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Purpose: Radiologists are tasked with visually scrutinizing large amounts of data produced by 3D volumetric imaging modalities. Small signals can go unnoticed during the 3d search because they are hard to detect in the visual periphery.…

Human-Computer Interaction · Computer Science 2024-05-02 Devi Klein , Srijita Karmakar , Aditya Jonnalagadda , Craig K. Abbey , Miguel P. Eckstein

Reconstructing 3D cone beam computed tomography (CBCT) images from a limited set of projections is an important inverse problem in many imaging applications from medicine to inertial confinement fusion (ICF). The performance of traditional…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Xiaojian Xu , Marc Klasky , Michael T. McCann , Jason Hu , Jeffrey A. Fessler

In recent years, diverging-wave (DW) ultrasound imaging has become a very promising methodology for cardiovascular imaging due to its high temporal resolution. However, if they are limited in number, DW transmits provide lower image quality…

Image and Video Processing · Electrical Eng. & Systems 2020-03-25 Jingfeng Lu , Fabien Millioz , Damien Garcia , Sebastien Salles , Wanyu Liu , Denis Friboulet

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies

This paper describes the mathematical structure of the ill-posed nonlinear inverse problem of low-dose dental cone-beam computed tomography (CBCT) and explains the advantages of a deep learning-based approach to the reconstruction of…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Hyoung Suk Park , Chang Min Hyun , Jin Keun Seo

We present an effective post-processing method to reduce the artifacts from sparsely reconstructed cone-beam CT (CBCT) images. The proposed method is based on the state-of-the-art, image-to-image generative models with a perceptual loss as…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Haofu Liao , Zhimin Huo , William J. Sehnert , Shaohua Kevin Zhou , Jiebo Luo

An approach to incorporate deep learning within an iterative image reconstruction framework to reconstruct images from severely incomplete measurement data is presented. Specifically, we utilize a convolutional neural network (CNN) as a…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Brendan Kelly , Thomas P. Matthews , Mark A. Anastasio

By the ALARA (As Low As Reasonably Achievable) principle, ultra-low-dose CT reconstruction is a holy grail to minimize cancer risks and genetic damages, especially for children. With the development of medical CT technologies, the iterative…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Weiwen Wu , Chuang Niu , Shadi Ebrahimian , Hengyong Yu , Mannu Kalra , Ge Wang

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

Computed tomography is widely used as an imaging tool to visualize three-dimensional structures with expressive bone-soft tissue contrast. However, CT resolution and radiation dose are tightly entangled, highlighting the importance of…

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

Image guidance for minimally invasive interventions is usually performed by acquiring fluoroscopic images using a C-arm system. However, the projective data provide only limited information about the spatial structure and position of…

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Cone beam computed tomography (CBCT) has been widely used in clinical practice, especially in dental clinics, while the radiation dose of X-rays when capturing has been a long concern in CBCT imaging. Several research works have been…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Yu Fang , Lanzhuju Mei , Changjian Li , Yuan Liu , Wenping Wang , Zhiming Cui , Dinggang Shen

Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sadanand Singh , Thomas Paul Matthews , Meet Shah , Brent Mombourquette , Trevor Tsue , Aaron Long , Ranya Almohsen , Stefano Pedemonte , Jason Su

Breast cancer is the second most common type of cancer in women in Canada and the United States, representing over 25\% of all new female cancer cases. As such, there has been immense research and progress on improving screening and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Chi-en Amy Tai , Hayden Gunraj , Nedim Hodzic , Nic Flanagan , Ali Sabri , Alexander Wong

X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical concern in most image guided radiation therapy procedures. It is the goal of this paper to develop a fast GPU-based algorithm to reconstruct high quality CBCT images…

Medical Physics · Physics 2015-05-19 Xun Jia , Bin Dong , Yifei Lou , Steve B. Jiang

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

Early detection of breast cancer through screening mammography yields a 20-35% increase in survival rate; however, there are not enough radiologists to serve the growing population of women seeking screening mammography. Although commercial…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Stefano Pedemonte , Brent Mombourquette , Alexis Goh , Trevor Tsue , Aaron Long , Sadanand Singh , Thomas Paul Matthews , Meet Shah , Jason Su

Background and Aim: Recently, deep learning using convolutional neural network has been used successfully to classify the images of breast cells accurately. However, the accuracy of manual classification of those histopathological images is…

Image and Video Processing · Electrical Eng. & Systems 2021-08-11 Ashu Thapa , Abeer Alsadoon , P. W. C. Prasad , Simi Bajaj , Omar Hisham Alsadoon , Tarik A. Rashid , Rasha S. Ali , Oday D. Jerew