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Biomaterial systems have allowed for the in vitro production of complex, emergent tissue behaviors that were not possible with conventional 2D culture systems allowing for analysis of the normal development as well as disease processes. We…

Tissues and Organs · Quantitative Biology 2019-10-16 Matthew S Hall , Joseph T Decker , Lonnie D Shea

Memories are stored, retained, and recollected through complex, coupled processes operating on multiple timescales. To understand the computational principles behind these intricate networks of interactions we construct a broad class of…

Neurons and Cognition · Quantitative Biology 2015-07-29 Marcus K. Benna , Stefano Fusi

Thanks to recent technological advances, it is now possible to track with an unprecedented precision and for long periods of time the movement patterns of many living organisms in their habitat. The increasing amount of data available on…

Populations and Evolution · Quantitative Biology 2015-05-19 Denis Boyer , Peter D. Walsh

By dynamic planning, we refer to the ability of the human brain to infer and impose motor trajectories related to cognitive decisions. A recent paradigm, active inference, brings fundamental insights into the adaptation of biological…

Artificial Intelligence · Computer Science 2024-11-13 Matteo Priorelli , Ivilin Peev Stoianov

Associative learning is one of the key mechanisms displayed by living organisms in order to adapt to their changing environments. It was early recognized to be a general trait of complex multicellular organisms but also found in "simpler"…

Cell Behavior · Quantitative Biology 2017-01-24 Javier Macia , Blai Vidiella , Ricard Sole

Process mining provides methods to analyse event logs generated by information systems during the execution of processes. It thereby supports the design, validation, and execution of processes in domains ranging from healthcare, through…

Databases · Computer Science 2024-02-06 Mehdi Acheli , Daniela Grigori , Matthias Weidlich

We have found the optimal condition of the work performed by the quantum Szilard engine (SZE) containing multi-particles. Usually the optimal work of a cyclic engine is achieved when the whole thermodynamic process is reversible. Although…

Quantum Physics · Physics 2014-01-09 Hee Joon Jeon , Sang Wook Kim

An explanatory model for the emergence of evolvable units must display emerging structures that (1) preserve themselves in time (2) self-reproduce and (3) tolerate a certain amount of variation when reproducing. To tackle this challenge,…

Adaptation and Self-Organizing Systems · Physics 2020-06-22 Germán Kruszewski , Tomas Mikolov

To better understand the structure and function of complex systems, researchers often represent direct interactions between components in complex systems with networks, assuming that indirect influence between distant components can be…

Physics and Society · Physics 2018-06-18 Renaud Lambiotte , Martin Rosvall , Ingo Scholtes

Several abilities of biological systems, such as adaptation to natural environment, or of animals to learn patterns when appropriately trained, are features that are extremely useful, if emulated by electronic circuits, in applications…

Neurons and Cognition · Quantitative Biology 2011-12-22 M. Di Ventra , Y. V. Pershin

To determine an optimal plan for complex tasks, one often deals with dynamic and hierarchical relationships between several entities. Traditionally, such problems are tackled with optimal control, which relies on the optimization of cost…

Robotics · Computer Science 2025-05-12 Matteo Priorelli , Ivilin Peev Stoianov

Quantifying the flow of energy within and through fluctuating nanoscale systems poses a significant challenge to understanding microscopic biological machines. A common approach involves coarse-graining, which allows a simplified…

Statistical Mechanics · Physics 2021-03-12 Steven J Large , David A Sivak

This paper addresses the lower limits of encoding and processing the information acquired through interactions between an internal system (robot algorithms or software) and an external system (robot body and its environment) in terms of…

Robotics · Computer Science 2023-08-21 Basak Sakcak , Kalle G. Timperi , Vadim Weinstein , Steven M. LaValle

Generative models offer a direct way of modeling complex data. Energy-based models attempt to encode the statistical correlations observed in the data at the level of the Boltzmann weight associated with an energy function in the form of a…

Disordered Systems and Neural Networks · Physics 2024-04-10 Aurélien Decelle , Cyril Furtlehner , Alfonso De Jesus Navas Gómez , Beatriz Seoane

Molecular dynamics (MD) has become a powerful tool for studying biophysical systems, due to increasing computational power and availability of software. Although MD has made many contributions to better understanding these complex…

Computational Physics · Physics 2019-09-27 Yihang Wang , Joao Marcelo Lamim Ribeiro , Pratyush Tiwary

Speculative techniques in microarchitectures relax various dependencies in programs, which contributes to the complexity of (weak) memory models. We show using WMM, a new weak memory model, that the model becomes simpler if it includes…

Programming Languages · Computer Science 2016-06-20 Sizhuo Zhang , Arvind , Muralidaran Vijayaraghavan

Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant advances have been made in this area for…

Methodology · Statistics 2025-03-14 Matteo D'Alessandro , Magne Thoresen

Free energy landscapes encode the kinetics, intermediates, and transition states that govern molecular processes and are thus a key target of single biomolecule research. Typical approaches to deriving optimal, error-minimizing,…

Biological Physics · Physics 2025-11-25 Oliver Cheng , Zosia Adamska , Michael P. Brenner , Megan C. Engel

In complex environments, there are costs to both ignorance and perception. An organism needs to track fitness-relevant information about its world, but the more information it tracks, the more resources it must devote to memory and…

Neurons and Cognition · Quantitative Biology 2018-10-17 Sarah E. Marzen , Simon DeDeo

The problem of interpretability of machine learning architecture in particle physics has no agreed-upon definition, much less any proposed solution. We present a first modest step toward these goals by proposing a definition and…

High Energy Physics - Phenomenology · Physics 2025-03-11 Andrew J. Larkoski
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