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New-generation space missions require satellites to carry substantial amounts of liquid propellant, making it essential to analyse the coupled control-structure-propellant dynamics in detail. While Computational Fluid Dynamics (CFD) offers…

Coronary Artery Disease (CAD) is one of the most common forms of heart disease, which is caused by a buildup of atherosclerotic plaque (known as stenosis) in the coronary arteries, leading to insufficient supplement of blood, oxygen, and…

Computational Engineering, Finance, and Science · Computer Science 2024-09-06 Haizhou Yang , C. Alberto Figueroa , Krishna Garikipati

Despite rapid improvements in the performance of central processing unit (CPU), the calculation cost of simulating chemically reacting flow using CFD remains infeasible in many cases. The application of the convolutional neural networks…

Machine Learning · Computer Science 2023-07-26 Joongoo Jeon , Juhyeong Lee , Sung Joong Kim

X-ray Computed Tomography (CT) is used to recover the true surfaces of fluid channels and fed to simulation tool (ANSYS) to create accurate cyber environment. The simulation tool also receives CT-assisted multiphase fluid profiles…

Fluid Dynamics · Physics 2024-08-06 Vaishali Sharma , Arpit Kumar , Snehlata Shakya , Mayank Goswami

Cerebral aneurysms are pathological dilations of intracranial arteries that can rupture with devastating consequences, including subarachnoid hemorrhage, stroke, and death. Accumulating evidence indicates that local hemodynamic forces play…

Other Quantitative Biology · Quantitative Biology 2025-05-22 Reza Bozorgpour , Pilwan Kim

We introduce a rapid and precise analytical approach for analyzing cerebral blood flow (CBF) using Diffuse Correlation Spectroscopy (DCS) with the application of the Extreme Learning Machine (ELM). Our evaluation of ELM and existing…

Machine Learning · Computer Science 2024-02-02 Xi Chen , Zhenya Zang , Xingda Li

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

Fluid Dynamics · Physics 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

Computational fluid dynamics (CFD) analysis is widely used in engineering. Although CFD calculations are accurate, the computational cost associated with complex systems makes it difficult to obtain empirical equations between system…

Fluid Dynamics · Physics 2022-04-08 Mehrad Ansari , Heta A. Gandhi , David G. Foster , Andrew D. White

Reliable prediction of turbulent flows is an important necessity across different fields of science and engineering. In Computational Fluid Dynamics (CFD) simulations, the most common type of models are eddy viscosity models that are…

Fluid Dynamics · Physics 2023-07-25 Minghan Chu , Weicheng Qian

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Objective: Lung cancer is a leading cause of cancer-related mortality worldwide, primarily due to delayed diagnosis and poor early detection. This study aims to develop a computer-aided diagnosis (CAD) system that leverages large…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Hafza Eman , Furqan Shaukat , Muhammad Hamza Zafar , Syed Muhammad Anwar

Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…

Medical Physics · Physics 2025-07-01 Oeshee Roy , Priyanshu Ghosh , Sayan Karmakar , Supratim Saha

Hemodynamics in the aorta from computational fluid dynamics (CFD) simulations can provide a comprehensive analysis of relevant cardiovascular diseases. Coupling the three-element Windkessel model with the patient-specific CFD simulation to…

Fluid Dynamics · Physics 2022-07-14 Zongze Li , Wenbin Mao

In this work we propose to validate the predictive capabilities of one-dimensional (1D) blood flow models with full three-dimensional (3D) models in the context of patient-specific coronary hemodynamics in hyperemic conditions. Such…

The analysis of quantitative hemodynamics and luminal pressure may add valuable information to aid treatment strategies and prognosis for aortic dissections. This work directly compared in vitro 4D-flow magnetic resonance imaging (MRI),…

Left ventricular ejection fraction (LVEF) assessment depends on echocardiography, limiting access in primary care and resource-constrained settings. We developed a multimodal machine-learning framework that combines engineered 12-lead ECG…

Machine Learning · Computer Science 2026-04-30 Catherine Ning , Yu Ma , Cindy Beini Wang , Sean McMahon , Joseph Radojevic , Steven Zweibel , Dimitris Bertsimas

The present focus of heart flow studies is largely based on flow within the left ventricle and how this flow changes when subject to disease. However, despite recent advancements, a simple tractable model of even healthy left ventricular…

Fluid Dynamics · Physics 2019-03-18 Giuseppe Di Labbio , Lyes Kadem

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on single physics, i.e. of the cardiac electrophysiology (EP),…

Numerical Analysis · Mathematics 2024-02-12 Elena Zappon , Matteo Salvador , Roberto Piersanti , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

A computational fluid dynamics (CFD) model is developed to simulate the dynamics of meniscus formation and capillary flow between vertical parallel plates. The arbitrary Lagrangian-Eulerian (ALE) approach was employed to predict and…

Fluid Dynamics · Physics 2020-03-12 Mohammad Naghashnejad , Hamidreza Shabgard
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