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The global public health landscape is perpetually challenged by the looming threat of infectious diseases. Central to addressing this concern is the imperative to prevent and manage disease transmission during pandemics, particularly in…

Populations and Evolution · Quantitative Biology 2024-04-19 Xue Liu , Yue Deng , Jingying Huang , Yuhong Zhang , Jinzhi Lei

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

Many real networks are embedded in a metric space: the interactions among individuals depend on their spatial distances and usually take place among their nearest neighbors. In this paper, we introduce a modified…

Physics and Society · Physics 2015-06-26 Xin-Jian Xu , Wen-Xu Wang , Tao Zhou , Guanrong Chen

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

Numerical Analysis · Mathematics 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Populations and Evolution · Quantitative Biology 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes

We develop Graph-Coupled Hidden Markov Models (GCHMMs) for modeling the spread of infectious disease locally within a social network. Unlike most previous research in epidemiology, which typically models the spread of infection at the level…

Social and Information Networks · Computer Science 2012-10-19 Wen Dong , Alex Pentland , Katherine A. Heller

We simulate a spatial behavioral model of the diffusion of an infection to understand the role of geographic characteristics: the number and distribution of outbreaks, population size, density, and agents' movements. We show that several…

General Economics · Economics 2022-01-31 Alberto Bisin , Andrea Moro

Statistical models used to estimate the spatio-temporal pattern in disease risk from areal unit data represent the risk surface for each time period with known covariates and a set of spatially smooth random effects. The latter act as a…

Applications · Statistics 2016-04-19 Alastair Rushworth , Duncan Lee , Christophe Sarran

The study of infectious disease epidemiology for multi-type disease pathogens requires modelling techniques that account for the complex interactions existing between strains across geography and time. In this paper, we propose a novel…

Methodology · Statistics 2026-05-06 Matthew Adeoye , Simon E. F. Spencer , Xavier Didelot

Partial differential equation (PDE) models for infectious diseases, while less common than their ordinary differential equation (ODE) counterparts, have found successful applications for many years. Such models are typically of…

Populations and Evolution · Quantitative Biology 2026-01-27 Alex Viguerie , Malú Grave , Alvaro L. G. A. Coutinho , Alessandro Veneziani , Thomas J. R. Hughes

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

Among the realistic ingredients to be considered in the computational modeling of infectious diseases, human mobility represents a crucial challenge both on the theoretical side and in view of the limited availability of empirical data. In…

Physics and Society · Physics 2010-02-04 Duygu Balcan , Vittoria Colizza , Bruno Goncalves , Hao Hu , Jose J. Ramasco , Alessandro Vespignani

We develop a spatially dependent generalisation to the Wells-Riley model and its extensions applied to COVID-19, that determines the infection risk due to airborne transmission of viruses. We assume that the concentration of infectious…

Quantitative Methods · Quantitative Biology 2021-05-19 Zechariah Lau , Ian M. Griffiths , Aaron English , Katerina Kaouri

Spatial individual-level models (ILMs) provide a flexible framework for modelling infectious disease transmission across populations with known locations. Bayesian inference for these models relies on Markov chain Monte Carlo (MCMC), which…

Computation · Statistics 2026-05-29 Yicheng Mao , Rob Deardon

Many important questions in infectious disease epidemiology involve the effects of covariates (e.g., age or vaccination status) on infectiousness and susceptibility, which can be measured in studies of transmission in households or other…

Applications · Statistics 2025-06-27 Yushuf Sharker , Zaynab Diallo , Wasiur R. KhudaBukhsh , Eben Kenah

With the exponential growth in the world population and the constant increase in human mobility, the danger of outbreaks of epidemics is rising. Especially in high density urban areas such as public transport and transfer points, where…

Other Computer Science · Computer Science 2012-01-04 Mei Shan , Zhou Xuan , Zhu Yifan , Zu Zhenghu , Zheng Tao , A. V. Boukhanovsky , P. M. A Sloot

The viral load is known to be a chief predictor of the risk of transmission of infectious diseases. In this work, we investigate the role of the individuals' viral load in the disease transmission by proposing a new…

Adaptation and Self-Organizing Systems · Physics 2023-03-29 Rossella Della Marca , Nadia Loy , Andrea Tosin

This study investigates the spatial integration of agent-based models (ABMs) and compartmental models for infectious disease modeling, presenting a novel hybrid approach and examining its implications. ABMs offer detailed insights by…

Populations and Evolution · Quantitative Biology 2025-02-06 Inan Bostanci , Tim Conrad

We extend the classical SIR model of infectious disease spread to account for time dependence in the parameters, which also include diffusivities. The temporal dependence accounts for the changing characteristics of testing, quarantine and…

Populations and Evolution · Quantitative Biology 2020-07-03 Zhenlin Wang , Xiaoxuan Zhang , Gregory Teichert , Mariana Carrasco-Teja , Krishna Garikipati

Infectious diseases remain one of the major causes of human mortality and suffering. Mathematical models have been established as an important tool for capturing the features that drive the spread of the disease, predicting the progression…