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Working memory requires the brain to maintain information from the recent past to guide ongoing behavior. Neurons can contribute to this capacity by slowly integrating their inputs over time, creating persistent activity that outlasts the…

Neurons and Cognition · Quantitative Biology 2025-11-20 Nicoas Zucchet , Qianqian Feng , Axel Laborieux , Friedemann Zenke , Walter Senn , João Sacramento

Mixture-of-Experts is a promising approach for edge AI with low-batch inference. Yet, on-device deployments often face limited on-chip memory and severe workload imbalance; the prevalent use of offloading further incurs off-chip memory…

Hardware Architecture · Computer Science 2026-03-31 Songchen Ma , Hongyi Li , Weihao Zhang , Yonghao Tan , Pingcheng Dong , Yu Liu , Lan Liu , Yuzhong Jiao , Xuejiao Liu , Luhong Liang , Kwang-Ting Cheng

This paper studies an input-driven one-state differential equation model initially developed for an experimentally demonstrated dynamic molecular switch that switches like synapses in the brain do. The linear-in-the-state and…

Machine Learning · Computer Science 2025-08-22 H. I. Nurdin , C. A. Nijhuis

In the context of neuroscience the elapsed-time model is an age-structured equation that describes the behavior of interconnected spiking neurons through the time since the last discharge, with many interesting dynamics depending on the…

Analysis of PDEs · Mathematics 2025-07-18 María J Cáceres , José A Cañizo , Nicolas Torres

Due to the point-like nature of neuronal spiking, efficient neural network simulators often employ event-based simulation schemes for synapses. Yet many types of synaptic plasticity rely on the membrane potential of the postsynaptic cell as…

Neurons and Cognition · Quantitative Biology 2022-04-05 Jonas Stapmanns , Jan Hahne , Moritz Helias , Matthias Bolten , Markus Diesmann , David Dahmen

Mixed-signal analog/digital circuits emulate spiking neurons and synapses with extremely high energy efficiency, an approach known as "neuromorphic engineering". However, analog circuits are sensitive to process-induced variation among…

Machine Learning · Computer Science 2022-09-13 Julian Büchel , Dmitrii Zendrikov , Sergio Solinas , Giacomo Indiveri , Dylan R. Muir

Various animals, including humans, have been suggested to perform Bayesian inferences to handle noisy, time-varying external information. In performing Bayesian inference, the prior distribution must be shaped by sampling noisy external…

Neurons and Cognition · Quantitative Biology 2022-10-25 Kohei Ichikawa , Kunihiko Kaneko

Much of studies on neural computation are based on network models of static neurons that produce analog output, despite the fact that information processing in the brain is predominantly carried out by dynamic neurons that produce discrete…

Neurons and Cognition · Quantitative Biology 2017-06-21 Dongsung Huh , Terrence J. Sejnowski

We present a SNN simulator which scales to millions of neurons, billions of synapses, and 8 GPUs. This is made possible by 1) a novel, cache-aware spike transmission algorithm 2) a model parallel multi-GPU distribution scheme and 3) a…

Neural and Evolutionary Computing · Computer Science 2021-09-23 Dennis Bautembach , Iason Oikonomidis , Antonis Argyros

Information in neural networks is represented as weighted connections, or synapses, between neurons. This poses a problem as the primary computational bottleneck for neural networks is the vector-matrix multiply when inputs are multiplied…

Fast multipole methods have O(N) complexity, are compute bound, and require very little synchronization, which makes them a favorable algorithm on next-generation supercomputers. Their most common application is to accelerate N-body…

Numerical Analysis · Computer Science 2012-03-06 Hatem Ltaief , Rio Yokota

We propose XPipe, an efficient asynchronous pipeline model parallelism approach for multi-GPU DNN training. XPipe is designed to use multiple GPUs to concurrently and continuously train different parts of a DNN model. To improve GPU…

Machine Learning · Computer Science 2020-11-10 Lei Guan , Wotao Yin , Dongsheng Li , Xicheng Lu

Large-scale genomic workflows used in precision medicine can process datasets spanning tens to hundreds of gigabytes per sample, leading to high memory spikes, intensive disk I/O, and task failures due to out-of-memory errors. Simple static…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-21 Daniel Mas Montserrat , Ray Verma , Míriam Barrabés , Francisco M. de la Vega , Carlos D. Bustamante , Alexander G. Ioannidis

The apparent stochasticity of in-vivo neural circuits has long been hypothesized to represent a signature of ongoing stochastic inference in the brain. More recently, a theoretical framework for neural sampling has been proposed, which…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Ilja Bytschok , Johannes Bill , Johannes Schemmel , Karlheinz Meier

Computational modeling is becoming a widely used methodology in modern neuroscience. However, as the complexity of the phenomena under study increases, the analysis of the results emerging from the simulations concomitantly becomes more…

Neurons and Cognition · Quantitative Biology 2020-03-16 Sergio E. Galindo , Pablo Toharia , Oscar D. Robles , Eduardo Ros , Luis Pastor , Jesús A. Garrido

Spiking neural networks (SNNs) have demonstrated significant potential in real-time multi-sensor perception tasks due to their event-driven and parameter-efficient characteristics. A key challenge is the timestep-wise iterative update of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jian Song , Xiangfei Yang , Shangke Lyu , Donglin Wang

To train modern large DNN models, pipeline parallelism has recently emerged, which distributes the model across GPUs and enables different devices to process different microbatches in pipeline. Earlier pipeline designs allow multiple…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-23 Ziyue Luo , Xiaodong Yi , Guoping Long , Shiqing Fan , Chuan Wu , Jun Yang , Wei Lin

Modern out-of-order processors have increased capacity to exploit instruction level parallelism (ILP) and memory level parallelism (MLP), e.g., by using wide superscalar pipelines and vector execution units, as well as deep buffers for…

Programming Languages · Computer Science 2018-07-05 Vladimir Kiriansky , Haoran Xu , Martin Rinard , Saman Amarasinghe

We propose a hierarchically modular, dynamical neural network model whose architecture minimizes a specifically designed energy function and defines its temporal characteristics. The model has an internal and an external space that are…

Neurons and Cognition · Quantitative Biology 2026-04-16 Kazuyoshi Tsutsumi , Ernst Niebur

Event-based sensors are well suited for real-time processing due to their fast response times and encoding of the sensory data as successive temporal differences. These and other valuable properties, such as a high dynamic range, are…

Machine Learning · Computer Science 2024-10-10 Mark Schöne , Neeraj Mohan Sushma , Jingyue Zhuge , Christian Mayr , Anand Subramoney , David Kappel
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