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Performing massive data mining experiments with multiple datasets and methods is a common task faced by most bioinformatics and computational biology laboratories. WEKA is a machine learning package designed to facilitate this task by…

Mathematical Software · Computer Science 2014-12-19 Madison Flannery , David M Budden , Alexandre Mendes

Deep neural network (DNN) inference using reduced integer precision has been shown to achieve significant improvements in memory utilization and compute throughput with little or no accuracy loss compared to full-precision floating-point.…

Hardware Architecture · Computer Science 2023-04-11 Yuzong Chen , Mohamed S. Abdelfattah

The growing volume of data in modern applications has led to significant computational costs in conventional processor-centric systems. Processing-in-memory (PIM) architectures alleviate these costs by moving computation closer to memory,…

Hardware Architecture · Computer Science 2025-04-23 Geraldo F. Oliveira , Alain Kohli , David Novo , Ataberk Olgun , A. Giray Yaglikci , Saugata Ghose , Juan Gómez-Luna , Onur Mutlu

Genome analysis fundamentally starts with a process known as read mapping, where sequenced fragments of an organism's genome are compared against a reference genome. Read mapping is currently a major bottleneck in the entire genome analysis…

Hardware Architecture · Computer Science 2020-10-29 Mohammed Alser , Zülal Bingöl , Damla Senol Cali , Jeremie Kim , Saugata Ghose , Can Alkan , Onur Mutlu

We introduce Larq Compute Engine, the world's fastest Binarized Neural Network (BNN) inference engine, and use this framework to investigate several important questions about the efficiency of BNNs and to design a new state-of-the-art BNN…

Machine Learning · Computer Science 2021-02-23 Tom Bannink , Arash Bakhtiari , Adam Hillier , Lukas Geiger , Tim de Bruin , Leon Overweel , Jelmer Neeven , Koen Helwegen

The Transformer architecture, underpinned by the self-attention mechanism, has become the de facto standard for sequence modeling tasks. However, its core computational primitive scales quadratically with sequence length (O(N^2)), creating…

Computation and Language · Computer Science 2025-09-03 Rishiraj Acharya

Genome sequence analysis is a powerful tool in medical and scientific research. Considering the inevitable sequencing errors and genetic variations, approximate string matching (ASM) has been adopted in practice for genome sequencing.…

With the fast development of Internet of things (IoT), the fifth generation (5G) wireless networks need to provide massive connectivity of IoT devices and meet the demand for low latency. To satisfy these requirements, Non-Orthogonal…

Networking and Internet Architecture · Computer Science 2018-02-07 Abbas Kiani , Nirwan Ansari

Data movement in memory-intensive workloads, such as deep learning, incurs energy costs that are over three orders of magnitude higher than the cost of computation. Since these workloads involve frequent data transfers between memory and…

Hardware Architecture · Computer Science 2025-02-05 Bahareh Khabbazan , Marc Riera , Antonio González

The field of neuromorphic computing has gained significant attention in recent years, aiming to bridge the gap between the efficiency of biological neural networks and the performance of artificial intelligence systems. This paper…

Neural and Evolutionary Computing · Computer Science 2024-08-23 Jiahao Qin , Feng Liu

Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is…

Quantitative Methods · Quantitative Biology 2015-05-27 Kévin Vervier , Pierre Mahé , Maud Tournoud , Jean-Baptiste Veyrieras , Jean-Philippe Vert

We present a simple dynamic batching approach applicable to a large class of dynamic architectures that consistently yields speedups of over 10x. We provide performance bounds when the architecture is not known a priori and a stronger bound…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Joseph Suarez , Clare Zhu

Ever since the Dennard scaling broke down in the early 2000s and the frequency of the CPUs stalled, vendors have started to increase the core count in each CPU chip at the expense of introducing heterogeneity, thus ushering the era of NUMA…

Databases · Computer Science 2026-01-22 Yeasir Rayhan , Walid G. Aref

Accelerating deep model training and inference is crucial in practice. Existing deep learning frameworks usually concentrate on optimizing training speed and pay fewer attentions to inference-specific optimizations. Actually, model…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-12 Yongchao Liu , Yue Jin , Yong Chen , Teng Teng , Hang Ou , Rui Zhao , Yao Zhang

This paper introduces a groundbreaking digital neuromorphic architecture that innovatively integrates Brain Code Unit (BCU) and Fundamental Code Unit (FCU) using mixedsignal design methodologies. Leveraging open-source datasets and the…

Hardware Architecture · Computer Science 2024-03-19 Murat Isik , Sols Miziev , Wiktoria Pawlak , Newton Howard

For the 6G mobile networks, in-situ model downloading has emerged as an important use case to enable real-time adaptive artificial intelligence on edge devices. However, the simultaneous downloading of diverse and high-dimensional models to…

Information Theory · Computer Science 2023-07-31 Hai Wu , Qunsong Zeng , Kaibin Huang

Computing is bottlenecked by data. Large amounts of application data overwhelm storage capability, communication capability, and computation capability of the modern machines we design today. As a result, many key applications' performance,…

Hardware Architecture · Computer Science 2020-08-17 Onur Mutlu

The rapid scaling of large language models (LLMs) has unveiled critical limitations in current hardware architectures, including constraints in memory capacity, computational efficiency, and interconnection bandwidth. DeepSeek-V3, trained…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-24 Chenggang Zhao , Chengqi Deng , Chong Ruan , Damai Dai , Huazuo Gao , Jiashi Li , Liyue Zhang , Panpan Huang , Shangyan Zhou , Shirong Ma , Wenfeng Liang , Ying He , Yuqing Wang , Yuxuan Liu , Y. X. Wei

Convolutional Neural Networks (CNNs) serve various applications with diverse performance and resource requirements. Model-aware CNN accelerators best address these diverse requirements. These accelerators usually combine multiple dedicated…

Hardware Architecture · Computer Science 2025-04-08 Fareed Qararyah , Mohammad Ali Maleki , Pedro Trancoso

Task offloading and scheduling in Mobile Edge Computing (MEC) are vital for meeting the low-latency demands of modern IoT and dynamic task scheduling scenarios. MEC reduces the processing burden on resource-constrained devices by enabling…

Networking and Internet Architecture · Computer Science 2026-01-23 Arild Yonkeu , Mohammadreza Amini , Burak Kantarci
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