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Related papers: Disease Knowledge Transfer across Neurodegenerativ…

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Intense debate in the Neurology community before 2010 culminated in hypothetical models of Alzheimer's disease progression: a pathophysiological cascade of biomarkers, each dynamic for only a segment of the full disease timeline. Inspired…

Neurons and Cognition · Quantitative Biology 2022-11-14 Neil P. Oxtoby

In Digital Pathology (DP), labeled data is generally very scarce due to the requirement that medical experts provide annotations. We address this issue by learning transferable features from weakly labeled data, which are collected from…

Computer Vision and Pattern Recognition · Computer Science 2020-01-23 Eu Wern Teh , Graham W. Taylor

Frontotemporal dementia and Alzheimer's disease are two common forms of dementia and are easily misdiagnosed as each other due to their similar pattern of clinical symptoms. Differentiating between the two dementia types is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Da Ma , Donghuan Lu , Karteek Popuri , Mirza Faisal Beg

Skin cancer, the most commonly found human malignancy, is primarily diagnosed visually via dermoscopic analysis, biopsy, and histopathological examination. However, unlike other types of cancer, automated image classification of skin…

Image and Video Processing · Electrical Eng. & Systems 2021-06-01 Yutong Li , Ruoqing Zhu , Annie Qu , Mike Yeh

Alzheimer's disease (AD) persists as a paramount challenge in neurological research, characterized by the pathological hallmarks of amyloid-beta (Abeta) plaques and neurofibrillary tangles composed of hyperphosphorylated tau. This review…

Neurons and Cognition · Quantitative Biology 2025-12-15 Xutong She

Parkinson's Disease (PD) is a neurodegenerative disease that currently does not have a cure. In order to facilitate disease management and reduce the speed of symptom progression, early diagnosis is essential. The current clinical,…

Image and Video Processing · Electrical Eng. & Systems 2019-09-11 Justin Quan , Lin Xu , Rene Xu , Tyrael Tong , Jean Su

In contrast to pedagogies like evidence-based teaching, personalized adaptive learning (PAL) distinguishes itself by closely monitoring the progress of individual students and tailoring the learning path to their unique knowledge and…

Computers and Society · Computer Science 2024-05-09 Ming Kuo , Shouvon Sarker , Lijun Qian , Yujian Fu , Xiangfang Li , Xishuang Dong

Progressive neurodegenerative diseases, including Alzheimer's disease (AD), multiple sclerosis (MS), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit complex, nonlinear trajectories that challenge deterministic…

Other Quantitative Biology · Quantitative Biology 2025-08-12 John D. Mayfield

Dementia is a devastating condition with profound implications for individuals, families, and healthcare systems. Early and accurate detection of dementia is critical for timely intervention and improved patient outcomes. While classical…

Quantum Physics · Physics 2025-07-18 Sounak Bhowmik , Talita Perciano , Himanshu Thapliyal

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

Applications · Statistics 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

The integration of digital twinning technologies is driving next-generation networks toward new capabilities, allowing operators to thoroughly understand network conditions, efficiently analyze valuable radio data, and innovate applications…

Networking and Internet Architecture · Computer Science 2025-09-03 Zifan Zhang , Minghong Fang , Mingzhe Chen , Yuchen Liu

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression toward earlier and better patient-specific pathology management. However, conventional approaches rarely take advantage of…

We study the problem of knowledge tracing (KT) where the goal is to trace the students' knowledge mastery over time so as to make predictions on their future performance. Owing to the good representation capacity of deep neural networks…

Computers and Society · Computer Science 2021-08-11 Xiaopeng Guo , Zhijie Huang , Jie Gao , Mingyu Shang , Maojing Shu , Jun Sun

Recent work on deep learning for tabular data demonstrates the strong performance of deep tabular models, often bridging the gap between gradient boosted decision trees and neural networks. Accuracy aside, a major advantage of neural models…

The detection of Alzheimer's disease (AD) from spontaneous speech has attracted increasing attention while the sparsity of training data remains an important issue. This paper handles the issue by knowledge transfer, specifically from both…

Computation and Language · Computer Science 2024-04-02 Ziyun Cui , Wen Wu , Wei-Qiang Zhang , Ji Wu , Chao Zhang

A lot of deep learning (DL) research these days is mainly focused on improving quantitative metrics regardless of other factors. In human-centered applications, like skin lesion classification in dermatology, DL-driven clinical decision…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Theodor Cheslerean-Boghiu , Melia-Evelina Fleischmann , Theresa Willem , Tobias Lasser

In many medical applications, interpretable models with high prediction performance are sought. Often, those models are required to handle semi-structured data like tabular and image data. We show how to apply deep transformation models…

The current methods for diagnosing Alzheimer Disease using Magnetic Resonance Imaging (MRI) have significant limitations. Many previous studies used 2D Transformers to analyze individual brain slices independently, potentially losing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Juan A. Castro-Silva , Maria N. Moreno Garcia , Diego H. Peluffo-Ordoñez

The scarcity of high-quality multimodal biomedical data limits the ability to effectively fine-tune pretrained Large Language Models (LLMs) for specialized biomedical tasks. To address this challenge, we introduce MINT (Multimodal…

Quantitative Methods · Quantitative Biology 2026-02-18 Zhanliang Wang , Da Wu , Quan Nguyen , Zhuoran Xu , Kai Wang

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li