Related papers: Moonshots for aging
Due to increasing sensing capacity, smartphones offer unprecedented opportunity to monitor human health. Affect sensing is one such essential monitoring that can be achieved on smartphones. Information about affect can be useful for many…
The threat posed to humanity by global warming has led scientists to question the nature of their activities and the need to reduce the greenhouse gas emissions from research. Until now, most studies have aimed at quantifying the carbon…
Mortality is an instrument of natural selection. Evolutionary motivated theories imply its irreversibility and life history dependence. This is inconsistent with mortality data for protected populations. Accurate analysis yields mortality…
In recent we introduced, developed and established a new concept, model, methodology and principle for studying human longevity in terms of demographic basis. We call the new model the "Weon model", which is a general model modified from…
In order to understand the phenomenon of longevity in biological world, the relationship between the potential of longevity and the structural complexity of an organism is analyzed. I. The potential of longevity is the maximum lifespan of…
Well protected human and laboratory animal populations with abundant resources are evolutionary unprecedented, and their survival far beyond reproductive age may be a byproduct rather than tool of evolution. Physical approach, which takes…
Main objective of this study is to introduce an expert system-based mHealth application that takes Artificial Intelligence support by considering previously introduced solutions from the literature and employing possible requirements for a…
Application of some basic notions and statistics of ageing distributions used in mathematical theory of reliability including the Gini-type index is discussed as a methodological tool for investigation of human population ageing and…
It is now increasingly realized that the underlying mechanism which governs aging (ageing) is a complex interplay of genetic regulation and damage-accumulation. "Aging as a result of accumulation of 'faults' on cellular and molecular…
Because of lunar librations, the retroreflectors left on the moon do not, in general, face directly at the Earth. Usually this is regarded as a disadvantage. It results in a spread of arrival times, because each cube that comprises the…
Age dating starbursts is an exercise with many caveats. We attempt to summarise a discussion session that was lead along a rather optimistic guideline: the aim was to highlight that current age estimates, despite undeniable uncertainties,…
The most pragmatic first step in the all-but-inevitable 3rd-millennium V\"olkerwanderung of humanity throughout the Solar System is the establishment of a permanent human presence on the Moon. This research examines: 1. the human,…
Will the United Kingdom's ageing population be fit and independent, or suffer from greater chronic ill health? Healthy life expectancy is commonly used to assess this: it is an estimate of how many years are lived in good health over the…
The rise in chronic diseases over the last century presents a significant health and economic burden globally. Here we apply evolutionary medicine and life history theory to better understand their development. We highlight an imbalanced…
Improving the health of the nation's population and increasing the capabilities of the US healthcare system to support diagnosis, treatment, and prevention of disease is a critical national and societal priority. In the past decade,…
Although species longevity is subject to a diverse range of selective forces, the mortality curves of a wide variety of organisms are rather similar. We argue that aging and its universal characteristics may have evolved by means of a…
The chronological age used in demography describes the linear evolution of the life of a living being. The chronological age cannot give precise information about the exact developmental stage or aging processes an organism has reached. On…
There is a mounting crisis in delivering affordable healthcare in the US. For decades, key decision makers in the public and private sectors have considered cost-effectiveness in healthcare a top priority. Their actions have focused on…
Addressing the unavoidable bias inherent in supervised aging clocks, we introduce Sundial, a novel framework that models molecular dynamics through a diffusion field, capturing both the population-level aging process and the…
Cosmology seems extremely remote from everyday human practice and experience. It is usually taken for granted that cosmological data cannot rationally influence our beliefs about the fate of humanity -- and possible other intelligent…