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Since clinical letters contain sensitive information, clinical-related datasets can not be widely applied in model training, medical research, and teaching. This work aims to generate reliable, various, and de-identified synthetic clinical…

Computation and Language · Computer Science 2024-09-17 Libo Ren , Samuel Belkadi , Lifeng Han , Warren Del-Pinto , Goran Nenadic

Large language models trained on clinical text risk exposing sensitive patient information, yet differential privacy (DP) methods often severely degrade the diagnostic accuracy needed for deployment. Despite rapid progress in DP…

Machine Learning · Computer Science 2025-11-20 Mathieu Dufour , Andrew Duncan

Large, human-annotated datasets are central to the development of natural language processing models. Collecting these datasets can be the most challenging part of the development process. We address this problem by introducing a general…

Computation and Language · Computer Science 2020-04-29 Alana Marzoev , Samuel Madden , M. Frans Kaashoek , Michael Cafarella , Jacob Andreas

Unstructured textual data is at the heart of healthcare systems. For obvious privacy reasons, these documents are not accessible to researchers as long as they contain personally identifiable information. One way to share this data while…

Cryptography and Security · Computer Science 2022-11-03 Yakini Tchouka , Jean-François Couchot , David Laiymani

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

In the current data driven era, synthetic data, artificially generated data that resembles the characteristics of real world data without containing actual personal information, is gaining prominence. This is due to its potential to…

Machine Learning · Computer Science 2023-09-06 Tshilidzi Marwala , Eleonore Fournier-Tombs , Serge Stinckwich

Synthetic data has the potential to improve the performance, training efficiency, and privacy of real training examples. Nevertheless, existing approaches for synthetic text generation are mostly heuristics and cannot generate…

Machine Learning · Computer Science 2025-06-10 Dang Nguyen , Zeman Li , Mohammadhossein Bateni , Vahab Mirrokni , Meisam Razaviyayn , Baharan Mirzasoleiman

Each year, hundreds of clinical trials are conducted to evaluate new medical interventions, but sharing patient records from these trials with other institutions can be challenging due to privacy concerns and federal regulations. To help…

Machine Learning · Computer Science 2025-02-19 Trisha Das , Zifeng Wang , Afrah Shafquat , Mandis Beigi , Jason Mezey , Jacob Aptekar , Jimeng Sun

This paper studies the use of language models as a source of synthetic unlabeled text for NLP. We formulate a general framework called ``generate, annotate, and learn (GAL)'' to take advantage of synthetic text within knowledge…

Machine Learning · Computer Science 2022-06-01 Xuanli He , Islam Nassar , Jamie Kiros , Gholamreza Haffari , Mohammad Norouzi

De-identification in the healthcare setting is an application of NLP where automated algorithms are used to remove personally identifying information of patients (and, sometimes, providers). With the recent rise of generative large language…

Computation and Language · Computer Science 2025-09-19 Kiana Aghakasiri , Noopur Zambare , JoAnn Thai , Carrie Ye , Mayur Mehta , J. Ross Mitchell , Mohamed Abdalla

Accurate and comprehensive clinical documentation is crucial for delivering high-quality healthcare, facilitating effective communication among providers, and ensuring compliance with regulatory requirements. However, manual transcription…

Computation and Language · Computer Science 2024-06-12 Anjanava Biswas , Wrick Talukdar

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

Synthetic data generation is gaining increasing popularity in different computer vision applications. Existing state-of-the-art face recognition models are trained using large-scale face datasets, which are crawled from the Internet and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Hatef Otroshi Shahreza , Sébastien Marcel

Clinical free-text data offers immense potential to improve population health research such as richer phenotyping, symptom tracking, and contextual understanding of patient care. However, these data present significant privacy risks due to…

Clinician notes are a rich source of patient information but often contain inconsistencies due to varied writing styles, colloquialisms, abbreviations, medical jargon, grammatical errors, and non-standard formatting. These inconsistencies…

Computation and Language · Computer Science 2025-01-03 Daniel B. Hier , Michael D. Carrithers , Thanh Son Do , Tayo Obafemi-Ajayi

Objective The evaluation of natural language processing (NLP) models for clinical text de-identification relies on the availability of clinical notes, which is often restricted due to privacy concerns. The NLP Sandbox is an approach for…

Private synthetic data sharing is preferred as it keeps the distribution and nuances of original data compared to summary statistics. The state-of-the-art methods adopt a select-measure-generate paradigm, but measuring large domain…

Cryptography and Security · Computer Science 2023-10-11 Meifan Zhang , Dihang Deng , Lihua Yin

Patient notes contain a wealth of information of potentially great interest to medical investigators. However, to protect patients' privacy, Protected Health Information (PHI) must be removed from the patient notes before they can be…

Computation and Language · Computer Science 2016-11-01 Ji Young Lee , Franck Dernoncourt , Ozlem Uzuner , Peter Szolovits

Access to real-world medical data is often restricted due to privacy regulations, posing a significant barrier to the advancement of healthcare research. Synthetic data offers a promising alternative; however, generating realistic,…

Artificial Intelligence · Computer Science 2025-08-13 Arshia Ilaty , Hossein Shirazi , Hajar Homayouni
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