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Quantum metrology enables some of the most precise measurements. In the life sciences, diamond-based quantum sensing has enabled a new class of biophysical sensors and diagnostic devices that are being investigated as a platform for cancer…
Single-molecule fluorescence techniques provide exceptional sensitivity to probe biomolecular interactions. However, their application to accurately quantify analytes at the picomolar concentrations relevant for biosensing remains…
We report on the characterization of a superconducting nanowire detector for ions at low kinetic energies. We measure the absolute single particle detection efficiency $\eta$ and trace its increase with energy up to $\eta = 100$ %. We…
Detecting and characterizing decoherence-inducing noise sources is critical for developing robust quantum technologies and deploying quantum sensors operating at molecular scales. However, current noise spectroscopies rely on severe…
One of the most fundamental quantum states of light is squeezed vacuum, in which noise in one of the quadratures is less than the standard quantum noise limit. Significant progress has been made in the generation of optical squeezed vacuum…
Lab on a chip (LOC) device intakes fluid and makes it flow through the microchannels, to achieve rapid, highly sensitive and low-cost analysis with significant yield. Graphene has vast potential to be used in LOC devices owing to its…
We have designed optical metasurfaces hosting high-quality factor quasi-bound state in the continuum (q-BIC) resonances for optical biosensing in flow. The unit cell of the metasurface contains two rectangular bars. An asymmetry factor is…
In the last few decades, the development of miniature biological sensors that can detect and measure different phenomena at the nanoscale has led to transformative disease diagnosis and treatment techniques. Among others, biofunctional…
X-ray nanotomography is a powerful tool for the characterization of nanoscale materials and structures, but is difficult to implement due to competing requirements on X-ray flux and spot size. Due to this constraint, state-of-the-art…
Quantum sensing takes advantage of well controlled quantum systems for performing measurements with high sensitivity and precision. We have implemented a concept for quantum sensing with arbitrary frequency resolution, independent of the…
The ability to detect and size individual nanoparticles with high resolution is crucial to understanding behaviours of single particles and effectively using their strong size-dependent properties to develop innovative products. We report…
Quantum sensors hold considerable promise for precision measurement, yet their capabilities are inherently constrained by environmental noise. A fundamental task in quantum sensing is determining the precision limit of noisy sensor devices.…
Electrochemical biosensors and the related concept of redox detection at nanogap electrodes are increasingly explored for ultra-sensitive detection of biomolecules. While experimental demonstrations have been encouraging, the associated…
Integrating the scalability of individually addressable arrays of optical-tweezer-trapped single atoms with the efficient light-matter interface provided by nanophotonic waveguides has been a long-standing challenge in quantum technologies…
Nanoparticle metrology has long been constrained by the assumption that, in mixed and unprocessed fluids, particle size, morphology, composition, and species-specific abundance cannot be resolved simultaneously from a single label-free…
The combination of microwave and microfluidic technologies has the potential to enable wireless monitoring and interaction with bioparticles, facilitating in this way the exploration of a still largely uncharted territory at the…
A traditional heterodyne detector, as a phase-insensitive device, suffers the well-known 3 dB noise penalty caused by image sideband vacuum. In contrast, a heterodyne detector with a bichromatic local oscillator, as a phase-sensitive…
We perform balanced homodyne detection of the electromagnetic field in a single-mode tapered optical nanofiber surrounded by rubidium atoms in a magneto-optical trap. Resonant fluorescence of atoms into the nanofiber mode manifests itself…
Optical fibers are crucial for guiding light in various sensing applications. Especially for quantum sensors such as the nitrogen-vacancy (NV) center in diamond, they enable light control and device miniaturization. However, fluorescence…
We demonstrate a high-purity source of indistinguishable single photons using a quantum dot embedded in a nanophotonic waveguide. The source features a near-unity internal coupling efficiency and the collected photons are efficiently…