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With the advance in genome sequencing technology, the lengths of deoxyribonucleic acid (DNA) sequencing results are rapidly increasing at lower prices than ever. However, the longer lengths come at the cost of a heavy computational burden…

This paper introduces SENMap, a mapping and synthesis tool for scalable, energy-efficient neuromorphic computing architecture frameworks. SENECA is a flexible architectural design optimized for executing edge AI SNN/ANN inference…

Improving single-thread performance remains a critical challenge in modern processor design, as conventional approaches such as deeper speculation, wider pipelines, and complex out-of-order execution face diminishing returns. This work…

We present exa-AMD, an open-source, high-performance framework designed for accelerated materials discovery on modern supercomputers. exa-AMD overcomes key computational bottlenecks in large-scale structure prediction through task-based…

In this work we present the Secure Machine, SeM for short, a CPU architecture extension for secure computing. SeM uses a small amount of in-chip additional hardware that monitors key communication channels inside the CPU chip, and only acts…

This paper presents EasyRAG, a simple, lightweight, and efficient retrieval-augmented generation framework for automated network operations. Our framework has three advantages. The first is accurate question answering. We designed a…

High-performance, multi-core processors are the key to accelerating workloads in several application domains. To continue to scale performance at the limit of Moore's Law and Dennard scaling, software and hardware designers have turned to…

As machine learning gets deployed more and more widely, and model sizes continue to grow, improving computational efficiency during model inference has become a key challenge. In many commonly used model architectures, including…

With the booming of next generation sequencing technology and its implementation in clinical practice and life science research, the need for faster and more efficient data analysis methods becomes pressing in the field of sequencing. Here…

Parallel applications are extremely challenging to achieve the optimal performance on the NUMA architecture, which necessitates the assistance of profiling tools. However, existing NUMA-profiling tools share some similar shortcomings, such…

Page placement is a critical problem for memoryintensive applications running on a shared-memory multiprocessor with a non-uniform memory access (NUMA) architecture. State-of-the-art page placement mechanisms interleave pages evenly across…

Background: Short-read aligners have recently gained a lot of speed by exploiting the massive parallelism of GPU. An uprising alternative to GPU is Intel MIC; supercomputers like Tianhe-2, currently top of TOP500, is built with 48,000 MIC…

The rapid advancement of embedded multicore and many-core systems has revolutionized computing, enabling the development of high-performance, energy-efficient solutions for a wide range of applications. As models scale up in size, data…

FPGAs are a promising platform for accelerating Deep Learning (DL) applications, due to their high performance, low power consumption, and reconfigurability. Recently, the leading FPGA vendors have enhanced their architectures to more…

Designing energy-efficient networks is of critical importance for enabling state-of-the-art deep learning in mobile and edge settings where the computation and energy budgets are highly limited. Recently, Liu et al. (2019) framed the search…

Deep neural networks have achieved impressive results in computer vision and machine learning. Unfortunately, state-of-the-art networks are extremely compute and memory intensive which makes them unsuitable for mW-devices such as IoT…

Graph neural networks (GNNs) have gained significant interest for applications such as citation network analysis and drug discovery due to their ability to apply machine learning techniques on graph-structured data. GNNs typically employ a…

Homomorphic encryption (HE) allows direct computations on encrypted data. Despite numerous research efforts, the practicality of HE schemes remains to be demonstrated. In this regard, the enormous size of ciphertexts involved in HE…

The growing demand for efficient, high-performance processing in machine learning (ML) and image processing has made hardware accelerators, such as GPUs and Data Streaming Accelerators (DSAs), increasingly essential. These accelerators…

Real-time semantic segmentation presents the dual challenge of designing efficient architectures that capture large receptive fields for semantic understanding while also refining detailed contours. Vision transformers model long-range…