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Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

We consider the problem of finding an accurate representation of neuron shapes, extracting sub-cellular features, and classifying neurons based on neuron shapes. In neuroscience research, the skeleton representation is often used as a…

Computer Vision and Pattern Recognition · Computer Science 2022-12-15 Jiaxiang Jiang , Michael Goebel , Cezar Borba , William Smith , B. S. Manjunath

The context of this paper is the use of formal methods for topology-based geometric modelling. Topology-based geometric modelling deals with objects of various dimensions and shapes. Usually, objects are defined by a graph-based topological…

Graphics · Computer Science 2011-02-15 Thomas Bellet , Agnès Arnould , Pascale Le Gall

Researchers in the field of connectomics are working to reconstruct a map of neural connections in the brain in order to understand at a fundamental level how the brain processes information. Constructing this wiring diagram is done by…

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser

Cytoarchitecture describes the spatial organization of neuronal cells in the brain, including their arrangement into layers and columns with respect to cell density, orientation, or presence of certain cell types. It allows to segregate the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Christian Schiffer , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

Shape graphs are complex geometrical structures commonly found in biological and anatomical systems. A shape graph is a collection of nodes, some connected by curvilinear edges with arbitrary shapes. Their high complexity stems from the…

Computation · Statistics 2024-09-17 Benjamin Beaudett , Anuj Srivastava

Developing automated and semi-automated solutions for reconstructing wiring diagrams of the brain from electron micrographs is important for advancing the field of connectomics. While the ultimate goal is to generate a graph of neuron…

Computer Vision and Pattern Recognition · Computer Science 2016-08-09 William Gray Roncal , Colin Lea , Akira Baruah , Gregory D. Hager

The shape and connectivity of a neuron determine its function. Modern imaging methods have proven successful at extracting such information. However, in order to analyze this type of data, neuronal morphology needs to be encoded in a…

Neurons and Cognition · Quantitative Biology 2019-03-07 Tamal Batabyal , Barry Condron , Scott T. Acton

The increasing ubiquity of smartphones and resurgence of VR/AR techniques, it is expected that our everyday environment may soon be decorating with objects connecting with virtual elements. Alerting to the presence of these objects is…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Liming Xu , Dave Towey , Andrew P. French , Steve Benford

The shapes and morphology of the organs and tissues are important prior knowledge in medical imaging recognition and segmentation. The morphological operation is a well-known method for morphological feature extraction. As the morphological…

Computer Vision and Pattern Recognition · Computer Science 2021-03-09 Chentian Li , Chi Ma , William W. Lu

Nervous systems are characterized by neurons displaying a diversity of morphological shapes. Traditionally, different shapes have been qualitatively described based on visual inspection and quantitatively described based on morphometric…

Neurons and Cognition · Quantitative Biology 2016-03-29 Lida Kanari , Paweł Dłotko , Martina Scolamiero , Ran Levi , Julian Shillcock , Kathryn Hess , Henry Markram

This work describes a novel methodology for automatic contour extraction from 2D images of 3D neurons (e.g. camera lucida images and other types of 2D microscopy). Most contour-based shape analysis methods can not be used to characterize…

Computer Vision and Pattern Recognition · Computer Science 2008-10-24 J. J. G. Leandro , R. M. Cesar , L. da F. Costa

Although deep learning approaches have had tremendous success in image, video and audio processing, computer vision, and speech recognition, their applications to three-dimensional (3D) biomolecular structural data sets have been hindered…

Quantitative Methods · Quantitative Biology 2017-11-01 Zixuan Cang , Guo-Wei Wei

Methods from computational topology are becoming more and more popular in computer vision and have shown to improve the state-of-the-art in several tasks. In this paper, we investigate the applicability of topological descriptors in the…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Matthias Zeppelzauer , Bartosz Zielinski , Mateusz Juda , Markus Seidl

Structural pattern recognition describes and classifies data based on the relationships of features and parts. Topological invariants, like the Euler number, characterize the structure of objects of any dimension. Cohomology can provide…

Computer Vision and Pattern Recognition · Computer Science 2011-07-14 Rocio Gonzalez-Diaz , Adrian Ion , Mabel Iglesias-Ham , Walter G. Kropatsch

Shape analysis and classification are popular methods for biologists, biophysicists and mathematicians investigating relationships between object function and form. Classic shape descriptors, such as sphericity, can be powerful but may be…

Quantitative Methods · Quantitative Biology 2025-02-21 Allyson Quinn Ryan , Johannes Soltwedel , Carl D. Modes

Given a 3D surface defined by an elevation function on a 2D grid as well as non-spatial features observed at each pixel, the problem of surface segmentation aims to classify pixels into contiguous classes based on both non-spatial features…

Computer Vision and Pattern Recognition · Computer Science 2020-08-27 Wenchong He , Arpan Man Sainju , Zhe Jiang , Da Yan

In present paper we discuss several approaches to reconstructing the topology of the physical space from neural activity data of CA1 fields in mice hippocampus, in particular, having Cognitome theory of brain function in mind. In our…

Neurons and Cognition · Quantitative Biology 2022-12-07 Konstantin Sorokin , Anton Ayzenberg , Konstantin Anokhin , Vladimir Sotskov , Maxim Beketov , Andrey Zaitsew , Robert Drynkin

This paper introduces a novel framework called DTNet for 3D mesh reconstruction and generation via Disentangled Topology. Beyond previous works, we learn a topology-aware neural template specific to each input then deform the template to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-13 Ka-Hei Hui , Ruihui Li , Jingyu Hu , Chi-Wing Fu
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