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Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

We explore the hyperparameters and introduce a methodological framework to convert disease patterns from time series data of blood test results into correlation graphs for causal hypothesis exploration. The networks represent hypotheses…

Other Quantitative Biology · Quantitative Biology 2025-12-29 David Patrick Duys Montealegre , Alexander Fulton , Mahta Haghighat Ghahfarokhi , Abicumaran Uthamacumaran , Hector Zenil

Electronic health records contain rich textual data which possess critical predictive information for machine-learning based diagnostic aids. However many traditional machine learning methods fail to simultaneously integrate both vector…

Machine Learning · Computer Science 2012-07-31 Thomas Perry , Hongyuan Zha , Patricio Frias , Dadan Zeng , Mark Braunstein

Diffuse Large B-cell Lymphoma (DLBCL) is a lymphatic cancer involving one or more lymph nodes and extranodal sites. Its diagnostic and follow-up rely on Positron Emission Tomography (PET) and Computed Tomography (CT). After diagnosis, the…

In this work, we investigate unsupervised representation learning on medical time series, which bears the promise of leveraging copious amounts of existing unlabeled data in order to eventually assist clinical decision making. By evaluating…

Machine Learning · Computer Science 2018-12-04 Xinrui Lyu , Matthias Hueser , Stephanie L. Hyland , George Zerveas , Gunnar Raetsch

Early prediction of mortality and length of stay(LOS) of a patient is vital for saving a patient's life and management of hospital resources. Availability of electronic health records(EHR) makes a huge impact on the healthcare domain and…

Machine Learning · Computer Science 2020-12-01 Batuhan Bardak , Mehmet Tan

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

Computation and Language · Computer Science 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

Clinical outcome or severity prediction from medical images has largely focused on learning representations from single-timepoint or snapshot scans. It has been shown that disease progression can be better characterized by temporal imaging.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-01 Aishik Konwer , Xuan Xu , Joseph Bae , Chao Chen , Prateek Prasanna

Computational models that forecast the progression of Alzheimer's disease at the patient level are extremely useful tools for identifying high risk cohorts for early intervention and treatment planning. The state-of-the-art work in this…

Machine Learning · Computer Science 2019-12-30 Surya Teja Devarakonda , Joie Yeahuay Wu , Yi Ren Fung , Madalina Fiterau

We demonstrate a simple strategy to cope with missing data in sequential inputs, addressing the task of multilabel classification of diagnoses given clinical time series. Collected from the pediatric intensive care unit (PICU) at Children's…

Machine Learning · Computer Science 2016-11-14 Zachary C. Lipton , David C. Kale , Randall Wetzel

Many applications collect a large number of time series, for example, the financial data of companies quoted in a stock exchange, the health care data of all patients that visit the emergency room of a hospital, or the temperature sequences…

Information Theory · Computer Science 2017-02-09 Jonathan Mei , José M. F. Moura

In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one…

Machine Learning · Computer Science 2018-12-03 Eli Sherman , Hitinder Gurm , Ulysses Balis , Scott Owens , Jenna Wiens

Electronic health records contain valuable information for monitoring patients' health trajectories over time. Disease progression models have been developed to understand the underlying patterns and dynamics of diseases using these data as…

Healthcare professionals have long envisioned using the enormous processing powers of computers to discover new facts and medical knowledge locked inside electronic health records. These vast medical archives contain time-resolved…

Machine Learning · Computer Science 2020-05-15 Ahmed Allam , Matthias Dittberner , Anna Sintsova , Dominique Brodbeck , Michael Krauthammer

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from…

Machine Learning · Computer Science 2026-04-22 Lei Liu , Jialin Chen , Kathy Macropol

Financial institutions obtain enormous amounts of data about user transactions and money transfers, which can be considered as a large graph dynamically changing in time. In this work, we focus on the task of predicting new interactions in…

Machine Learning · Statistics 2020-01-24 Valentina Shumovskaia , Kirill Fedyanin , Ivan Sukharev , Dmitry Berestnev , Maxim Panov

Predicting the future paths of an agent's neighbors accurately and in a timely manner is central to the autonomous applications for collision avoidance. Conventional approaches, e.g., LSTM-based models, take considerable computational costs…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Chengxin Wang , Shaofeng Cai , Gary Tan

Many areas of research are characterised by the deluge of large-scale highly-dimensional time-series data. However, using the data available for prediction and decision making is hampered by the current lag in our ability to uncover and…

Artificial Intelligence · Computer Science 2020-11-24 Zina Ibrahim , Honghan Wu , Richard Dobson

There is a long history of building predictive models in healthcare using tabular data from electronic medical records. However, these models fail to extract the information found in unstructured clinical notes, which document diagnosis,…

Computation and Language · Computer Science 2025-04-18 David Anderson , Michaela Anderson , Margret Bjarnadottir , Stephen Mahar , Shriyan Reyya