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The treatment of malaria is a global health challenge that stands to benefit from the widespread introduction of a vaccine for the disease. A method has been developed to create a live organism vaccine using the sporozoites (SPZ) of the…
Mosquitoes are a major vector for malaria, causing hundreds of thousands of deaths in the developing world each year. Not only is the prevention of mosquito bites of paramount importance to the reduction of malaria transmission cases, but…
Malaria is a female anopheles mosquito-bite inflicted life-threatening disease which is considered endemic in many parts of the world. This article focuses on improving malaria detection from patches segmented from microscopic images of red…
Malaria is a serious global health problem which is especially devastating to the developing world. Mosquitoes are the carriers of the parasite responsible for the disease, and hence malaria control programs focus on controlling mosquito…
Malaria is considered one of the deadliest diseases in today world which causes thousands of deaths per year. The parasites responsible for malaria are scientifically known as Plasmodium which infects the red blood cells in human beings.…
Plasmodium vivax malaria is a mosquito-borne disease of significant public health importance. A defining feature of the within-host biology of P. vivax is the accrual of a hypnozoite reservoir, comprising a bank of quiescent parasites in…
Malaria is mosquito-borne blood disease caused by parasites of the genus Plasmodium. Conventional diagnostic tool for malaria is the examination of stained blood cell of patient in microscope. The blood to be tested is placed in a slide and…
Malaria is a serious disease caused by the Plasmodium parasite that transmitted through the bite of a female Anopheles mosquito and invades human erythrocytes. Malaria must be recognized precisely in order to treat the patient in time and…
A timely immunization can be effective against certain diseases and can save thousands of lives. However, for some diseases it has been difficult, so far, to develop an efficient vaccine. Malaria, a tropical disease caused by a parasite of…
Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by a reservoir of liver-stage parasites known as hypnozoites,…
Improving the efficiency of malaria diagnosis is one of the main goals of current malaria research. We have recently developed a magneto-optical (MO) method which allows high-sensitivity detection of malaria pigment (hemozoin) crystals via…
Malaria is an infectious disease with an immense global health burden. Plasmodium vivax is the most geographically widespread species of malaria. Relapsing infections, caused by the activation of liver-stage parasites known as hypnozoites,…
Malaria is a parasitic disease, transmitted by mosquito vectors. Plasmodium vivax presents particular challenges for disease control, in light of an undetectable reservoir of latent parasites (hypnozoites) within the host liver.…
Plasmodium (P.) falciparum and P. vivax are the two most common causes of malaria. While the majority of deaths and severe morbidity are due to P. falciparum, P. vivax poses a greater challenge to eliminating malaria outside of Africa due…
Malaria and other parasites, including virus often induce an increase in host lipids which the invaders use to their own advantage. We obtained encouraging results in our investigations on bird malaria with a new approach namely the use of…
In this paper, we suggested eleven protein targets to be used as possible vaccines against Plasmodium falciparum causative agent of almost two to three million deaths per year. A comprehensive analysis of protein target have been selected…
Malaria is transmitted to vertebrates via a mosquito bite, during which rod-like and crescent-shaped parasites, called sporozoites, are injected into the skin of the host. Searching for a blood capillary to penetrate, sporozoites move…
Plasmodium vivax is the most geographically widespread malaria parasite due to its ability to remain dormant (as a hypnozoite) in the human liver and subsequently reactivate. Given the majority of P. vivax infections are due to hypnozoite…
Wolbachia infection in Anopheles albimanus mosquitoes can render mosquitoes less capable of spreading malaria. We develop and analyze an ordinary differential equation model to evaluate the effectiveness of Wolbachia-based vector control…
Malaria is a serious infectious disease that is responsible for over half million deaths yearly worldwide. The major cause of these mortalities is late or inaccurate diagnosis. Manual microscopy is currently considered as the dominant…