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Here, we introduce a novel framework for modelling the spatiotemporal dynamics of disease spread known as conditional logistic individual-level models (CL-ILM's). This framework alleviates much of the computational burden associated with…

Computation · Statistics 2024-09-05 Tahmina Akter , Rob Deardon

Modelling epidemics is crucial for understanding the emergence, transmission, impact and control of diseases. Spatial individual-level models (ILMs) that account for population heterogeneity are a useful tool, accounting for factors such as…

Computation · Statistics 2024-05-03 Chinmoy Roy Rahul , Rob Deardon

Deterministic models are developed for the spatial spread of epidemic diseases in geographical settings. The models are focused on outbreaks that arise from a small number of infected hosts imported into sub-regions of the geographical…

Populations and Evolution · Quantitative Biology 2018-01-08 Pierre Magal , Glenn F. Webb , Yixiang Wu

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

We study an individual-based stochastic spatial epidemic model where the number of locations and the number of individuals at each location both grow to infinity. Each individual is associated with a random infection-age dependent…

Probability · Mathematics 2025-10-21 Guodong Pang , Etienne Pardoux

Partial differential equation (PDE) models for infectious disease have received renewed interest in recent years. Most models of this type extend classical compartmental formulations with additional terms accounting for spatial dynamics,…

Populations and Evolution · Quantitative Biology 2025-04-29 Pierluigi Colli , Gabriela Marinoschi , Elisabetta Rocca , Alex Viguerie

This paper describes the R package EpiILMCT, which allows users to study the spread of infectious disease using continuous time individual level models (ILMs). The package provides tools for simulation from continuous time ILMs that are…

Applications · Statistics 2021-08-17 Waleed Almutiry , Vineetha Warriyar K , Rob Deardon

During epidemics, people will often modify their behaviour patterns over time in response to changes in their perceived risk of spreading or contracting the disease. This can substantially impact the trajectory of the epidemic. However,…

Methodology · Statistics 2023-08-03 Madeline A. Ward , Rob Deardon , Lorna E. Deeth

We study a model for the spread of an infectious disease which incorporates spatial and temporal effects. The model is a delayed multi-type branching process in which types represent geographic regions while infected individuals reproduce…

Probability · Mathematics 2023-01-27 Andrew Hart , Servet Martínez

Individual-level epidemic models are increasingly being used to help understand the transmission dynamics of various infectious diseases. However, fitting such models to individual-level epidemic data is challenging, as we often only know…

Applications · Statistics 2026-02-17 Dirk Douwes-Schultz , Rob Deardon , Alexandra M. Schmidt

Much traditional statistical modelling assumes that the outcome variables of interest are independent of each other when conditioned on the explanatory variables. This assumption is strongly violated in the case of infectious diseases,…

Populations and Evolution · Quantitative Biology 2019-11-28 Timothy Kinyanjui , Thomas House

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

In this article, we introduce the R package EpiILM, which provides tools for simulation from, and inference for, discrete-time individual-level models of infectious disease transmission proposed by Deardon et al. (2010). The inference is…

Applications · Statistics 2020-04-02 Vineetha Warriyar K. V. , Waleed Almutiry , Rob Deardon

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Interaction patterns among individuals play vital roles in spreading infectious diseases. Understanding these patterns and integrating their impact in modeling diffusion dynamics of infectious diseases are important for epidemiological…

Social and Information Networks · Computer Science 2018-04-02 Md Shahzamal , Raja Jurdak , Bernard Mans , Ahmad El Shoghri , Frank De Hoog

A compartment epidemic model for infectious disease spreading is investigated, where movement of individuals is governed by spatial diffusion. The model includes infection age of the infected individuals and assumes a logistic growth of the…

Analysis of PDEs · Mathematics 2023-06-28 Christoph Walker

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

Populations and Evolution · Quantitative Biology 2015-06-11 Joel C. Miller

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

Reliable estimation of spatio-temporal trends in population-level HIV incidence is becoming an increasingly critical component of HIV prevention policy-making. However, direct measurement is nearly impossible. Current, widely used models…

Applications · Statistics 2019-12-04 Timothy M Wolock , Seth R Flaxman , Jeffrey W Eaton
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