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Computed tomography (CT) has played a vital role in medical diagnosis, assessment, and therapy planning, etc. In clinical practice, concerns about the increase of X-ray radiation exposure attract more and more attention. To lower the X-ray…

Computed Tomography (CT) reconstruction is a fundamental component to a wide variety of applications ranging from security, to healthcare. The classical techniques require measuring projections, called sinograms, from a full 180$^\circ$…

Low-dose computed tomography (LDCT) aims to minimize the radiation exposure to patients while maintaining diagnostic image quality. However, traditional CT reconstruction algorithms often struggle with the ill-posed nature of the problem,…

Deep learning based solutions are being succesfully implemented for a wide variety of applications. Most notably, clinical use-cases have gained an increased interest and have been the main driver behind some of the cutting-edge data-driven…

Due to the scarcity of annotated data in the medical domain, few-shot learning may be useful for medical image analysis tasks. We design a few-shot learning method using an ensemble of random subspaces for the diagnosis of chest x-rays…

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

In the current paper we consider the Helical Cone Beam CT. This scanning method exposes the patient to large quantities of radiation and results in very large amounts of data being collected and stored. Both these facts are prime motivators…

Conebeam CT using a circular trajectory is quite often used for various applications due to its relative simple geometry. For conebeam geometry, Feldkamp, Davis and Kress algorithm is regarded as the standard reconstruction method, but this…

To study radiotherapy-related adverse effects, detailed dose information (3D distribution) is needed for accurate dose-effect modeling. For childhood cancer survivors who underwent radiotherapy in the pre-CT era, only 2D radiographs were…

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Purpose: This work aims to develop an image reconstruction algorithm for wide-angle digital breast tomosynthesis (DBT) that has improved depth resolution and in-plane contrast while reducing non-uniformity artifacts. Approach: The image…

For conventional computed tomography (CT) image reconstruction tasks, the most popular method is the so-called filtered-back-projection (FBP) algorithm. In it, the acquired Radon projections are usually filtered first by a ramp kernel…

The success of embolisation, a minimally invasive treatment of liver cancer, could be evaluated in the operational room with cone-beam CT by acquiring a dynamic perfusion scan. The reconstruction algorithm must address the issues of low…

Computed tomography has propelled scientific advances in fields from biology to materials science. This technology allows for the elucidation of 3-dimensional internal structure by the attenuation of x-rays through an object at different…

PURPOSE: We develop a practical, iterative algorithm for image-reconstruction in under-sampled tomographic systems, such as digital breast tomosynthesis (DBT). METHOD: The algorithm controls image regularity by minimizing the image total…

Multi-scale 3D characterization is widely used by materials scientists to further their understanding of the relationships between microscopic structure and macroscopic function. Scientific computed tomography (CT) instruments are one of…

Obtaining accurate and reliable images from low-dose computed tomography (CT) is challenging. Regression convolutional neural network (CNN) models that are learned from training data are increasingly gaining attention in low-dose CT…

Objective: This work examines the claim made in the literature that the inverse problem associated with image reconstruction in sparse-view computed tomography (CT) can be solved with a convolutional neural network (CNN). Methods: Training…

Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally complex because of the repeated use of the forward and backward projection. Inspired by this success of deep learning in computer vision…

Ultrafast ultrasound (US) revolutionized biomedical imaging with its capability of acquiring full-view frames at over 1 kHz, unlocking breakthrough modalities such as shear-wave elastography and functional US neuroimaging. Yet, it suffers…