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Metabolism and evolution are closely connected: if a mutation incurs extra energetic costs for an organism, there is a baseline selective disadvantage that may or may not be compensated for by other adaptive effects. A long-standing, but to…

Populations and Evolution · Quantitative Biology 2019-06-19 Efe Ilker , Michael Hinczewski

Population genetics struggles to model extinction; standard models track the relative rather than absolute fitness of genotypes, while the exceptions describe only the short-term transition from imminent doom to evolutionary rescue. But…

Populations and Evolution · Quantitative Biology 2017-02-20 Jason Bertram , Kevin Gomez , Joanna Masel

We demonstrate with a thought experiment that fitness-based population dynamical approaches to evolution are not able to make quantitative, falsifiable predictions about the long-term behavior of evolutionary systems. A key characteristic…

Populations and Evolution · Quantitative Biology 2015-05-14 Peter Klimek , Stefan Thurner , Rudolf Hanel

We seek models for the genotype evolution of agricultural animals, animals involved in primary production processes. Classical models for genotype evolution have tended to be very simple in order that analytic methods may be employed in…

Quantitative Methods · Quantitative Biology 2017-12-15 Vladimir Obolonkin , Anatoly Zherelo , George Krylov , Murray Jorgensen , Richard Spelman

A new model for evolving Evolutionary Algorithms (EAs) is proposed in this paper. The model is based on the Multi Expression Programming (MEP) technique. Each MEP chromosome encodes an evolutionary pattern that is repeatedly used for…

Neural and Evolutionary Computing · Computer Science 2021-10-13 Mihai Oltean

We propose a Markov chain approach for the evolution of a genealogical line of genomes. Our idealized genome has $N$ sites and each site can be in state $0$ or $1$. At each time step we pick a site at random. If the site is in state $0$ we…

Probability · Mathematics 2020-08-11 Rinaldo B. Schinazi

In this paper we analyze the equilibrium properties of a large class of stochastic processes describing the fundamental biological process within bacterial cells, {\em the production process of proteins}. Stochastic models classically used…

Molecular Networks · Quantitative Biology 2019-10-17 Philippe Robert

In this paper we study collective decision making on a multi-population, represented by a regular network of groups of individuals. Each group consists of a collection of players and every player can choose between two options. A group is…

Optimization and Control · Mathematics 2020-11-18 Wouter Baar , Dario Bauso

In this work we propose a physical model of organismal evolution, where phenotype, organism life expectancy, is directly related to genotype i.e. the stability of its proteins which can be determined exactly in the model. Simulating the…

Populations and Evolution · Quantitative Biology 2007-05-23 Konstantin B. Zeldovich , Boris E. Shakhnovich , Eugene I. Shakhnovich

We introduce a model of biological evolution where species evolve in response to biotic interactions and a fluctuating environmental stress. The species may either become extinct or mutate to acquire a new fitness value when the effective…

Statistical Mechanics · Physics 2012-12-19 Debarshee Bagchi , P. K. Mohanty

A model of genome evolution is proposed. Based on three assumptions the evolutionary theory of a genome is formulated. The general law on the direction of genome evolution is given. Both the deterministic classical equation and the…

Other Quantitative Biology · Quantitative Biology 2014-11-11 Liaofu Luo

We propose a variation of the GMS model of evolution of species. In this version, as in the GMS model, at each birth, the new species in the system is labeled with a random fitness mark, but in our variation, to each extinction event is…

Probability · Mathematics 2019-03-25 Carolina Grejo , Luiz Renato Fontes , Fábio Sternieri Marque

We considered a {multi-block} molecular model of biological evolution, in which fitness is a function of the mean types of alleles located at different parts (blocks) of the genome. We formulated an infinite population model with selection…

Populations and Evolution · Quantitative Biology 2015-06-12 David B. Saakian , Zara Kirakosyan , Chin-Kun Hu

The emergence of collective cooperation in competitive environments is a well-known phenomenon in biology, economics, and social systems. While most evolutionary game models focus on the evolution of strategies for a fixed game, how…

Physics and Society · Physics 2024-08-01 Onkar Sadekar , Andrea Civilini , Jesús Gómez-Gardeñes , Vito Latora , Federico Battiston

Segregation of populations is a key question in evolution theory. One important aspect is the relation between spatial organization and the population's composition. Here we study a specific example -- sectors in expanding bacterial…

Condensed Matter · Physics 2009-10-31 Ido Golding , Inon Cohen , Eshel Ben-Jacob

Coevolutionary dynamics is investigated in chemical catalysis, biological evolution, social and economic systems. The dynamics of these systems can be analyzed within the unifying framework of evolutionary game theory. In this Letter, we…

Populations and Evolution · Quantitative Biology 2012-06-12 Jens Christian Claussen , Arne Traulsen

Biological systems are typically highly open, non-equilibrium systems that are very challenging to understand from a statistical mechanics perspective. While statistical treatments of evolutionary biological systems have a long and rich…

Populations and Evolution · Quantitative Biology 2018-08-21 Hamid-Reza Rastegar-Sedehi , Chandrashekar Radhakrishnan , Samer Intissar Nehme , Liev Birman , Paula Velasquez , Tim Byrnes

Mutations in a microbial population can increase the frequency of a genotype not only by increasing its exponential growth rate, but also by decreasing its lag time or adjusting the yield (resource efficiency). The contribution of multiple…

Populations and Evolution · Quantitative Biology 2018-02-15 Michael Manhart , Bharat V. Adkar , Eugene I. Shakhnovich

We investigate the evolutionary dynamics of a population structured in phenotype, subjected to trait dependent selection with a linearly moving optimum and an asexual mode of reproduction. Our model consists of a non-local and non-linear…

Analysis of PDEs · Mathematics 2021-12-09 Raphaël Forien , Jimmy Garnier , Florian Patout

Naturally evolving proteins gradually accumulate mutations while continuing to fold to thermodynamically stable native structures. This process of neutral protein evolution is an important mode of genetic change, and forms the basis for the…

Populations and Evolution · Quantitative Biology 2007-05-23 Jesse D Bloom , Alpan Raval , Claus O Wilke