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In research activities regarding Magnetic Resonance Imaging in medicine, simulation tools with a universal approach are rare. Usually, simulators are developed and used which tend to be restricted to a particular, small range of…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-05-30 Jürgen Kürsch

This paper studies linear reconstruction of partially observed functional data which are recorded on a discrete grid. We propose a novel estimation approach based on approximate factor models with increasing rank taking into account…

Statistics Theory · Mathematics 2024-05-22 Maximilian Ofner , Siegfried Hörmann

From the optimization point of view, a difficulty with parallel MRI with simultaneous coil sensitivity estimation is the multiplicative nature of the non-linear forward operator: the image being reconstructed and the coil sensitivities…

Numerical Analysis · Mathematics 2018-02-06 Yonggui Zhu , Tuomo Valkonen

Typical quantitative MRI (qMRI) methods estimate parameter maps in a two-step pipeline that first reconstructs images from undersampled k-space data and then performs model fitting, which is prone to biases and error propagation. We propose…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Xinrui Jiang , Yohan Jun , Jaejin Cho , Mengze Gao , Xingwang Yong , Berkin Bilgic

Magnetic resonance fingerprinting (MRF) can successfully recover quantitative multi-parametric maps of human tissue in a very short acquisition time. Due to their pseudo-random nature, the large spatial undersampling artifacts can be…

In this article, we propose a novel regularization method for a class of nonlinear inverse problems that is inspired by an application in quantitative magnetic resonance imaging (qMRI). The latter is a special instance of a general…

Optimization and Control · Mathematics 2025-06-16 Guozhi Dong , Michael Hintermüller , Clemens Sirotenko

Conventional Magnetic Resonance Imaging (MRI) is hampered by long scan times and only qualitative image contrasts that prohibit a direct comparison between different systems. To address these limitations, model-based reconstructions…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Xiaoqing Wang , Zhengguo Tan , Nick Scholand , Volkert Roeloffs , Martin Uecker

Purpose: Recent developments in hardware design enable the use of Fast Field-Cycling (FFC) techniques in MRI to exploit the different relaxation rates at very low field strength, achieving novel contrast. The method opens new avenues for in…

Signal Processing · Electrical Eng. & Systems 2021-05-19 Markus Bödenler , Oliver Maier , Rudolf Stollberger , Lionel M. Broche , P. James Ross , Mary-Joan MacLeod , Hermann Scharfetter

Mathematical models are becoming increasingly important in magnetic resonance imaging (MRI), as they provide a mechanistic approach for making a link between tissue microstructure and signals acquired using the medical imaging instrument.…

Medical Physics · Physics 2021-06-10 Viktor Vegh , Shahrzad Moinian , Qianqian Yang , David C. Reutens

Real-time magnetic resonance imaging (MRI) methods generally shorten the measuring time by acquiring less data than needed according to the sampling theorem. In order to obtain a proper image from such undersampled data, the reconstruction…

Numerical Analysis · Mathematics 2013-12-05 Housen Li , Markus Haltmeier , Shuo Zhang , Jens Frahm , Axel Munk

Psychiatric neuroscience is increasingly aware of the need to define psychopathology in terms of abnormal neural computation. The central tool in this endeavour is the fitting of computational models to behavioural data. The most prominent…

Quantitative Methods · Quantitative Biology 2018-03-28 Abraham Nunes , Alexander Rudiuk

A computer code is written that simulates the relaxation back to thermal equilibrium of an ensemble of particles after a pi/2 pulse. Beginning with Bloch's equations the exponential relaxation behavior is discussed and the transition into a…

Medical Physics · Physics 2007-05-23 John L. Haller

Compressed sensing takes advantage of low-dimensional signal structure to reduce sampling requirements far below the Nyquist rate. In magnetic resonance imaging (MRI), this often takes the form of sparsity through wavelet transform, finite…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jonathan I. Tamir , Frank Ong , Suma Anand , Ekin Karasan , Ke Wang , Michael Lustig

We propose an unsupervised convolutional neural network (CNN) for relaxation parameter estimation. This network incorporates signal relaxation and Bloch simulations while taking advantage of residual learning and spatial relations across…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Mengze Gao , Huihui Ye , Tae Hyung Kim , Zijing Zhang , Seohee So , Berkin Bilgic

Quantitative MRI methods that estimate multiple physical parameters simultaneously often require the fitting of a computational complex signal model defined through the Bloch equations. Repeated Bloch simulations can be avoided by matching…

Signal Processing · Electrical Eng. & Systems 2019-11-19 Willem van Valenberg , Stefan Klein , Frans M. Vos , Kirsten Koolstra , Lucas J. van Vliet , Dirk H. J. Poot

The simulation of chemistry is among the most promising applications of quantum computing. However, most prior work exploring algorithms for block-encoding, time-evolving, and sampling in the eigenbasis of electronic structure Hamiltonians…

In this paper, we propose the use of Recurrent Inference Machines (RIMs) to perform T1 and T2 mapping. The RIM is a neural network framework that learns an iterative inference process based on the signal model, similar to conventional…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 E. R. Sabidussi , S. Klein , M. W. A. Caan , S. Bazrafkan , A. J. den Dekker , J. Sijbers , W. J. Niessen , D. H. J. Poot

Modeling quantum many-body systems is enormously challenging due to the exponential scaling of Hilbert dimension with system size. Finding efficient compressions of the wavefunction is key to building scalable models. Here, we introduce…

Computational Physics · Physics 2020-03-16 Christopher Roth

We introduce FB-LISA, a forward-backward (FB) generalization of a recently proposed line-search-based stochastic gradient algorithm to address the imaging problem of volumetric reconstruction in Computed Tomography, a substantially high…

Numerical Analysis · Mathematics 2026-05-13 Tatiana A. Bubba , Elena Morotti , Federica Porta , Valeria Ruggiero , Ilaria Trombini

Quantum simulators have made a remarkable progress towards exploring the dynamics of many-body systems, many of which offer a formidable challenge to both theoretical and numerical methods. While state-of-the-art quantum simulators are in…