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Regularization methods are commonly used in X-ray CT image reconstruction. Different regularization methods reflect the characterization of different prior knowledge of images. In a recent work, a new regularization method called a…

Medical Physics · Physics 2017-04-18 Wenxiang Cong , Ge Wang , Qingsong Yang , Jiang Hsieh , Jia Li , Rongjie Lai

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent machine learning methods for image reconstruction typically involve supervised learning or unsupervised learning,…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Siqi Ye , Zhipeng Li , Michael T. McCann , Yong Long , Saiprasad Ravishankar

A well-known issue of Batch Normalization is its significantly reduced effectiveness in the case of small mini-batch sizes. When a mini-batch contains few examples, the statistics upon which the normalization is defined cannot be reliably…

Machine Learning · Computer Science 2021-03-26 Zhuliang Yao , Yue Cao , Shuxin Zheng , Gao Huang , Stephen Lin

While Model Based Iterative Reconstruction (MBIR) of CT scans has been shown to have better image quality than Filtered Back Projection (FBP), its use has been limited by its high computational cost. More recently, deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2018-12-21 Amirkoushyar Ziabari , Dong Hye Ye , Somesh Srivastava , Ken D. Sauer , Jean-Baptiste Thibault , Charles A. Bouman

Like in many other research fields, recent developments in computational imaging have focused on developing machine learning (ML) approaches to tackle its main challenges. To improve the performance of computational imaging algorithms,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Maximilian B. Kiss , Ander Biguri , Carola-Bibiane Schönlieb , K. Joost Batenburg , Felix Lucka

Sparse-view Computed Tomography (CT) is an emerging protocol designed to reduce X-ray dose radiation in medical imaging. Traditional Filtered Back Projection algorithm reconstructions suffer from severe artifacts due to sparse data. In…

Numerical Analysis · Mathematics 2024-12-03 Elena Loli Piccolomini , Davide Evangelista , Elena Morotti

The iterative refinement method (IRM) has been very successfully applied in many different fields for examples the modern quantum chemical calculation and CT image reconstruction. It is proved that the refinement method can create an exact…

Medical Physics · Physics 2015-12-23 Kang Yang , Kevin Yang , Xintie Yang , Shuang-Ren Zhao

Ultra-low-dose CT (ULDCT) imaging can greatly reduce patient radiation exposure, but the resulting scans suffer from severe structured and random noise that degrades image quality. To address this challenge, we propose a novel Plug-and-Play…

Image and Video Processing · Electrical Eng. & Systems 2026-01-05 Sayantan Dutta , Sudhanya Chatterjee , Ashwini Galande , K. S. Shriram , Bipul Das

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Current self-supervised denoising methods for paired noisy images typically involve mapping one noisy image through the network to the other noisy image. However, after measuring the spectral bias of such methods using our proposed Image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Wang Zhang , Huaqiu Li , Xiaowan Hu , Tao Jiang , Zikang Chen , Haoqian Wang

Neutron computed tomography (nCT) is a 3D characterization technique used to image the internal morphology or chemical composition of samples in biology and materials sciences. A typical workflow involves placing the sample in the path of a…

Positron emission tomography (PET) reconstruction has become an ill-posed inverse problem due to low-count projection data, and a robust algorithm is urgently required to improve imaging quality. Recently, the deep image prior (DIP) has…

Image and Video Processing · Electrical Eng. & Systems 2021-11-01 Chenyu Shen , Wenjun Xia , Hongwei Ye , Mingzheng Hou , Hu Chen , Yan Liu , Jiliu Zhou , Yi Zhang

Low dose X-ray computed tomography (LDCT) is desirable for reduced patient dose. This work develops image reconstruction methods with deep learning (DL) regularization for LDCT. Our methods are based on unrolling of proximal…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Qiaoqiao Ding , Gaoyu Chen , Xiaoqun Zhang , Qiu Huang , Hui Jiand Hao Gao

This work is concerned with applying iterative image reconstruction, based on constrained total-variation minimization, to low-intensity X-ray CT systems that have a high sampling rate. Such systems pose a challenge for iterative image…

Medical Physics · Physics 2016-11-17 Emil Y. Sidky , Rick Chartrand , Yuval Duchin , Christer Ullberg , Xiaochuan Pan

Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…

Medical Physics · Physics 2007-05-23 J. L. Herraiz , S. Espana , J. J. Vaquero , M. Desco , J. M. Udias

Deep-neural-network-based image reconstruction has demonstrated promising performance in medical imaging for under-sampled and low-dose scenarios. However, it requires large amount of memory and extensive time for the training. It is…

Computer Vision and Pattern Recognition · Computer Science 2019-06-12 Dufan Wu , Kyungsang Kim , Quanzheng Li

Total variation (TV) regularization is a popular reconstruction method for ill-posed imaging problems, and particularly useful for applications with piecewise constant targets. However, using TV for medical cone-beam computed X-ray…

Medical Physics · Physics 2024-12-11 Alexander Meaney , Mikael A. K. Brix , Miika T. Nieminen , Samuli Siltanen

We propose a novel dynamic image reconstruction method from PET listmode data that could be particularly suited to tracking single or small numbers of cells. In contrast to conventional PET reconstruction our method combines the information…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Bernhard Schmitzer , Klaus P. Schäfers , Benedikt Wirth

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

We develop and evaluate MlPET, a fast localized machine learning approach for probabilistic PET image analysis addressing the noise-resolution trade-off in conventional reconstructions. MlPET replaces computationally demanding Markov chain…

Medical Physics · Physics 2026-01-27 Thomas Mejer Hansen , Nana Christensen , Mikkel Vendelbo