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Topological data analysis (TDA) is an active field of mathematics for quantifying shape in complex data. Standard methods in TDA such as persistent homology (PH) are typically focused on the analysis of data consisting of a single entity…

The ability to reroute and control flow is vital to the function of venation networks across a wide range of organisms. By modifying individual edges in these networks, either by adjusting edge conductances or creating and destroying edges,…

Soft Condensed Matter · Physics 2021-01-14 Jason W. Rocks , Andrea J. Liu , Eleni Katifori

We present a machine learning approach that leverages persistent homology to classify bacterial flagellar motors into two functional states: rotated and stalled. By embedding protein structural data into a topological framework, we extract…

Biomolecules · Quantitative Biology 2025-12-19 Zakaria Lamine , Abdelatif Hafid , Mohamed Rahouti

Persistent homology (PH) is a method used in topological data analysis (TDA) to study qualitative features of data that persist across multiple scales. It is robust to perturbations of input data, independent of dimensions and coordinates,…

Algebraic Topology · Mathematics 2017-09-13 Nina Otter , Mason A. Porter , Ulrike Tillmann , Peter Grindrod , Heather A. Harrington

Topological properties of native folds are obtained from statistical analysis of 160 low homology proteins covering the four structural classes. This is done analysing one, two and three-vertex joint distribution of quantities related to…

Biological Physics · Physics 2007-05-23 Nelson Augusto Alves , Alexandre Souto Martinez

A central problem in data-driven scientific inquiry is how to interpret structure in noisy, high-dimensional data. Topological data analysis (TDA) provides a solution via persistent homology, which encodes features of interest as…

Algebraic Topology · Mathematics 2026-02-04 Christian Lentz , Gregory Henselman-Petrusek , Lori Ziegelmeier

The intermolecular interactions in the title compound are investigated using self-consistent charge density functional based tight binding molecular dynamics. Emphasis is put on the analysis of correlated motions of ion pairs using ideas of…

Chemical Physics · Physics 2016-03-22 Tobias Zentel , Oliver Kühn

Persistent homology (PH) is a crucial concept in computational topology, providing a multiscale topological description of a space. It is particularly significant in topological data analysis, which aims to make statistical inference from a…

Machine Learning · Statistics 2025-11-25 Sing-Yuan Yeh , Chun-Hao Yang

Hyperuniformity, the suppression of density fluctuations at large length scales, is observed across a wide variety of domains, from cosmology to condensed matter and biological systems. Although the standard definition of hyperuniformity…

Statistical Mechanics · Physics 2024-05-07 Marco Salvalaglio , Dominic J. Skinner , Jörn Dunkel , Axel Voigt

An Important tool in the field topological data analysis is known as persistent Homology (PH) which is used to encode abstract representation of the homology of data at different resolutions in the form of persistence diagram (PD). In this…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Aras Asaad , Dashti Ali , Taban Majeed , Rasber Rashid

In this work, we introduce a novel approach based on algebraic topology to enhance graph convolution and attention modules by incorporating local topological properties of the data. To do so, we consider the framework of sheaf neural…

Machine Learning · Computer Science 2023-11-20 Gabriele Cesa , Arash Behboodi

Topological Data Analysis (TDA) provides tools to describe the shape of data, but integrating topological features into deep learning pipelines remains challenging, especially when preserving local geometric structure rather than…

Machine Learning · Computer Science 2026-04-21 Elena Xinyi Wang , Arnur Nigmetov , Dmitriy Morozov

We present mathematical models based on persistent homology for analyzing force distributions in particulate systems. We define three distinct chain complexes: digital, position, and interaction, motivated by different capabilities of…

Soft Condensed Matter · Physics 2014-09-02 M. Kramar , A. Goullet , L. Kondic , K. Mischaikow

A reaction route map (RRM) constructed using the GRRM program is a collection of elementary reaction pathways, each of which comprises two equilibrium (EQ) geometries and one transition state (TS) geometry connected by an intrinsic reaction…

This work introduces a number of algebraic topology approaches, such as multicomponent persistent homology, multi-level persistent homology and electrostatic persistence for the representation, characterization, and description of small…

Quantitative Methods · Quantitative Biology 2018-02-07 Zixuan Cang , Lin Mu , Guowei Wei

This paper is a cursory study on how topological features are preserved within the internal representations of neural network layers. Using techniques from topological data analysis, namely persistent homology, the topological features of a…

Machine Learning · Computer Science 2022-08-16 Archie Shahidullah

Persistent homology (PH) studies the topology of data across multiple scales by building nested collections of topological spaces called filtrations, computing homology and returning an algebraic object that can be vizualised as a…

Algebraic Topology · Mathematics 2024-11-14 David Beers , Heather A Harrington , Jacob Leygonie , Uzu Lim , Louis Theran

Persistent homology tracks topological features across geometric scales, encoding birth and death of cycles as barcodes. We develop a complementary theory where the filtration parameter is algebraic precision rather than geometric scale.…

Algebraic Topology · Mathematics 2025-11-04 Robert Ghrist , Cassie Ding

Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

Capturing the dynamics of active particles, i.e., small self-propelled agents that both deform and are deformed by a fluid in which they move is a formidable problem as it requires coupling fine scale hydrodynamics with large scale…

Soft Condensed Matter · Physics 2025-09-09 Sadra Saremi , Amirhossein Ahmadkhan Kordbacheh