Related papers: Biochemical Szilard engines for memory-limited inf…
Building mathematical models of brains is difficult because of the sheer complexity of the problem. One potential starting point is through basal cognition, which gives abstract representation of a range of organisms without central nervous…
Feedback can be utilized to convert information into useful work, making it an effective tool for increasing the performance of thermodynamic engines. Using feedback reversibility as a guiding principle, we devise a method for designing…
Can a micron sized sack of interacting molecules understand, and adapt to a constantly-fluctuating environment? Cellular life provides an existence proof in the affirmative, but the principles that allow for life's existence are far from…
The importance of low power consumption is widely acknowledged due to the increasing use of portable devices, which require minimizing the consumption of energy. The energy in a computational system depends heavily on the software being…
Life relies on a sophisticated metabolic molecular machinery that turns over high-energy molecules to evolve complex macromolecules and assemblies. At the molecular origin of life, such machinery was absent, implying the need for simple yet…
Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can cells be optimally efficient, and if not, why? We show that,…
Despite the obvious advantage of simple life forms capable of fast replication, different levels of cognitive complexity have been achieved by living systems in terms of their potential to cope with environmental uncertainty. Against the…
We study experimentally work fluctuations in a Szilard engine that extracts work from information encoded as the occupancy of an electron level in a semiconductor quantum dot. We show that as the average work extracted per bit of…
Modeling biological processes is a highly demanding task because not all processes are fully understood. Mathematical models allow us to test hypotheses about possible mechanisms of biological processes. The mathematical mechanisms…
Exascale computing holds great opportunities for molecular dynamics (MD) simulations. However, to take full advantage of the new possibilities, we must learn how to focus computational power on the discovery of complex molecular mechanisms,…
Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can cells be optimally efficient, and if not, why? We show that,…
In thermodynamics, an agent's ability to extract work is fundamentally constrained by their environment. Traditional frameworks struggle to capture how strategic decision-making under uncertainty, particularly an agent's tolerance for risk,…
The problem of statistical inference in its various forms has been the subject of decades-long extensive research. Most of the effort has been focused on characterizing the behavior as a function of the number of available samples, with far…
Many statistical models have high accuracy on test benchmarks, but are not explainable, struggle in low-resource scenarios, cannot be reused for multiple tasks, and cannot easily integrate domain expertise. These factors limit their use,…
Embedded systems become more and more widespread, especially autonomous ones, and clearly tend to be ubiquitous. In such systems, low-power and low-energy usage get ever more crucial. Furthermore, these issues also become paramount in…
A central challenge in climate science and applied mathematics is developing data-driven models of multiscale systems that capture both stationary statistics and responses to external perturbations. Current neural climate emulators aim to…
The field of artificial intelligence faces significant challenges in achieving both biological plausibility and computational efficiency, particularly in visual learning tasks. Current artificial neural networks, such as convolutional…
Thermodynamics establishes that information acquired through measurement can be converted into work, as exemplified by Maxwell's demon and Szilard engines. Most experimental realizations of information engines, however, implicitly assume…
Combining a spatiotemporal, multi-agent based model of a foraging ecosystem with linear, genetically programmed rules for the agents' behaviors results in implicit, endogenous, objective functions and selection algorithms based on "natural…
Complex systems are fascinating because their rich macroscopic properties emerge from the interaction of many simple parts. Understanding the building principles of these emergent phenomena in nature requires assessing natural complex…