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Related papers: Deterministic Epidemic Models For Ebola Infection …

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A modified, deterministic SEIR model is developed for the 2014 Ebola epidemic occurring in the West African nations of Guinea, Liberia, and Sierra Leone. The model describes the dynamical interaction of susceptible and infected populations,…

Populations and Evolution · Quantitative Biology 2016-11-22 Paul Diaz , Paul Constantine , Kelsey Kalmbach , Eric Jones , Stephen Pankavich

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

Optimization and Control · Mathematics 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

An analytical expression for the optimal control of an Ebola problem is obtained. The analytical solution is found as a first-order approximation to the Pontryagin Maximum Principle via the Euler-Lagrange equation. An implementation of the…

Optimization and Control · Mathematics 2016-12-06 Doracelly Hincapie-Palacio , Juan Ospina , Delfim F. M. Torres

A differential equations model is developed for the 2014 Ebola epidemics in Sierra Leone, Liberia, and Guinea. The model describes the dynamic interactions of the susceptible and infected populations of these countries. The model…

Populations and Evolution · Quantitative Biology 2014-10-23 Cameron Browne , Xi Huo , Pierre Magal , Moussa Seydi , Ousmanne Seydi , Glenn Webb

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

We study a resource allocation problem for containing an infectious disease in a metapopulation subject to resource uncertainty. We propose a two-stage model where the policy maker seeks to allocate resources in both stages where the second…

Optimization and Control · Mathematics 2020-06-03 Ceyda Yaba Best , Amin Khademi , Burak Eksioglu

We propose and study a compartmental model for epidemiology with human behavioral effects. Specifically, our model incorporates governmental prevention measures aimed at lowering the disease infection rate, but we split the population into…

Systems and Control · Electrical Eng. & Systems 2026-02-16 Chloe Ngo , Christian Parkinson , Weinan Wang

Stochastic models are widely used to investigate the spread of epidemics in a complex environment. This paper extends a deterministic SAIRS epidemic model to a stochastic case with limited patient capacity and exposure. We first study the…

Probability · Mathematics 2024-05-20 Xiaohui Zhang , Zhiming Li , Shenglong Chen , Jikai Yang

Much effort has been directed towards using mathematical models to understand and predict contagious disease, in particular Ebola outbreaks. Classical SIR (susceptible-infected-recovered) compartmental models capture well the dynamics of…

Populations and Evolution · Quantitative Biology 2015-12-22 Anca Radulescu , Joanna Herron

Ebola virus disease is a severe hemorrhagic fever with rapid transmission through infected fluids and surfaces. We develop a fractional-order model using Caputo derivatives to capture memory effects in disease dynamics. An eight-compartment…

Optimization and Control · Mathematics 2025-12-22 Noor Muhammad , Md. Nur Alam , Zhang Shiqing

The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…

Optimization and Control · Mathematics 2014-01-30 Helena Sofia Rodrigues

This study develops and analyzes an extended Susceptible, Infected, Hospitalized and Recovered (SIHR) model incorporating time dependent control functions to capture preventive measures (e.g., distancing, mask use) and resource limited…

Populations and Evolution · Quantitative Biology 2025-10-01 Liban Ismail , Yahyeh Souleiman , Saraless Nadarajah , Abdisalam Hassan

This work will study an optimal control problem describing the two-strain SEIR epidemic model. The studied model is in the form of six nonlinear differential equations illustrating the dynamics of the susceptibles and the exposed, the…

Populations and Evolution · Quantitative Biology 2024-04-29 Karam Allali , Mouhamadou A. M. T. Balde , Babacar M. Ndiaye

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

Modelling epidemics via classical population-based models suffers from shortcomings that so-called individual-based models are able to overcome, as they are able to take heterogeneity features into account, such as super-spreaders, and…

Optimization and Control · Mathematics 2022-05-16 C. Courtès , E. Franck , K. Lutz , L. Navoret , Y. Privat

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

In this paper, we consider an adaptive optimal control problem for an SIR/V epidemic model with human behavioral effects.We develop a model where effective management of infectious diseases are monitored by the means of non pharmaceutical…

Physics and Society · Physics 2025-12-09 Nuruzzaman Rahat , Abid Hossain , Muntasir Alam

We consider the problem of the optimal allocation of vaccination and protection measures for the Susceptible-Infected-Recovered-Infected (SIRI) epidemiological model, which generalizes the classical Susceptible-Infected-Recovered (SIR) and…

Optimization and Control · Mathematics 2025-05-09 Urmee Maitra , Ashish R. Hota , Rohit Gupta , Alfred O. Hero

The Ebola epidemic in West Africa is the largest ever recorded, with over 27,000 cases and 11,000 deaths as of June 2015. The public health response was challenged by difficulties with disease surveillance, which impacted subsequent…

Populations and Evolution · Quantitative Biology 2015-08-07 Marisa C. Eisenberg , Joseph N. S. Eisenberg , Jeremy P. D'Silva , Eden V. Wells , Sarah Cherng , Yu-Han Kao , Rafael Meza