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Efficient operation of intelligent machines in the real world requires methods that allow them to understand and predict the uncertainties presented by the unstructured environments with good accuracy, scalability and generalization,…

Optimization strategies driven by machine learning, such as Bayesian optimization, are being explored across experimental sciences as an efficient alternative to traditional design of experiment. When combined with automated laboratory…

Optimization and Control · Mathematics 2022-10-18 Riley J. Hickman , Matteo Aldeghi , Florian Häse , Alán Aspuru-Guzik

The applicability of computational models to the biological world is an active topic of debate. We argue that a useful path forward results from abandoning hard boundaries between categories and adopting an observer-dependent, pragmatic…

Multiagent Systems · Computer Science 2022-12-22 Joshua Bongard , Michael Levin

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

Within the field of automated driving, a clear trend in environment perception tends towards more sensors, higher redundancy, and overall increase in computational power. This is mainly driven by the paradigm to perceive the entire…

Robotics · Computer Science 2023-01-27 Matti Henning , Johannes Müller , Fabian Gies , Michael Buchholz , Klaus Dietmayer

Efficiently harvesting thermodynamic resources requires a precise understanding of their structure. This becomes explicit through the lens of information engines -- thermodynamic engines that use information as fuel. Maximizing the work…

Statistical Mechanics · Physics 2024-02-28 Alexander B. Boyd , James P. Crutchfield , Mile Gu , Felix C. Binder

Many proposed applications of neural networks in machine learning, cognitive/brain science, and society hinge on the feasibility of inner interpretability via circuit discovery. This calls for empirical and theoretical explorations of…

Artificial Intelligence · Computer Science 2025-04-02 Federico Adolfi , Martina G. Vilas , Todd Wareham

Nowadays new technologies, and especially artificial intelligence, are more and more established in our society. Big data analysis and machine learning, two sub-fields of artificial intelligence, are at the core of many recent breakthroughs…

Machine Learning · Statistics 2021-06-22 Antonio Sutera

Biochars have been attracting renewed attention as economical and environmentally friendly carbon sequestration materials with a diverse range of applications. However, experimental developments may be limited by the lack of molecular-level…

Materials Science · Physics 2024-06-11 Rosie Wood , Ondrej Masek , Valentina Erastova

This thesis develops signal-processing algorithms and implementation schemes under constraints of minimal parallelism and memory space, with the goal of improving energy efficiency of low-power computing hardware. We propose (i) a…

Signal Processing · Electrical Eng. & Systems 2025-12-30 Sergey Salishev

Finding the model that best describes a high-dimensional dataset is a daunting task, even more so if one aims to consider all possible high-order patterns of the data, going beyond pairwise models. For binary data, we show that this task…

Artificial Intelligence · Computer Science 2024-08-28 Clélia de Mulatier , Matteo Marsili

In this thesis I explore challenging discrete energy minimization problems that arise mainly in the context of computer vision tasks. This work motivates the use of such "hard-to-optimize" non-submodular functionals, and proposes methods…

Computer Vision and Pattern Recognition · Computer Science 2012-11-09 Shai Bagon

Cognitive maps play a crucial role in facilitating flexible behaviour by representing spatial and conceptual relationships within an environment. The ability to learn and infer the underlying structure of the environment is crucial for…

Artificial Intelligence · Computer Science 2023-06-26 Daria de Tinguy , Toon Van de Maele , Tim Verbelen , Bart Dhoedt

Biological systems sense and extract information from fluctuating signals while operating under energetic constraints and limited resolution. We introduce a general chemical model in which a sensor, coupled to a signaling pathway activated…

Statistical Mechanics · Physics 2025-12-09 Giorgio Nicoletti , Ivan Di Terlizzi , Daniel Maria Busiello

Many living and artificial systems improve their fitness or performance by adapting to changing environments or diverse training data. However, it remains unclear how such environmental variation influences adaptation, what is learned in…

Computational Physics · Physics 2026-04-09 Mengjie Zu , Carl P. Goodrich

We investigate the efficiency of systems of molecular motors operating at maximum power. We consider two models of kinesin motors on a microtubule: for both the simplified and the detailed model, we find that the many-body exclusion effect…

Statistical Mechanics · Physics 2015-06-11 N. Golubeva , A. Imparato

Living things avoid equilibrium using molecular machines. Such microscopic soft-matter objects encounter relatively large friction and fluctuations. We discuss design principles for effective molecular machine operation in this unfamiliar…

Statistical Mechanics · Physics 2017-12-18 Aidan I Brown , David A Sivak

We study a quantum Szilard engine that is not powered by heat drawn from a thermal reservoir, but rather by projective measurements. The engine is constituted of a system $\mathcal{S}$, a weight $\mathcal{W}$, and a Maxwell demon…

Quantum Physics · Physics 2017-11-17 M. Hamed Mohammady , Janet Anders

Machine-Learning Interatomic Potentials (MLIPs) have surged in popularity due to their promise of expanding the spatiotemporal scales possible for simulating molecules with high fidelity. The accuracy of any MLIP is dependent on the data…

Soft Condensed Matter · Physics 2026-02-27 Natalie E. Hooven , Arthur Y. Lin , Charles H. Carroll , Rose K. Cersonsky

In collective robotic systems, the automatic generation of controllers for complex tasks is still a challenging problem. Open-ended evolution of complex robot behaviors can be a possible solution whereby an intrinsic driver for pattern…

Neural and Evolutionary Computing · Computer Science 2019-10-14 Tanja Katharina Kaiser , Heiko Hamann