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Machine learning (ML) models frequently rely on training data that may include sensitive or personal information, raising substantial privacy concerns. Legislative frameworks such as the General Data Protection Regulation (GDPR) and the…

Machine Learning · Computer Science 2024-12-31 Md Mahadi Hasan Nahid , Sadid Bin Hasan

Protecting patient privacy in clinical narratives is essential for enabling secondary use of healthcare data under regulations such as GDPR and HIPAA. While manual de-identification remains the gold standard, it is costly and slow,…

Cryptography and Security · Computer Science 2026-04-24 Michele Miranda , Xinlan Yan , Nishant Mishra , Rachel Murphy , Ameen Abu-Hanna , Sébastien Bratières , Iacer Calixto

Service providers of large language model (LLM) applications collect user instructions in the wild and use them in further aligning LLMs with users' intentions. These instructions, which potentially contain sensitive information, are…

Cryptography and Security · Computer Science 2024-07-03 Da Yu , Peter Kairouz , Sewoong Oh , Zheng Xu

Natural Language Processing (NLP) has undergone transformative changes with the advent of deep learning methodologies. One challenge persistently confronting researchers is the scarcity of high-quality, annotated datasets that drive these…

Computation and Language · Computer Science 2023-10-13 Sia Gholami , Marwan Omar

Despite advances in machine learning (ML) and large language models (LLMs), rule-based natural language processing (NLP) systems remain active in clinical settings due to their interpretability and operational efficiency. However, their…

Computation and Language · Computer Science 2025-06-23 Jianlin Shi , Brian T. Bucher

Machine learning heavily relies on data, but real-world applications often encounter various data-related issues. These include data of poor quality, insufficient data points leading to under-fitting of machine learning models, and…

Machine Learning · Computer Science 2025-04-07 Yingzhou Lu , Lulu Chen , Yuanyuan Zhang , Minjie Shen , Huazheng Wang , Xiao Wang , Capucine van Rechem , Tianfan Fu , Wenqi Wei

Obtaining text datasets with semantic annotations is an effortful process, yet crucial for supervised training in natural language processsing (NLP). In general, developing and applying new NLP pipelines in domain-specific contexts for…

Computation and Language · Computer Science 2022-09-01 Johann Frei , Frank Kramer

Large language models (LLMs) have emerged as a powerful tool for synthetic data generation. A particularly important use case is producing synthetic replicas of private text, which requires carefully balancing privacy and utility. We…

Cryptography and Security · Computer Science 2026-04-14 Qian Ma , Sarah Rajtmajer

Free-text clinical notes detail all aspects of patient care and have great potential to facilitate quality improvement and assurance initiatives as well as advance clinical research. However, concerns about patient privacy and…

Computation and Language · Computer Science 2021-02-23 Nicholas Dobbins , David Wayne , Kahyun Lee , Özlem Uzuner , Meliha Yetisgen

This work investigates the effectiveness of different pseudonymization techniques, ranging from rule-based substitutions to using pre-trained Large Language Models (LLMs), on a variety of datasets and models used for two widely used NLP…

Computation and Language · Computer Science 2023-06-12 Oleksandr Yermilov , Vipul Raheja , Artem Chernodub

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

De-identification is the process of removing 18 protected health information (PHI) from clinical notes in order for the text to be considered not individually identifiable. Recent advances in natural language processing (NLP) has allowed…

Computation and Language · Computer Science 2018-10-04 Kaung Khin , Philipp Burckhardt , Rema Padman

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

Synthetic clinical data are increasingly important for advancing AI in healthcare, given strict privacy constraints on real-world EHRs, limited availability of annotated rare-condition data, and systemic biases in observational datasets.…

Machine Learning · Computer Science 2025-09-16 Rumeng Li , Xun Wang , Hong Yu

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

Machine Learning · Computer Science 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

Access to large-scale high-quality healthcare databases is key to accelerate medical research and make insightful discoveries about diseases. However, access to such data is often limited by patient privacy concerns, data sharing…

Deep neural networks have become prevalent in human analysis, boosting the performance of applications, such as biometric recognition, action recognition, as well as person re-identification. However, the performance of such networks scales…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Indu Joshi , Marcel Grimmer , Christian Rathgeb , Christoph Busch , Francois Bremond , Antitza Dantcheva

A variety of methods existing for generating synthetic electronic health records (EHRs), but they are not capable of generating unstructured text, like emergency department (ED) chief complaints, history of present illness or progress…

Computation and Language · Computer Science 2018-12-18 Scott Lee

Institutions collect massive learning traces but they may not disclose it for privacy issues. Synthetic data generation opens new opportunities for research in education. In this paper we present a generative model for educational data that…

Computers and Society · Computer Science 2022-07-09 Jill-Jênn Vie , Tomas Rigaux , Sein Minn