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We study the behavior of a Time-Aware Long Short-Term Memory Autoencoder, a state-of-the-art method, in the context of learning latent representations from irregularly sampled patient data. We identify a key issue in the way such recurrent…

Machine Learning · Computer Science 2019-02-12 Duc Thanh Anh Luong , Varun Chandola

Gradient descent computed by backpropagation (BP) is a widely used learning method for training artificial neural networks but has several limitations: it is computationally demanding, requires frequent manual tuning of the network…

Signal Processing · Electrical Eng. & Systems 2024-10-02 Jiaqi Xing , Libo Chen , ZeZheng Zhang , Mohammed Nazibul Hasan , Zhi-Bin Zhang

Transfer learning, which is to improve the learning performance in the target domain by leveraging useful knowledge from the source domain, often requires that those two domains are very close, which limits its application scope. Recently,…

Machine Learning · Computer Science 2020-06-16 Qiao Xiao , Yu Zhang

A prevailing trend in neural network research suggests that model performance improves with increasing depth and capacity - often at the cost of integrability and efficiency. In this paper, we propose a strategy to optimize small,…

Machine Learning · Computer Science 2025-08-14 Yanick Chistian Tchenko , Felix Mohr , Hicham Hadj Abdelkader , Hedi Tabia

Knowledge Distillation (KD) transfers knowledge from large models to small models and has recently achieved remarkable success. However, the reliability of existing KD methods in real-world applications, especially under distribution shift,…

Machine Learning · Computer Science 2025-07-22 Songming Zhang , Yuxiao Luo , Ziyu Lyu , Xiaofeng Chen

The growing use of artificial intelligence (AI) in education, particularly large language models (LLMs), has increased interest in intelligent tutoring systems. However, LLMs often show limited adaptivity and struggle to model learners'…

Since 2016, deep learning (DL) has advanced tomographic imaging with remarkable successes, especially in low-dose computed tomography (LDCT) imaging. Despite being driven by big data, the LDCT denoising and pure end-to-end reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Wenjun Xia , Hongming Shan , Ge Wang , Yi Zhang

Alzheimer's disease (AD) persists as a paramount challenge in neurological research, characterized by the pathological hallmarks of amyloid-$\beta$ (A$\beta$) plaques and neurofibrillary tangles composed of hyperphosphorylated tau. This…

Molecular Networks · Quantitative Biology 2025-12-05 She Xutong

Musculoskeletal disorders (MSDs) are a leading cause of disability worldwide, requiring advanced diagnostic and therapeutic tools for personalised assessment and treatment. Effective management of MSDs involves the interaction of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Martina Paccini , Simone Cammarasana , Giuseppe Patanè

Computational methods have complemented experimental and clinical neursciences and led to improvements in our understanding of the nervous systems in health and disease. In parallel, neuromodulation in form of electric and magnetic…

Neurons and Cognition · Quantitative Biology 2014-08-13 Markus A. Dahlem , Sebastian Rode , Arne May , Naoya Fujiwara , Yoshito Hirata , Kazuyuki Aihara , Jürgen Kurths

With the prevalence of Diabetes, the Diabetes Mellitus Retinopathy (DR) is becoming a major health problem across the world. The long-term medical complications arising due to DR have a significant impact on the patient as well as the…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Shreyas Rajesh Labhsetwar , Raj Sunil Salvi , Piyush Arvind Kolte , Veerasai Subramaniam venkatesh , Alistair Michael Baretto

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yiming Xu , Yixuan Liu , Yuhang Zhang , Ling Zheng , Yihan Wang , Qi Song

Artificial intelligence-enabled histopathological data analysis has become a valuable assistant to the pathologist. However, existing models lack representation and inference abilities compared with those of pathologists, especially in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-20 Bo Yu , Hechang Chen , Yunke Zhang , Lele Cong , Shuchao Pang , Hongren Zhou , Ziye Wang , Xianling Cong

Driven by the dual principles of smart education and artificial intelligence technology, the online education model has rapidly emerged as an important component of the education industry. Cognitive diagnostic technology can utilize…

Artificial Intelligence · Computer Science 2025-10-28 Zhifeng Wang , Meixin Su , Yang Yang , Chunyan Zeng , Lizhi Ye

This study introduces a novel approach for early Type 2 Diabetes Mellitus (T2DM) risk prediction using a tabular transformer (TabTrans) architecture to analyze longitudinal patient data. By processing patients` longitudinal health records…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Sulaiman Khan , Md. Rafiul Biswas , Zubair Shah

Alzheimer's disease (AD) is a progressive neurodegenerative condition necessitating early and precise diagnosis to provide prompt clinical management. Given the paramount importance of early diagnosis, recent studies have increasingly…

Machine Learning · Computer Science 2026-02-18 Fatemeh Khalvandi , Saadat Izadi , Abdolah Chalechale

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Hongming Li , Yong Fan

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

Research organisms provide invaluable insights into human biology and diseases, serving as essential tools for functional experiments, disease modeling, and drug testing. However, evolutionary divergence between humans and research…

Genomics · Quantitative Biology 2025-11-05 Hao Yuan , Christopher A. Mancuso , Kayla Johnson , Ingo Braasch , Arjun Krishnan

Spiking Neural Networks (SNNs) offer a promising alternative to traditional deep learning frameworks, since they provide higher computational efficiency due to event-driven information processing. SNNs distribute the analog values of pixel…

Machine Learning · Computer Science 2020-10-06 Isha Garg , Sayeed Shafayet Chowdhury , Kaushik Roy