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Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

Neurons and Cognition · Quantitative Biology 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács

The geometry of neurons is known to be important for their functions. Hence, neurons are often classified by their morphology. Two recent methods, persistent homology and the topological morphology descriptor, assign a morphology descriptor…

Neurons and Cognition · Quantitative Biology 2022-04-08 David Beers , Despoina Goniotaki , Diane P. Hanger , Alain Goriely , Heather A. Harrington

Topological data analysis provides a collection of tools to encapsulate and summarize the shape of data. Currently it is mainly restricted to \emph{mapper algorithm} and \emph{persistent homology}. In this paper we introduce new…

Algebraic Topology · Mathematics 2019-01-23 Paweł Dłotko

This paper introduces and demonstrates a computational pipeline for the statistical analysis of shape graph datasets, namely geometric networks embedded in 2D or 3D spaces. Unlike traditional abstract graphs, our purpose is not only to…

Machine Learning · Computer Science 2026-02-19 Murad Hossen , Demetrio Labate , Nicolas Charon

This work is concerned with a representation of shapes that disentangles fine, local and possibly repeating geometry, from global, coarse structures. Achieving such disentanglement leads to two unrelated advantages: i) a significant…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Luca Morreale , Noam Aigerman , Paul Guerrero , Vladimir G. Kim , Niloy J. Mitra

The surge in 3D modeling has led to a pronounced research emphasis on the field of 3D shape retrieval. Numerous contemporary approaches have been put forth to tackle this intricate challenge. Nevertheless, effectively addressing the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Rihao Chang , Yongtao Ma , Tong Hao , Weizhi Nie

Reconstructing the intricate local morphology of neurons and their long-range projecting axons can address many connectivity related questions in neuroscience. The main bottleneck in connectomics pipelines is correcting topological errors,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Anna Grim , Jayaram Chandrashekar , Uygar Sumbul

Reconstructing 3D objects from 2D images is both challenging for our brains and machine learning algorithms. To support this spatial reasoning task, contextual information about the overall shape of an object is critical. However, such…

Computer Vision and Pattern Recognition · Computer Science 2022-09-19 Dominik J. E. Waibel , Scott Atwell , Matthias Meier , Carsten Marr , Bastian Rieck

Digital neuron reconstruction from 3D microscopy images is an essential technique for investigating brain connectomics and neuron morphology. Existing reconstruction frameworks use convolution-based segmentation networks to partition the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Runkai Zhao , Heng Wang , Chaoyi Zhang , Weidong Cai

In many areas of applied geometric/numeric computational mathematics, including geo-mapping, computer vision, computer graphics, finite element analysis, medical imaging, geometric design, and solid modeling, one has to compute incidences,…

Computational Geometry · Computer Science 2019-11-20 Alberto Paoluzzi , Vadim Shapiro , Antonio DiCarlo , Francesco Furiani , Giulio Martella , Giorgio Scorzelli

Segmentations are often necessary for the analysis of image data. They are used to identify different objects, for example cell nuclei, mitochondria, or complete cells in microscopic images. There might be features in the data, that cannot…

Computational Geometry · Computer Science 2016-05-31 Julia Portl , Heike Leitte

Deep learning methods have achieved impressive performance for multi-class medical image segmentation. However, they are limited in their ability to encode topological interactions among different classes (e.g., containment and exclusion).…

Shape reconstruction from imaging volumes is a recurring need in medical image analysis. Common workflows start with a segmentation step, followed by careful post-processing and,finally, ad hoc meshing algorithms. As this sequence can be…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Antonio Pepe , Richard Schussnig , Jianning Li , Christina Gsaxner , Dieter Schmalstieg , Jan Egger

The structural analysis of shape boundaries leads to the characterization of objects as well as to the understanding of shape properties. The literature on graphs and networks have contributed to the structural characterization of shapes…

Computer Vision and Pattern Recognition · Computer Science 2017-11-15 Gisele H. B. Miranda , Jeaneth Machicao , Odemir M. Bruno

Many works in the recent literature introduce semantic mapping methods that use CNNs (Convolutional Neural Networks) to recognize semantic properties in images. The types of properties (eg.: room size, place category, and objects) and their…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Ygor C. N. Sousa , Hansenclever F. Bassani

A recent publication provides the network graph for a neocortical microcircuit comprising 8 million connections between 31,000 neurons (H. Markram, et al., Reconstruction and simulation of neocortical microcircuitry, Cell, 163 (2015) no. 2,…

Neurons and Cognition · Quantitative Biology 2017-06-13 Pawe Dotko , Kathryn Hess , Ran Levi , Max Nolte , Michael Reimann , Martina Scolamiero , Katharine Turner , Eilif Muller , Henry Markram

In many scenarios, especially biomedical applications, the correct delineation of complex fine-scaled structures such as neurons, tissues, and vessels is critical for downstream analysis. Despite the strong predictive power of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Xiaoling Hu

This article discusses how the individual morphological properties of basic objects (e.g. neurons, molecules and aggregates), jointly with their particular spatial distribution, can determine the connectivity and dynamics of systems…

Molecular Networks · Quantitative Biology 2007-05-23 Luciano da Fontoura Costa

Topology is a central concept of mathematics, which allows us to distinguish two isolated rings with linked ones. In material science, researchers discovered topologically different carbon allotropes in a form of a cage, a tube, and a…

Mesoscale and Nanoscale Physics · Physics 2023-04-05 Shinichi Saito , Isao Tomita