networks, or AI models to a set of training data. These are now standard tools in science. A key challenge with the current generation of…

Machine Learning · Computer Science 2022-10-21 Meng Liu , Tamal K. Dey , David F. Gleich

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

Neurons and Cognition · Quantitative Biology 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

The application of network techniques to the analysis of neural data has greatly improved our ability to quantify and describe these rich interacting systems. Among many important contributions, networks have proven useful in identifying…

Quantitative Methods · Quantitative Biology 2018-06-14 Ann E. Sizemore , Jennifer Phillips-Cremins , Robert Ghrist , Danielle S. Bassett

Understanding the topological characteristics of data is important to many areas of research. Recent work has demonstrated that synthetic 4D image-type data can be useful to train 4D convolutional neural network models to see topological…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Khalil Mathieu Hannouch , Stephan Chalup

Endothelial cells form the linchpin of vascular and lymphatic systems, creating intricate networks that are pivotal for angiogenesis, controlling vessel permeability, and maintaining tissue homeostasis. Despite their critical roles, there…

Cell Behavior · Quantitative Biology 2026-05-25 Okezue Bell , Anthony Bell

Spatial functional organization is a hallmark of biological brains: neurons are arranged topographically according to their response properties, at multiple scales. In contrast, representations within most machine learning models lack…

Computation and Language · Computer Science 2025-10-22 Taha Binhuraib , Greta Tuckute , Nicholas Blauch

Seeking effective neural networks is a critical and practical field in deep learning. Besides designing the depth, type of convolution, normalization, and nonlinearities, the topological connectivity of neural networks is also important.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Kun Yuan , Quanquan Li , Jing Shao , Junjie Yan

Neural networks encode inputs as high-dimensional vectors, known as representations, that capture how models process data by encoding task-relevant structure and semantics. Representation alignment refers to the degree to which different…

Computational Geometry · Computer Science 2026-05-26 Xinyuan Yan , Rita Sevastjanova , Mennatallah El-Assady , Bei Wang

Medical image segmentation, which aims to automatically extract anatomical or pathological structures, plays a key role in computer-aided diagnosis and disease analysis. Despite the problem has been widely studied, existing methods are…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Han Zhang , Lok Ming Lui

Detecting meaningful structure in neural activity and connectivity data is challenging in the presence of hidden nonlinearities, where traditional eigenvalue-based methods may be misleading. We introduce a novel approach to matrix analysis,…

Neurons and Cognition · Quantitative Biology 2015-11-24 Chad Giusti , Eva Pastalkova , Carina Curto , Vladimir Itskov

A topological shape analysis is proposed and utilized to learn concepts that reflect shape commonalities. Our approach is two-fold: i) a spatial topology analysis of point cloud segment constellations within objects. Therein constellations…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Christian A. Mueller , Andreas Birk

Representation learning on graphs is a fundamental problem that can be crucial in various tasks. Graph neural networks, the dominant approach for graph representation learning, are limited in their representation power. Therefore, it can be…

Machine Learning · Computer Science 2025-01-17 Zuoyu Yan , Qi Zhao , Ze Ye , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

Topological analysis of the magnetic field in simulated plasmas allows the study of various physical phenomena in a wide range of settings. One such application is magnetic reconnection, a phenomenon related to the dynamics of the magnetic…

We present a novel method for characterizing the microstructure of a material from volumetric datasets such as 3D image data from computed tomography (CT). The method is based on a new statistical model for the distribution of voxel…

Materials Science · Physics 2021-01-06 Elise Otterlei Brenne , Vedrana Andersen Dahl , Peter Stanley Jørgensen

Learning graph convolutional networks (GCNs) is an emerging field which aims at generalizing convolutional operations to arbitrary non-regular domains. In particular, GCNs operating on spatial domains show superior performances compared to…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Hichem Sahbi

Rigid body interactions are fundamental to numerous scientific disciplines, but remain challenging to simulate due to their abrupt nonlinear nature and sensitivity to complex, often unknown environmental factors. These challenges call for…

Machine Learning · Computer Science 2025-07-28 Amaury Wei , Olga Fink

Neuropsychiatric disorders impact functional connectivity of the brain at the network level. The identification and statistical testing of disorder-related networks remains challenging. We propose novel methods to streamline the detection…

Applications · Statistics 2017-01-16 Shuo Chen , Yishi Xing , Jian Kang , Dinesh Shukla , Peter Kochunov , L. Elliot Hong

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Characterization of breast parenchyma on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging task owing to the complexity of underlying tissue structures. Current quantitative approaches, including radiomics and…

Quantitative Methods · Quantitative Biology 2021-05-14 Fan Wang , Saarthak Kapse , Steven Liu , Prateek Prasanna , Chao Chen
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