Related papers: Moonshots for aging
Death has long been overlooked in evolutionary algorithms. Recent research has shown that death (when applied properly) can benefit the overall fitness of a population and can outperform sub-sections of a population that are "immortal" when…
A ball on a stick is a common and simple activity for teaching the phases of the Moon. This activity, like many others in physics and astronomy, gives students a perspective they otherwise could only imagine. For Moon phases, a third person…
The focus on managing problems that can arise for older adults has meant that extant HCI and Ageing research has not given the concepts of 'age' and 'ageing' the explicit theoretical attention they deserve. Attending to this gap, we…
The author proposes and investigates his old idea - a living human in space without the encumbrance of a complex space suit. Only in this condition can biological humanity seriously attempt to colonize space because all planets of Solar…
Solar system exploration provides numerous possibilities for advancing technosignature science. The search for life in the solar system includes missions designed to search for evidence of biosignatures on other planetary bodies, but many…
Advances in artificial intelligence (AI) will transform many aspects of our lives and society, bringing immense opportunities but also posing significant risks and challenges. The next several decades may well be a turning point for…
As cell proliferation is limited due to the loss of telomere repeats in DNA of normal somatic cells during division, telomere attrition can possibly play an important role in determining the maximum life span of organisms as well as…
Great apes, the other living members of our hominid family, become decrepit before the age of forty and rarely outlive their fertile years. In contrast, women - even in high mortality hunter-gatherer populations - usually remain healthy and…
Predicting an individual's aging trajectory is a central challenge in preventative medicine and bioinformatics. While machine learning models can predict chronological age from biomarkers, they often fail to capture the dynamic,…
In recent years, we have seen scientists attempt to model and explain human dynamics and, in particular, human movement. Many aspects of our complex life are affected by human movements such as disease spread and epidemics modeling, city…
Companion robots hold immense potential in providing emotional support to older adults in the rapidly aging world. However, questions have been raised regarding whether having a robotic companion benefits healthy older adults, how they…
The faint young Sun paradox remains an open question. Presented here is one possible solution to this apparent inconsistency, a more massive early Sun. Based on conditions on early Earth and Mars, a luminosity constraint is set as a…
The formation, composition and physical properties of lunar dust are incompletely characterised with regard to human health. While the physical and chemical determinants of dust toxicity for materials such as asbestos, quartz, volcanic…
Many complex systems experience damage accumulation which leads to aging, manifest as an increasing probability of system collapse with time. This naturally raises the question of how to maximize health and longevity in an aging system at…
Development of several alternative mathematical models for the biological system in question and discrimination between such models using experimental data is the best way to robust conclusions. Models which challenge existing theories are…
In this paper authors present a general methodology for age dependent reliability analysis of degrading or ageing systems, structures and components.The methodology is based on Bayesian methods and inference, its ability to incorporate…
The lunar surface allows a unique way forward in cosmology, to go beyond current limits. The far side provides an unexcelled radio-quiet environment for probing the dark ages via 21 cm interferometry to seek elusive clues on the nature of…
This roadmap outlines research pathways to determine whether Mars could be warmed with non-biological methods. It does not presuppose that warming Mars is desirable; its purpose is to identify what would need to be true for Mars to be…
Photosynthesis offers a convenient means of sustaining biospheres. We quantify the constraints for photosynthesis to be functional on the permanent nightside of tidally locked rocky exoplanets via reflected light from their exomoons. We…
Biological evolution continuously refines the design of species, resulting in highly optimised organisms over hundreds of millennia. Intuitively, we expect that random changes-evolution's primary mechanism-are more likely to be harmful than…