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Widely used models in genetics include the Wright-Fisher diffusion and its moment dual, Kingman's coalescent. Each has a multilocus extension but under neither extension is the sampling distribution available in closed-form, and their…

Probability · Mathematics 2015-06-24 Paul A. Jenkins , Paul Fearnhead , Yun S. Song

We study stochastic evolutionary game dynamics in a population of finite size. Individuals in the population are divided into two dynamically evolving groups. The structure of the population is formally described by a Wright-Fisher type…

Probability · Mathematics 2020-07-01 Timothy Chumley , Ozgur Aydogmus , Anastasios Matzavinos , Alexander Roitershtein

Moran or Wright-Fisher processes are probably the most well known model to study the evolution of a population under various effects. Our object of study will be the Simpson index which measures the level of diversity of the population, one…

Probability · Mathematics 2018-09-25 Arnaud Personne , Arnaud Guillin , Franck Jabot , Arnaud Guillin

Several groups have recently modeled evolutionary transitions from an ancestral allele to a beneficial allele separated by one or more intervening mutants. The beneficial allele can become fixed if a succession of intermediate mutants are…

Populations and Evolution · Quantitative Biology 2011-07-14 Stephen R Proulx

We study a family of n-dimensional diffusions, taking values in the unit simplex of vectors with nonnegative coordinates that add up to one. These processes satisfy stochastic differential equations which are similar to the ones for the…

Probability · Mathematics 2013-03-15 Soumik Pal

In a (two-type) Wright-Fisher diffusion with directional selection and two-way mutation, let $x$ denote today's frequency of the beneficial type, and given $x$, let $h(x)$ be the probability that, among all individuals of today's…

Populations and Evolution · Quantitative Biology 2015-07-10 Ute Lenz , Sandra Kluth , Ellen Baake , Anton Wakolbinger

We study a generalization of the Wright--Fisher model in which some individuals adopt a behavior that is harmful to others without any direct advantage for themselves. This model is motivated by studies of spiteful behavior in nature,…

Probability · Mathematics 2015-03-18 Ludovic Goudenège , Pierre-André Zitt

The Wright-Fisher diffusion is a fundamentally important model of evolution encompassing genetic drift, mutation, and natural selection. Suppose you want to infer the parameters associated with these processes from an observed sample path.…

Statistics Theory · Mathematics 2024-10-22 Paul A. Jenkins

We study voter models defined on large sets. Through a perspective emphasizing the martingale property of voter density processes, we prove that in general, their convergence to the Wright-Fisher diffusion only involves certain averages of…

Probability · Mathematics 2013-11-25 Yu-Ting Chen , Jihyeok Choi , J. Theodore Cox

A generalised one-dimensional Fisher-Wright diffusion process with mutations is considered. This is a well-known model in population genetics. An exponential recurrence is established for the process, which also implies an exponential rate…

Probability · Mathematics 2025-03-27 Roman Sineokiy , Alexander Veretennikov

We provide a general theorem bounding the error in the approximation of a random measure of interest--for example, the empirical population measure of types in a Wright-Fisher model--and a Dirichlet process, which is a measure having…

Probability · Mathematics 2020-07-07 Han L. Gan , Nathan Ross

We investigate spatial evolutionary games with death-birth updating in large finite populations. Within growing spatial structures subject to appropriate conditions, the density processes of a fixed type are proven to converge to the…

Probability · Mathematics 2017-05-23 Yu-Ting Chen

Coupled Wright-Fisher diffusions have been recently introduced to model the temporal evolution of finitely-many allele frequencies at several loci. These are vectors of multidimensional diffusions whose dynamics are weakly coupled among…

Probability · Mathematics 2026-01-07 Chiara Boetti , Matteo Ruggiero

Duality plays an important role in population genetics. It can relate results from forwards-in-time models of allele frequency evolution with those of backwards-in-time genealogical models; a well known example is the duality between the…

Populations and Evolution · Quantitative Biology 2019-08-09 Robert C. Griffiths , Paul A. Jenkins , Sabin Lessard

We consider the classical Wright-Fisher model with mutation and selection. Mutations occur independently in each locus, and selection is performed according to the sharp peak landscape. In the asymptotic regime studied in [3], a…

Probability · Mathematics 2014-03-28 Joseba Dalmau

We study the large population limit of a multi-strategy discrete-time Moran process in the weak selection regime. We show that the replicator dynamics is interpreted as the large-population limit of the Moran process. This result is…

Analysis of PDEs · Mathematics 2025-01-23 Marco Morandotti , Gianluca Orlando

In this paper an exact rejection algorithm for simulating paths of the coupled Wright-Fisher diffusion is introduced. The coupled Wright-Fisher diffusion is a family of multidimensional Wright-Fisher diffusions that have drifts depending on…

Probability · Mathematics 2020-09-08 Celia García-Pareja , Henrik Hult , Timo Koski

Evolutionary models for populations of constant size are frequently studied using the Moran model, the Wright-Fisher model, or their diffusion limits. When evolution is neutral, a random genealogy given through Kingman's coalescent is used…

Populations and Evolution · Quantitative Biology 2012-07-31 Peter Pfaffelhuber , Benedikt Vogt

The goal of this paper is to develop a theory of graphon-valued stochastic processes, and to construct and analyse a natural class of such processes arising from population genetics. We consider finite populations where individuals change…

Probability · Mathematics 2019-08-20 Siva Athreya , Frank den Hollander , Adrian Röllin

We consider diffusion processes x_{t} on the unit interval. Doob-transformation techniques consist of a selection of x_{t}-paths procedure. The law of the transformed process is the one of a branching diffusion system of particles, each…

Quantitative Methods · Quantitative Biology 2011-07-15 Thierry Huillet