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Advances in optical imaging always look for an increase in sensitivity and resolution among other practicability aspects. Within the same scope, in this work we report a versatile interference contrast imaging technique, capable of sub-nm…

Deconvolution phase microscopy enables high-contrast visualization of transparent samples through reconstructions of their transmitted phases or refractive indexes. Herein, we propose a method to extend 2D deconvolution phase microscopy to…

Optics · Physics 2022-04-20 Herve Hugonnet , Mahn Jae Lee , Yongkeun Park

Quantum imaging with undetected light (QIUL) can retrieve amplitude and phase information of an object by exploiting the quantum correlations of photon-pairs generated through spontaneous parametric down conversion (SPDC), where the…

There is a need for a cost-effective, quantitative imaging tool that can be deployed endoscopically to better detect early stage gastrointestinal cancers. Spatial frequency domain imaging (SFDI) is a low-cost imaging technique that produces…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Jane Crowley , George S. D. Gordon

We present a powerful and cost-effective method for active illumination using a digital micromirror device (DMD) for quantitative phase imaging techniques. Displaying binary illumination patterns on a DMD with appropriate spatial filtering,…

Optics · Physics 2023-07-19 Seungwoo Shin , Kyoohyun Kim , Jonghee Yoon , YongKeun Park

Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…

Three-dimensional molecular imaging of living cells is essential for unraveling cellular metabolism and response to therapies. However, existing volumetric methods, including fluorescence microscopy and quantitative phase imaging, either…

Quantum metrology exploits quantum correlations to make precise measurements with limited particle numbers. By utilizing inter- and intra- mode correlations in an optical interferometer, we find a state that combines entanglement and…

Quantum Physics · Physics 2016-04-21 P. A. Knott , T. J. Proctor , A. J. Hayes , J. P. Cooling , J. A. Dunningham

Imaging transparent samples remains an ongoing challenge in the study of unstained biological cells and material samples. Widely used methods trade off system complexity, cost and bulk, computational efficiency and information content. Here…

The recent introduction of coherent optical communications has created a compelling need for ultra-fast phase-sensitive measurement techniques operating at milliwatt peak power levels and in time scales ranging from sub-picoseconds to…

Real-time monitoring of functional tissue parameters, such as local blood oxygenation, based on optical imaging could provide groundbreaking advances in the diagnosis and interventional therapy of various diseases. While photoacoustic (PA)…

Medical Physics · Physics 2018-08-15 Thomas Kirchner , Janek Gröhl , Lena Maier-Hein

High-throughput 3D quantitative phase imaging (QPI) in flow cytometry enables label-free, volumetric characterization of individual cells by reconstructing their refractive index (RI) distributions from multiple viewing angles during flow…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Enze Ye , Wei Lin , Shaochi Ren , Yakun Liu , Xiaoping Li , Hao Wang , He Sun , Feng Pan

We theoretically study the quantum Fisher information (QFI) of the SU(1,1) interferometer with phase shifts in two arms taking account of realistic noise effects. A generalized phase transform including the phase diffusion effect is…

Quantum Physics · Physics 2018-08-08 Xiu-Ling Hu , Dong Li , L. Q. Chen , Keye Zhang , Weiping Zhang , Chun-Hua Yuan

We present a novel approach for benchmarking and validating quantitative phase tomography (QPT) systems using three-dimensional microphantoms. These microphantoms, crafted from biological and imaging data, replicate the optical and…

Quantum illumination is a quantum-optical sensing technique in which an entangled source is exploited to improve the detection of a low-reflectivity object that is immersed in a bright thermal background. Here we describe and analyze a…

The correlation properties of light provide an outstanding tool to overcome the limitations of traditional imaging techniques. A relevant case is represented by correlation plenoptic imaging (CPI), a quantum-inspired volumetric imaging…

Entanglement is a key resource in quantum technologies, enhancing precision and resolution in imaging and sensing by leveraging the cross-correlation of photon pairs. This correlation enables precise time synchronization of photons reaching…

Detection of phase variations across optically transparent samples is often a difficult task. We propose and demonstrate a compact, lightweight and low cost quantitative phase contrast imager. Light diffracted from a pinhole is incident on…

We present an optical method to measure radio-frequency electro-optic phase modulation profiles by employing spectrum-to-time mapping realized by highly chirped optical pulses. We directly characterize temporal phase modulation profiles of…

Instrumentation and Detectors · Physics 2017-11-23 Michał Jachura , Jan Szczepanek , Wojciech Wasilewski , Michal Karpinski

In computational phase imaging with a microscope equipped with an array of light emitting diodes as illumination unit, conventional Fourier ptychographic microscopy achieves high resolution and wide-field reconstructions but is constrained…