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Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

Knowledge transfer plays a crucial role in cross-scene hyperspectral imaging (HSI). However, existing studies often overlook the challenges of gradient conflicts and dominant gradients that arise during the optimization of shared…

Image and Video Processing · Electrical Eng. & Systems 2025-12-11 Lu Huo , Haimin Zhang , Min Xu

Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

Quantitative Methods · Quantitative Biology 2020-08-04 Sanjukta Krishnagopal

Accurate diagnosis of Alzheimer's disease (AD) requires effectively integrating multimodal data and clinical expertise. However, existing methods often struggle to fully utilize multimodal information and lack structured mechanisms to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Qiuhui Chen , Jintao Wang , Gang Wang , Yi Hong

We propose a hybrid reconstruction framework for dual-spectral CT (DSCT) that integrates iterative methods with deep learning models. The reconstruction process consists of two complementary components: a knowledge-driven module and a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Ze Yuan , Wenbin Li , Shusen Zhao

Recent years have witnessed an increasing global population affected by neurodegenerative diseases (NDs), which traditionally require extensive healthcare resources and human effort for medical diagnosis and monitoring. As a crucial…

Machine Learning · Computer Science 2025-02-07 Haocong Rao , Minlin Zeng , Xuejiao Zhao , Chunyan Miao

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing…

Biological Physics · Physics 2015-05-14 Cesar A. Hidalgo , Nicholas Blumm , Albert-Laszlo Barabasi , Nicholas Christakis

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

Dementia of Alzheimer's Type (DAT) is a complex disorder influenced by numerous factors, but it is unclear how each factor contributes to disease progression. An in-depth examination of these factors may yield an accurate estimate of…

Facial Landmark Detection (FLD) in thermal imagery is critical for applications in challenging lighting conditions, but it is hampered by the lack of rich visual cues. Conventional cross-modal solutions, like feature fusion or image…

Machine Learning · Computer Science 2025-10-27 Qiyi Tong , Olivia Nocentini , Marta Lagomarsino , Kuanqi Cai , Marta Lorenzini , Arash Ajoudani

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…

Machine Learning · Statistics 2019-09-09 Bryan Lim , Mihaela van der Schaar

Diabetic retinopathy (DR) is a leading cause of vision loss among middle-aged and elderly people, which significantly impacts their daily lives and mental health. To improve the efficiency of clinical screening and enable the early…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Junlai Qiu , Yunzhu Chen , Hao Zheng , Yawen Huang , Yuexiang Li

Alzheimer diseases (ADs) involves cognitive decline and abnormal brain protein accumulation, necessitating timely diagnosis for effective treatment. Therefore, CAD systems leveraging deep learning advancements have demonstrated success in…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Saddam Hussain Khan

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline as its main symptom. In the research field of deep learning-assisted diagnosis of AD, traditional convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Yang Ming , Jiang Shi Zhong , Zhou Su Juan

Biomarker discovery in neurodegenerative diseases requires robust, interpretable frameworks capable of integrating high-dimensional multi-omics data under low-sample conditions. We propose a novel ensemble approach combining Graph Attention…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Byeonghee Lee , Joonsung Kang

Disease progression modeling (DPM) using longitudinal data is a challenging task in machine learning for healthcare that can provide clinicians with better tools for diagnosis and monitoring of disease. Existing DPM algorithms neglect…

Computer Vision and Pattern Recognition · Computer Science 2018-08-17 Mostafa Mehdipour Ghazi , Mads Nielsen , Akshay Pai , M. Jorge Cardoso , Marc Modat , Sebastien Ourselin , Lauge Sørensen

In the past few years, there are several researches on Parkinson's disease (PD) recognition using single-photon emission computed tomography (SPECT) images with deep learning (DL) approach. However, the DL model's complexity usually results…

Image and Video Processing · Electrical Eng. & Systems 2021-05-05 Theerasarn Pianpanit , Sermkiat Lolak , Phattarapong Sawangjai , Thapanun Sudhawiyangkul , Theerawit Wilaiprasitporn

Drug recommendation (DR) systems aim to support healthcare professionals in selecting appropriate medications based on patients' medical conditions. State-of-the-art approaches utilize deep learning techniques for improving DR, but fall…

Information Retrieval · Computer Science 2025-11-03 Yu Lin , Zhen Jia , Philipp Christmann , Xu Zhang , Shengdong Du , Tianrui Li

In this paper, we propose a novel deep learning method based on a new Hybrid ConvNet-Transformer architecture to detect and stage Parkinson's disease (PD) from gait data. We adopt a two-step approach by dividing the problem into two…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Safwen Naimi , Wassim Bouachir , Guillaume-Alexandre Bilodeau