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Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

Microplastics are increasingly recognized as a global environmental health threat, yet their detection and characterization remain constrained by the cost, form factor, and throughput of existing analytical tools. Portable…

Applied Physics · Physics 2025-10-31 Sayedus Salehin , Syed Shaheer Uddin Ahmed , Uzay Tefek , Laura Weirauch , M. Selim Hanay

Nuclei instance segmentation is an essential task in pathology image analysis, serving as the foundation for many downstream applications. The release of several public datasets has significantly advanced research in this area, yet many…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Jin Tae Kwak

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yan Wang , Xu Wei , Fengze Liu , Jieneng Chen , Yuyin Zhou , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Brain plays a crucial role in regulating body functions and cognitive processes, with brain tumors posing significant risks to human health. Precise and prompt detection is a key factor in proper treatment and better patient outcomes.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Roham Maiti , Debasmita Bhoumik

We introduce the Normalized Matching Transformer (NMT), a deep learning approach for efficient and accurate sparse semantic keypoint matching between image pairs. NMT consists of a strong visual backbone, geometric feature refinement via…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Abtin Pourhadi , Paul Swoboda

A high precision method to determine fusion in the capture of $\alpha$-particles by nuclei is presented. For $\alpha$-capture by $^{40}{\rm Ca}$ and $^{44}{\rm Ca}$, such an approach gives (1) the parameters of the $\alpha$--nucleus…

Nuclear Theory · Physics 2015-04-21 Sergei P. Maydanyuk , Peng-Ming Zhang , Sergei V. Belchikov

The realm of medical image diagnosis has advanced significantly with the integration of computer-aided diagnosis and surgical systems. However, challenges persist, particularly in achieving precise image segmentation. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Mutyyba Asghar , Ahmad Raza Shahid , Akhtar Jamil , Kiran Aftab , Syed Ather Enam

Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Reza Babaei , Samuel Cheng , Theresa Thai , Shangqing Zhao

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

Quantitative Methods · Quantitative Biology 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

Modern histopathological image analysis relies on the segmentation of cell structures to derive quantitative metrics required in biomedical research and clinical diagnostics. State-of-the-art deep learning approaches predominantly apply…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Yoav Alon , Huiyu Zhou

Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to late diagnosis and extensive heterogeneity across subtypes. Current diagnostic methods are limited in their ability to reveal underlying genomic…

Image and Video Processing · Electrical Eng. & Systems 2025-11-06 Gabriela Fernandes

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zunaira Rauf , Abdul Rehman Khan , Asifullah Khan

Microorganisms play a vital role in human life. Therefore, microorganism detection is of great significance to human beings. However, the traditional manual microscopic detection methods have the disadvantages of long detection cycle, low…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Pingli Ma , Chen Li , Md Mamunur Rahaman , Yudong Yao , Jiawei Zhang , Shuojia Zou , Xin Zhao , Marcin Grzegorzek

Neuromorphic processors improve the efficiency of machine learning algorithms through the implementation of physical artificial neurons to perform computations. However, whilst efficient classical neuromorphic processors have been…

Quantum Physics · Physics 2025-04-03 Sam Nerenberg , Oliver D. Neill , Giulia Marcucci , Daniele Faccio

In standard hospital blood tests, the traditional process requires doctors to manually isolate leukocytes from microscopic images of patients' blood using microscopes. These isolated leukocytes are then categorized via automatic leukocyte…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Yifei Chen , Chenyan Zhang , Ben Chen , Yiyu Huang , Yifei Sun , Changmiao Wang , Xianjun Fu , Yuxing Dai , Feiwei Qin , Yong Peng , Yu Gao