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X-Ray based computed tomography (CT) is a well-established technique for determining the three-dimensional structure of an object from its two-dimensional projections. In the past few decades, there have been significant advancements in the…

Medical Physics · Physics 2023-04-26 Dinesh Kumar , Dilworth Y. Parkinson , Jeffrey J. Donatelli

Positron emission tomography (PET) is the most sensitive molecular imaging modality routinely applied in our modern healthcare. High radioactivity caused by the injected tracer dose is a major concern in PET imaging and limits its clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuxin Xue , Yige Peng , Lei Bi , Dagan Feng , Jinman Kim

Reconstructing 3D cone beam computed tomography (CBCT) images from a limited set of projections is an important inverse problem in many imaging applications from medicine to inertial confinement fusion (ICF). The performance of traditional…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Xiaojian Xu , Marc Klasky , Michael T. McCann , Jason Hu , Jeffrey A. Fessler

To reduce the potential radiation risk, low-dose CT has attracted much attention. However, simply lowering the radiation dose will lead to significant deterioration of the image quality. In this paper, we propose a noise reduction method…

Medical Physics · Physics 2016-10-04 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Cone Beam Computed Tomography(CBCT) is a now known method to conduct CT imaging. Especially, The Low Dose CT imaging is one of possible options to protect organs of patients when conducting CT imaging. Therefore Low Dose CT imaging can be…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Wooram Kang , Mayank Patwari

Binary Neural Network (BNN) shows its predominance in reducing the complexity of deep neural networks. However, it suffers severe performance degradation. One of the major impediments is the large quantization error between the…

Computer Vision and Pattern Recognition · Computer Science 2020-10-23 Mingbao Lin , Rongrong Ji , Zihan Xu , Baochang Zhang , Yan Wang , Yongjian Wu , Feiyue Huang , Chia-Wen Lin

List-mode positron emission tomography (PET) image reconstruction is an important tool for PET scanners with many lines-of-response and additional information such as time-of-flight and depth-of-interaction. Deep learning is one possible…

Medical Physics · Physics 2024-02-13 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Takashi Isobe , Yasuomi Ouchi

Cone Beam CT plays an important role in many medical fields nowadays, but the potential of this imaging modality is hampered by lower image quality compared to the conventional CT. A lot of recent research has been directed towards…

Medical Physics · Physics 2023-11-01 Nikita Moriakov , Jan-Jakob Sonke , Jonas Teuwen

X-ray computed tomography (CT) reveals the materials' internal structures non-destructively from a tilt series of projected images. Filtered back projection (FBP) is a widely-adopted reconstruction algorithm in CT owing to its small…

Low-Dose Computed Tomography (LDCT) technique, which reduces the radiation harm to human bodies, is now attracting increasing interest in the medical imaging field. As the image quality is degraded by low dose radiation, LDCT exams require…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Liutao Yang , Zhongnian Li , Rongjun Ge , Junyong Zhao , Haipeng Si , Daoqiang Zhang

Limited data and low dose constraints are common problems in a variety of tomographic reconstruction paradigms which lead to noisy and incomplete data. Over the past few years sinogram denoising has become an essential pre-processing step…

Computer Vision and Pattern Recognition · Computer Science 2016-03-15 Faisal Mahmood , Nauman Shahid , Pierre Vandergheynst , Ulf Skoglund

Cone-beam tomography enables rapid 3D acquisitions, making it a suitable imaging modality for dental imaging. However, as with all X-ray techniques, the main challenge is to reduce the dose while maintaining good image quality. Moreover,…

Signal Processing · Electrical Eng. & Systems 2024-12-24 Louise Friot--Giroux , Françoise Peyrin , Voichiţa Maxim

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

Repeated computed tomography (CT) scans are required in some clinical applications such as image-guided radiotherapy and follow-up observations over a time period. To optimize the radiation dose utility, a normal-dose (or full-dose) CT scan…

Medical Physics · Physics 2017-02-23 Hao Zhang , Jianhua Ma , William Moore , Zhengrong Liang

Cone beam computed tomography (CBCT) has been widely used in clinical practice, especially in dental clinics, while the radiation dose of X-rays when capturing has been a long concern in CBCT imaging. Several research works have been…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Yu Fang , Lanzhuju Mei , Changjian Li , Yuan Liu , Wenping Wang , Zhiming Cui , Dinggang Shen

Bilinear models that decompose dynamic data to spatial and temporal factors are powerful and memory-efficient tools for the recovery of dynamic MRI data. These methods rely on sparsity and energy compaction priors on the factors to…

Image and Video Processing · Electrical Eng. & Systems 2021-07-01 Abdul Haseeb Ahmed , Prashant Nagpal , Mathews Jacob

While model-based reconstruction methods have been successfully applied to flat-panel cone-beam CT (FP-CBCT) systems, typical implementations ignore both spatial correlations in the projection data as well as system blurs due to the…

Medical Physics · Physics 2017-06-20 Steven Tilley , Jeffrey H. Siewerdsen , J. Webster Stayman

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

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