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How to induce differentiated cells into pluripotent cells has elicited researchers' interests for a long time since pluripotent stem cells are able to offer remarkable potential in numerous subfields of biological research. However, the…

Molecular Networks · Quantitative Biology 2014-12-09 Jiawei Yan , Pu Zheng , Xingjie Pan

We construct a model of cell reprogramming (the conversion of fully differentiated cells to a state of pluripotency, known as induced pluripotent stem cells, or iPSCs) which builds on key elements of cell biology viz. cell cycles and cell…

Cell Behavior · Quantitative Biology 2017-09-25 R Hannam , A Annibale , R Kuehn

This paper presents advancements in automated early-stage prediction of the success of reprogramming human induced pluripotent stem cells (iPSCs) as a potential source for regenerative cell therapies.The minuscule success rate of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Abhineet Singh , Ila Jasra , Omar Mouhammed , Nidheesh Dadheech , Nilanjan Ray , James Shapiro

When a program is loaded into memory for execution, the relative position of its basic blocks is crucial, since loading basic blocks that are unlikely to be executed first places them high in the instruction-memory hierarchy only to be…

Operating Systems · Computer Science 2007-05-23 C. A. G. Assis , E. S. T. Fernandes , V. C. Barbosa

This paper presents an iterative training of neural networks for intra prediction in a block-based image and video codec. First, the neural networks are trained on blocks arising from the codec partitioning of images, each paired with its…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Thierry Dumas , Franck Galpin , Philippe Bordes

We consider distributed computations between two parties carried out over a noisy channel that may erase messages. Following a noise model proposed by Dani et al. (2018), the noise level observed by the parties during the computation in our…

Data Structures and Algorithms · Computer Science 2019-09-17 Ran Gelles , Siddharth Iyer

Departing from traditional communication theory where decoding algorithms are assumed to perform without error, a system where noise perturbs both computational devices and communication channels is considered here. This paper studies…

Information Theory · Computer Science 2010-05-31 Lav R. Varshney

\emph{Resistive memories}, such as \emph{phase change memories} and \emph{resistive random access memories} have attracted significant attention in recent years due to their better scalability, speed, rewritability, and yet non-volatility.…

Information Theory · Computer Science 2021-09-22 Yeow Meng Chee , Michal Horovitz , Alexander Vardy , Van Khu Vu , Eitan Yaakobi

Discrete structures are currently second-class in differentiable programming. Since functions over discrete structures lack overt derivatives, differentiable programs do not differentiate through them and limit where they can be used. For…

Programming Languages · Computer Science 2025-11-20 Joey Velez-Ginorio , Nada Amin , Konrad Kording , Steve Zdancewic

Recent developments in synthetic biology, next-generation sequencing, and machine learning provide an unprecedented opportunity to rationally design new disease treatments based on measured responses to gene perturbations and drugs to…

Molecular Networks · Quantitative Biology 2024-03-12 Thomas P. Wytock , Adilson E. Motter

The asymptotic iterative decoding performances of low-density parity-check (LDPC) codes using min-sum (MS) and sum-product (SP) decoding algorithms on memoryless binary-input output-symmetric (MBIOS) channels are analyzed in this paper. For…

Information Theory · Computer Science 2007-07-13 Chun-Hao Hsu , Achilleas Anastasopoulos

In cellular reprogramming, almost all epigenetic memories of differentiated cells are erased by the overexpression of few genes, regaining pluripotency, potentiality for differentiation. Considering the interplay between oscillatory gene…

Biological Physics · Physics 2021-09-14 Yuuki Matsushita , Tetsuhiro S. Hatakeyama , Kunihiko Kaneko

Predictive coding networks are neuroscience-inspired models with roots in both Bayesian statistics and neuroscience. Training such models, however, is quite inefficient and unstable. In this work, we show how by simply changing the temporal…

Neural and Evolutionary Computing · Computer Science 2024-02-08 Tommaso Salvatori , Yuhang Song , Yordan Yordanov , Beren Millidge , Zhenghua Xu , Lei Sha , Cornelius Emde , Rafal Bogacz , Thomas Lukasiewicz

Traditional source separation approaches train deep neural network models end-to-end with all the data available at once by minimizing the empirical risk on the whole training set. On the inference side, after training the model, the user…

Replay in neural networks involves training on sequential data with memorized samples, which counteracts forgetting of previous behavior caused by non-stationarity. We present a method where these auxiliary samples are generated on the fly,…

Machine Learning · Computer Science 2020-12-15 Xu Ji , Joao Henriques , Tinne Tuytelaars , Andrea Vedaldi

Genetic Programming is an evolutionary algorithm that generates computer programs, or mathematical expressions, to solve complex problems. In this Guide, we demonstrate how to use Genetic Programming to develop surrogate models to mitigate…

Near term quantum computers suffer from the presence of different noise sources. In order to mitigate for this effect and acquire results with significantly better accuracy, there is the urge of designing efficient error correction or error…

We consider the problem of neural association for a network of non-binary neurons. Here, the task is to first memorize a set of patterns using a network of neurons whose states assume values from a finite number of integer levels. Later,…

Neural and Evolutionary Computing · Computer Science 2013-02-18 Amir Hesam Salavati , K. Raj Kumar , Amin Shokrollahi

We introduce a convergent iterative algorithm for finding the optimal coding and decoding operations for an arbitrary noisy quantum channel. This algorithm does not require any error syndrome to be corrected completely, and hence also finds…

Quantum Physics · Physics 2007-07-26 M. Reimpell , R. F. Werner

We consider a parallel computational model that consists of $P$ processors, each with a fast local ephemeral memory of limited size, and sharing a large persistent memory. The model allows for each processor to fault with bounded…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-15 Guy E. Blelloch , Phillip B. Gibbons , Yan Gu , Charles McGuffey , Julian Shun
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