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Fluorescence Molecular Tomography (FMT) is a promising technique for non-invasive 3D visualization of fluorescent probes, but its reconstruction remains challenging due to the inherent ill-posedness and reliance on inaccurate or…

Image and Video Processing · Electrical Eng. & Systems 2025-11-07 Shihan Zhao , Jianru Zhang , Yanan Wu , Linlin Li , Siyuan Shen , Xingjun Zhu , Guoyan Zheng , Jiahua Jiang , Wuwei Ren

The segmentation module which precisely outlines the nodules is a crucial step in a computer-aided diagnosis(CAD) system. The most challenging part of such a module is how to achieve high accuracy of the segmentation, especially for the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Xinliang Fu , Jiayin Zheng , Juanyun Mai , Yanbo Shao , Minghao Wang , Linyu Li , Zhaoqi Diao , Yulong Chen , Jianyu Xiao , Jian You , Airu Yin , Yang Yang , Xiangcheng Qiu , Jinsheng Tao , Bo Wang , Hua Ji

Accurate detection and segmentation of anatomical structures from ultrasound images are crucial for clinical diagnosis and biometric measurements. Although ultrasound imaging has been widely used with superiorities such as low cost and…

Computer Vision and Pattern Recognition · Computer Science 2016-07-08 Hao Chen , Yefeng Zheng , Jin-Hyeong Park , Pheng-Ann Heng , S. Kevin Zhou

Ophthalmic diseases represent a significant global health issue, necessitating the use of advanced precise diagnostic tools. Optical Coherence Tomography (OCT) imagery which offers high-resolution cross-sectional images of the retina has…

Artificial Intelligence · Computer Science 2024-09-27 Md. Touhidul Islam , Md. Abtahi Majeed Chowdhury , Mahmudul Hasan , Asif Quadir , Lutfa Aktar

Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in living cells and to observe them…

Automated cervical nucleus segmentation based on deep learning can effectively improve the quantitative analysis of cervical cancer. However, accurate nuclei segmentation is still challenging. The classic U-net has not achieved satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2019-11-13 Jie Zhao , Lei Dai , Mo Zhang , Fei Yu , Meng Li , Hongfeng Li , Wenjia Wang , Li Zhang

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Background: Image analysis applications in digital pathology include various methods for segmenting regions of interest. Their identification is one of the most complex steps, and therefore of great interest for the study of robust methods…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Giuseppe Giacopelli , Michele Migliore , Domenico Tegolo

We report on a new algorithm for detection of crystallographic information in 3D, as retained in Atom Probe Tomography (APT), with improved robustness and signal detection performance. The algorithm is underpinned by 1D distribution…

Materials Science · Physics 2019-05-22 Daniel Haley , Paul A. J. Bagot , Michael P. Moody

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

To operate quantum sensors at their quantum limit in real time, it is crucial to identify efficient data inference tools for rapid parameter estimation. In photodetection, the key challenge is the fast interpretation of click-patterns that…

Quantum Physics · Physics 2026-02-24 Mateusz Molenda , Lewis A. Clark , Marcin Płodzień , Jan Kolodynski

Several statistical approaches based on reproducing kernels have been proposed to detect abrupt changes arising in the full distribution of the observations and not only in the mean or variance. Some of these approaches enjoy good…

Statistics Theory · Mathematics 2017-10-13 Alain Celisse , Guillemette Marot , Morgane Pierre-Jean , Guillem Rigaill

This work seeks to determine how modern machine learning techniques may be applied to the previously unexplored topic of melanoma diagnostics using digital pathology. We curated a new dataset of 50 patient cases of cutaneous melanoma using…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Adon Phillips , Iris Teo , Jochen Lang

The difficulty of detecting mitosis and its similarity to non-mitosis objects has remained a challenge in computational pathology. The lack of publicly available data has added more complexity. Deep learning algorithms have shown potentials…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Seyed H. Mirjahanmardi , Samir Mitha , Salar Razavi , Susan Done , April Khademi

Ptychography has become prominent at synchrotron facilities worldwide for characterizing biological and material specimens' topological structures and properties at the nanometer or atomic scale, due to its lens - less, highly quantitative…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Tao Liu , Bingyang Wang , JiangTao Zhao , Maik Kahnt , Fucai Zhang

We present an algorithm for multi-scale tumor (chimeric cell) detection in high resolution slide scans. The broad range of tumor sizes in our dataset pose a challenge for current Convolutional Neural Networks (CNN) which often fail when…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Qingchao Zhang , Coy D. Heldermon , Corey Toler-Franklin

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…

Interferometric closure invariants encode calibration-independent details of an object's morphology. Excepting simple cases, a direct backward transformation from closure invariants to morphologies is not well established. We demonstrate…

Instrumentation and Methods for Astrophysics · Physics 2024-08-27 Nithyanandan Thyagarajan , Lucas Hoefs , O. Ivy Wong

Acute lymphoblastic leukemia (ALL) is the most malignant form of leukemia and the most common cancer in adults and children. Traditionally, leukemia is diagnosed by analyzing blood and bone marrow smears under a microscope, with additional…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Maksuda Akter , Rabea Khatun , Md Manowarul Islam

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning
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