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Model selection and assessment with incomplete data pose challenges in addition to the ones encountered with complete data. There are two main reasons for this. First, many models describe characteristics of the complete data, in spite of…

Methodology · Statistics 2008-08-28 Geert Verbeke , Geert Molenberghs , Caroline Beunckens

Assessment of replicability is critical to ensure the quality and rigor of scientific research. In this paper, we discuss inference and modeling principles for replicability assessment. Targeting distinct application scenarios, we propose…

Methodology · Statistics 2021-05-11 Yi Zhao , Xiaoquan Wen

The advent of advanced AI underscores the urgent need for comprehensive safety evaluations, necessitating collaboration across communities (i.e., AI, software engineering, and governance). However, divergent practices and terminologies…

Software Engineering · Computer Science 2024-05-17 Boming Xia , Qinghua Lu , Liming Zhu , Zhenchang Xing

Evaluating the quality of a dialogue system is an understudied problem. The recent evolution of evaluation method motivated this survey, in which an explicit and comprehensive analysis of the existing methods is sought. We are first to…

Computation and Language · Computer Science 2021-08-04 Xinmeng Li , Wansen Wu , Long Qin , Quanjun Yin

Synthetic data has emerged as a powerful resource in life sciences, offering solutions for data scarcity, privacy protection and accessibility constraints. By creating artificial datasets that mirror the characteristics of real data, allows…

Background/Purpose: The use of artificial intelligence (AI) models for data-driven decision-making in different stages of employee lifecycle (EL) management is increasing. However, there is no comprehensive study that addresses…

We analyze different types of simulations that applied researchers can use to assess whether their inference methods reliably control false-positive rates. We show that different assessments involve trade-offs, varying in the types of…

Econometrics · Economics 2025-10-03 Bruno Ferman

Our binary intuitive understanding of life and lifelikeness is good enough for daily life, but not for research in the natural sciences. Here we propose an operational definition of lifeness of a particular entity as a scalar, product of…

Other Quantitative Biology · Quantitative Biology 2026-01-21 Mario Martinez-Saito

Modeling and simulation are recognized as important aspects of the scientific method for more than 70 years but its adoption in biology has been slow. Debates on its representativeness, usefulness, and whether the effort spent on such…

Quantitative Methods · Quantitative Biology 2023-02-21 Maurice HT Ling

Currently, software industries are using different SDLC (software development life cycle) models which are designed for specific purposes. The use of technology is booming in every perspective of life and the software behind the technology…

Software Engineering · Computer Science 2018-07-17 AZM Ehtesham Chowdhury , Abhijit Bhowmik , Hasibul Hasan , Md Shamsur Rahim

Life Cycle Assessment (LCA) is increasingly used to quantify and regulate the environmental impacts of Information and Communication Technology (ICT) systems. Since direct biosphere measurements are complicated to perform, we claim that the…

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

In molecular phylogeny, relationships among organisms are reconstructed using DNA or protein sequences and are displayed as trees. A linear increase in the number of sequences results in an exponential increase of possible trees. Thus,…

Genomics · Quantitative Biology 2007-05-23 Kerstin Hoef-Emden

Widespread population aging has made it critical to understand death rates at old ages. However, studying mortality at old ages is challenging because the data are sparse: numbers of survivors and deaths get smaller and smaller with age. We…

Applications · Statistics 2018-03-29 Dennis M. Feehan

In a recent empirical study we found that evaluating abstractions of Model-Driven Engineering (MDE) is not as straight forward as it might seem. In this paper, we report on the challenges that we as researchers faced when we conducted the…

Software Engineering · Computer Science 2012-09-27 Adrian Kuhn , Gail C. Murphy

Many statistical models have high accuracy on test benchmarks, but are not explainable, struggle in low-resource scenarios, cannot be reused for multiple tasks, and cannot easily integrate domain expertise. These factors limit their use,…

Computation and Language · Computer Science 2021-09-29 Andrew Lee , Jonathan K. Kummerfeld , Lawrence C. An , Rada Mihalcea

I present a critique of the methods used in a typical paper. This leads to three broad conclusions about the conventional use of statistical methods. First, results are often reported in an unnecessarily obscure manner. Second, the null…

Applications · Statistics 2013-03-05 Michael Wood

Network models are used to study interconnected systems across many physical, biological, and social disciplines. Such models often assume a particular network-generating mechanism, which when fit to data produces estimates of…

Social and Information Networks · Computer Science 2022-01-17 Ryan E. Langendorf , Matthew G. Burgess

Basic problems in complex systems are surveyed in connection with Life. As a key issue for complex systems, complementarity between syntax/rule/parts and semantics/behavior/whole is stressed. To address the issue, a constructive approach…

adap-org · Physics 2007-05-23 Kunihiko Kaneko

We compare two distinct approaches for querying data in the context of the life sciences. The first approach utilizes conventional databases to store the data and intuitive form-based interfaces to facilitate easy querying of the data.…

Information Retrieval · Computer Science 2012-10-03 Amir H. Asiaee , Prashant Doshi , Todd Minning , Satya Sahoo , Priti Parikh , Amit Sheth , Rick L. Tarleton
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