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In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases…

Quantitative Methods · Quantitative Biology 2022-10-18 August George , Doo Nam Kim , Trevor Moser , Ian T. Gildea , James E. Evans , Margaret S. Cheung

In this paper we develop a novel Topological Data Analysis (TDA) approach for studying graph representations of time series of dynamical systems. Specifically, we show how persistent homology, a tool from TDA, can be used to yield a…

Chaotic Dynamics · Physics 2020-01-28 Audun Myers , Elizabeth Munch , Firas A. Khasawneh

The topology of many real complex networks has been conjectured to be embedded in hidden metric spaces, where distances between nodes encode their likelihood of being connected. Besides of providing a natural geometrical interpretation of…

Physics and Society · Physics 2017-01-23 Antoine Allard , M. Ángeles Serrano , Guillermo García-Pérez , Marián Boguñá

Topological Data Analysis (TDA) offers a suite of computational tools that provide quantified shape features in high dimensional data that can be used by modern statistical and predictive machine learning (ML) models. In particular,…

Cryptography and Security · Computer Science 2023-07-06 Dominic Gold , Koray Karabina , Francis C. Motta

A fundamental tool in topological data analysis is persistent homology, which allows extraction of information from complex datasets in a robust way. Persistent homology assigns a module over a principal ideal domain to a one-parameter…

Algebraic Topology · Mathematics 2019-06-19 Heather A. Harrington , Nina Otter , Hal Schenck , Ulrike Tillmann

In real-world systems, the relationships and connections between components are highly complex. Real systems are often described as networks, where nodes represent objects in the system and edges represent relationships or connections…

Algebraic Topology · Mathematics 2024-06-24 Shen Zhang

Time dependence is a universal phenomenon in nature, and a variety of mathematical models in terms of dynamical systems have been developed to understand the time-dependent behavior of real-world problems. Originally constructed to analyze…

Algebraic Topology · Mathematics 2018-02-14 Zixuan Cang , Elizabeth Munch , Guo-Wei Wei

Percolation theory has been largely used in the study of structural properties of complex networks such as the robustness, with remarkable results. Nevertheless, a purely topological description is not sufficient for a correct…

Statistical Mechanics · Physics 2016-08-31 Luca Dall'Asta

We develop an analysis pipeline for characterizing the topology of large scale structure and extracting cosmological constraints based on persistent homology. Persistent homology is a technique from topological data analysis that quantifies…

Cosmology and Nongalactic Astrophysics · Physics 2021-06-14 Matteo Biagetti , Alex Cole , Gary Shiu

Convective mixing in porous media is crucial in both geophysical and industrial fields, spanning applications ranging from carbon dioxide sequestration to contaminant transport in groundwater. Key processes are affected by convective heat…

Fluid Dynamics · Physics 2025-12-29 Marco De Paoli , Sergio Pirozzoli , Lou Kondic

Topological data analysis (TDA) is a rising branch in modern applied mathematics. It extracts topological structures as features of a given space and uses these features to analyze digital data. Persistent homology, one of the central tools…

Algebraic Topology · Mathematics 2025-05-26 Chuan-Shen Hu

Persistent homology (PH) has been widely applied to graph data to extract topological features. However, little attention has been paid to how different distance functions on a graph affect the resulting persistence barcodes and their…

Algebraic Topology · Mathematics 2026-02-17 Eunwoo Heo , Byeongchan Choi , Jae-Hun Jung

Machine learning has emerged as a powerful approach in materials discovery. Its major challenge is selecting features that create interpretable representations of materials, useful across multiple prediction tasks. We introduce an…

Through the use of examples, we explain one way in which applied topology has evolved since the birth of persistent homology in the early 2000s. The first applications of topology to data emphasized the global shape of a dataset, such as…

Algebraic Topology · Mathematics 2021-04-23 Henry Adams , Michael Moy

Hyperuniform many-particle distributions possess a local number variance that grows more slowly than the volume of an observation window, implying that the local density is effectively homogeneous beyond a few characteristic length scales.…

Statistical Mechanics · Physics 2015-05-27 Chase E. Zachary , Yang Jiao , Salvatore Torquato

It has been observed that the topology of the native state is an important determinant of protein folding kinetics and there is a significant correlation between folding rate and relative contact order (RCO) in two-state small single-domain…

Biological Physics · Physics 2009-07-23 Taisong Zou , Canan Atilgan , Ali Rana Atilgan , S. Banu Ozkan

Persistent Homology is a powerful tool in Topological Data Analysis (TDA) to capture topological properties of data succinctly at different spatial resolutions. For graphical data, shape, and structure of the neighborhood of individual data…

Social and Information Networks · Computer Science 2018-11-12 Sumit Bhatia , Bapi Chatterjee , Deepak Nathani , Manohar Kaul

Techniques from computational topology, in particular persistent homology, are becoming increasingly relevant for data analysis. Their stable metrics permit the use of many distance-based data analysis methods, such as multidimensional…

Algebraic Topology · Mathematics 2021-01-20 Bastian Rieck , Filip Sadlo , Heike Leitte

Structural and thermodynamic properties of ionic fluids are related to those of a simpler ``mimic'' system with short ranged intermolecular interactions in a spatially varying effective field by use of Local Molecular Field (LMF) theory,…

Statistical Mechanics · Physics 2007-05-23 Yng-gwei Chen , Charanbir Kaur , John D. Weeks

In this work we use the persistent homology method, a technique in topological data analysis (TDA), to extract essential topological features from the data space and combine them with deep learning features for classification tasks. In TDA,…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Mariana Dória Prata Lima , Gilson Antonio Giraldi , Gastão Florêncio Miranda Junior