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Elucidating the biomechanical behavior of the myocardium is crucial for understanding cardiac physiology, but cannot be directly inferred from clinical imaging and typically requires finite element (FE) simulations. However, conventional FE…

Medical Physics · Physics 2025-06-27 Siyu Mu , Wei Xuan Chan , Choon Hwai Yap

Computational Fluid Dynamics (CFD) simulations are a very important tool for many industrial applications, such as aerodynamic optimization of engineering designs like cars shapes, airplanes parts etc. The output of such simulations, in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-12 Theodoros Georgiou , Sebastian Schmitt , Thomas Bäck , Nan Pu , Wei Chen , Michael Lew

Electromagnetic forming and perforations (EMFP) are complex and innovative high strain rate processes that involve electromagnetic-mechanical interactions for simultaneous metal forming and perforations. Instead of spending costly resources…

Numerical Analysis · Mathematics 2024-12-16 Avinash Chetry , Arup Nandy

Coronary artery disease, caused by the narrowing of coronary vessels due to atherosclerosis, is the leading cause of death worldwide. The diagnostic gold standard, fractional flow reserve (FFR), measures the trans-stenotic pressure ratio…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Guido Nannini , Julian Suk , Patryk Rygiel , Simone Saitta , Luca Mariani , Riccardo Maragna , Andrea Baggiano , Gianluca Pontone , Jelmer M. Wolterink , Alberto Redaelli

Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…

Source analysis of Electroencephalography (EEG) data requires the computation of the scalp potential induced by current sources in the brain. This so-called EEG forward problem is based on an accurate estimation of the volume conduction…

In this work the development of a machine learning-based Reduced Order Model (ROM) for the investigation of hemodynamics in a patient-specific configuration of Coronary Artery Bypass Graft (CABG) is proposed. The computational domain is…

Medical Physics · Physics 2023-08-08 Pierfrancesco Siena , Michele Girfoglio , Francesco Ballarin , Gianluigi Rozza

In this paper, our aim is to present (1) an embedded fracture model (EFM) for coupled flow and mechanics problem based on the dual continuum approach on the fine grid and (2) an upscaled model for the resulting fine grid equations. The…

Numerical Analysis · Mathematics 2018-11-14 Maria Vasilyeva , Eric T. Chung , Yalchin Efendiev , Jihoon Kim

This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Over several decades, electromechanical impedance (EMI) measurements have been employed as a basis for structural health monitoring and damage detection. Traditionally, Root-mean-squared-deviation (RMSD) and Cross-correlation (XCORR) based…

Applications · Statistics 2026-04-30 Sourabh Sangle , Sa'ed Alajlouni , Pablo A. Tarazaga

Interest in the application of engineering methods to problems in congenital heart disease has gained increased popularity over the past decade. The use of computational simulation to examine common clinical problems including single…

Medical Physics · Physics 2011-01-20 Irene Vignon Clementel , Alison L. Marsden , Jeffrey A. Feinstein

Computational fluid dynamics (CFD) simulation provides valuable information on blood flow from the vascular geometry. However, it requires extracting precise models of arteries from low-resolution medical images, which remains challenging.…

Computational Geometry · Computer Science 2023-06-14 Méghane Decroocq , Carole Frindel , Pierre Rougé , Makoto Ohta , Guillaume Lavoué

Computational Fluid Dynamics (CFD) is currently used to design and improve the hydraulic properties of biomedical devices, wherein the large scale blood circulation needs to be simulated by accounting for the mechanical response of red…

Fluid Dynamics · Physics 2024-12-24 F. Guglietta , M. Behr , L. Biferale , G. Falcucci , M. Sbragaglia

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

This study investigates the influence of aneurysm evolution on hemodynamic characteristics within the sac region. Using computational fluid dynamics (CFD), blood flow through the parent vessel and aneurysm sac was analyzed to assess the…

Quantitative Methods · Quantitative Biology 2026-02-17 Reza Bozorgpour , Jacob R. Rammer

Cardiovascular diseases are among the most important causes of global mortality. Computational Fluid Dynamics (CFD) is a powerful research tool that analyzes the hemodynamics of artery and blood flow patterns. In this study, CFD simulations…

Fluid Dynamics · Physics 2023-09-12 Osman Aycan , Adnan Topuz , Lyes Kadem

In fractured natural formations, the equations governing fluid flow and geomechanics are strongly coupled. Hydrodynamical properties depend on the mechanical configuration, and they are therefore difficult to accurately resolve using…

Numerical Analysis · Mathematics 2021-04-07 Matteo Cusini , Joshua A. White , Nicola Castelletto , Randolph R. Settgast

Heart failure remains a major public health challenge with growing costs. Ejection fraction (EF) is a key metric for the diagnosis and management of heart failure however estimation of EF using echocardiography remains expensive for the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-26 Walt Williams , Rohan Doshi , Yanran Li , Kexuan Liang
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