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Modeling biological sequences such as DNA, RNA, and proteins is crucial for understanding complex processes like gene regulation and protein synthesis. However, most current models either focus on a single type or treat multiple types of…

Genomics · Quantitative Biology 2024-10-16 Weixi Xiang , Xueting Han , Xiujuan Chai , Jing Bai

Neural networks are increasingly used in real-time systems, such as automated driving applications. This requires high-performance hardware with predictable timing behavior. State-of-the-art real-time hardware is limited in memory and…

Hardware Architecture · Computer Science 2024-10-15 Maximilian Kirschner , Konstantin Dudzik , Jürgen Becker

This study introduces bifurcated attention, a method designed to enhance language model inference in shared-context batch decoding scenarios. Our approach addresses the challenge of redundant memory IO costs, a critical factor contributing…

Processing-in-memory (PIM) has emerged as an enabler for the energy-efficient and high-performance acceleration of deep learning (DL) workloads. Resistive random-access memory (ReRAM) is one of the most promising technologies to implement…

Hardware Architecture · Computer Science 2024-03-29 Harsh Sharma , Gaurav Narang , Janardhan Rao Doppa , Umit Ogras , Partha Pratim Pande

The research interest in specialized hardware accelerators for deep neural networks (DNN) spikes recently owing to their superior performance and efficiency. However, today's DNN accelerators primarily focus on accelerating specific…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-11 Cong Guo , Yangjie Zhou , Jingwen Leng , Yuhao Zhu , Zidong Du , Quan Chen , Chao Li , Bin Yao , Minyi Guo

For the last thirty years, several Dynamic Memory Managers (DMMs) have been proposed. Such DMMs include first fit, best fit, segregated fit and buddy systems. Since the performance, memory usage and energy consumption of each DMM differs,…

Neural and Evolutionary Computing · Computer Science 2024-07-16 José L. Risco-Martín , David Atienza , J. Manuel Colmenar , Oscar Garnica

Edge computing aims to enable edge devices, such as IoT devices, to process data locally instead of relying on the cloud. However, deep learning techniques like computer vision and natural language processing can be computationally…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Oshin Dutta , Tanu Kanvar , Sumeet Agarwal

Transformers have revolutionized AI in natural language processing and computer vision, but their large computation and memory demands pose major challenges for hardware acceleration. In practice, end-to-end throughput is often limited by…

Hardware Architecture · Computer Science 2026-03-20 Qunyou Liu , Marina Zapater , David Atienza

Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional…

Genomics · Quantitative Biology 2020-02-11 Andreas Georgiou , Vincent Fortuin , Harun Mustafa , Gunnar Rätsch

Distributed approaches based on the map-reduce programming paradigm have started to be proposed in the bioinformatics domain, due to the large amount of data produced by the next-generation sequencing techniques. However, the use of…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-05 Umberto Ferraro Petrillo , Mara Sorella , Giuseppe Cattaneo , Raffaele Giancarlo , Simona Rombo

Retrieval-Augmented Generation (RAG) has shown significant improvements in various natural language processing tasks by integrating the strengths of large language models (LLMs) and external knowledge databases. However, RAG introduces long…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-26 Chao Jin , Zili Zhang , Xuanlin Jiang , Fangyue Liu , Xin Liu , Xuanzhe Liu , Xin Jin

Real-time systems, particularly those used in domains like automated driving, are increasingly adopting neural networks. From this trend arises the need for high-performance hardware exhibiting predictable timing behavior. While…

Hardware Architecture · Computer Science 2026-02-26 Maximilian Kirschner , Konstantin Dudzik , Ben Krusekamp , Jürgen Becker

Multi-core architectures feature an intricate hierarchy of cache memories, with multiple levels and sizes. To adequately decompose an application according to the traits of a particular memory hierarchy is a cumbersome task that may be…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-20 Hervé Paulino , Nuno Delgado

Ultra low-bit quantization brings substantial efficiency for Transformer-based models, but the accuracy degradation and limited GPU support hinder its wide usage. In this paper, we analyze zero-point distortion in binarization and propose a…

Machine Learning · Computer Science 2026-04-07 Yifu Ding , Xianglong Liu , Shenghao Jin , Jinyang Guo , Jiwen Lu

Processing-in-memory (PIM) architectures bring computation closer to data, reducing the processor-memory transfer bottleneck in traditional processor-centric designs. Novel hardware solutions, such as UPMEM's in-memory processing…

Emerging Technologies · Computer Science 2026-04-10 Peterson Yuhala , Mpoki Mwaisela , Pascal Felber , Valerio Schiavoni

A new array based data structure named black-white array (BWA) is introduced as an effective and efficient alternative to the list or tree based data structures for dynamic data set. It consists of two sub-arrays, one white and one black of…

Data Structures and Algorithms · Computer Science 2020-04-21 Z. George Mou

The global scarcity of GPUs necessitates more sophisticated strategies for Deep Learning jobs in shared cluster environments. Accurate estimation of how much GPU memory a job will require is fundamental to enabling advanced scheduling and…

Performance · Computer Science 2025-10-27 Jiabo Shi , Dimitrios Pezaros , Yehia Elkhatib

Most commercial embedded devices have been deployed with a single processor architecture. The code size and complexity of applications running on embedded devices are rapidly increasing due to the emergence of application business models…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-01-26 Geunsik Lim , Changwoo Min , YoungIk Eom

Latest algorithms for automatic neural architecture search perform remarkable but are basically directionless in search space and computational expensive in training of every intermediate architecture. In this paper, we propose a method for…

Neural and Evolutionary Computing · Computer Science 2019-08-28 Hui Zhu , Zhulin An , Chuanguang Yang , Kaiqiang Xu , Erhu Zhao , Yongjun Xu

Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run. This…

Quantitative Methods · Quantitative Biology 2016-11-18 Stephanie Dodson , Darrell O. Ricke , Jeremy Kepner