Related papers: Output-Oblivious Stochastic Chemical Reaction Netw…
Many biological systems can be modeled as a chemical reaction network with unknown parameters. Data available to identify these parameters are often in the form of a stationary distribution, such as that obtained from measurements of a cell…
Chemical reaction networks (CRNs) are a standard formalism used in chemistry and biology to reason about the dynamics of molecular interaction networks. In their interpretation by ordinary differential equations, CRNs provide a…
Due to the limitations of Moore's Law and the increasing demand of computing, optical neural network (ONNs) are gradually coming to the stage as an alternative to electrical neural networks. The control of nonlinear activation functions in…
Stochastic reaction networks are dynamical models of biochemical reaction systems and form a particular class of continuous-time Markov chains on $\mathbb{N}^n$. Here we provide a fundamental characterisation that connects structural…
We propose a fully autonomous, thermodynamically consistent set of chemical reactions that implements a spiking neuron. This chemical neuron is able to learn input patterns in a Hebbian fashion. The system is scalable to arbitrarily many…
In this work, we design a type of controller that consists of adding a specific set of reactions to an existing mass-action chemical reaction network in order to control a target species. This set of reactions is effective for both…
The coefficient sequences of multivariate rational functions appear in many areas of combinatorics. Their diagonal coefficient sequences enjoy nice arithmetic and asymptotic properties, and the field of analytic combinatorics in several…
Neural networks achieve outstanding accuracy in classification and regression tasks. However, understanding their behavior still remains an open challenge that requires questions to be addressed on the robustness, explainability and…
This paper analyses of a stochastic model of a chemical reaction network with three types of chemical species ${\cal R}$, ${\cal M}$ and ${\cal U}$ that interact to transform a flow of external resources, the chemical species ${\cal Q}$, to…
Reaction networks have become a major modelling framework in the biological sciences from epidemiology and population biology to genetics and cellular biology. In recent years, much progress has been made on stochastic reaction networks…
Networks are fundamental building blocks for representing data, and computations. Remarkable progress in learning in structurally defined (shallow or deep) networks has recently been achieved. Here we introduce evolutionary exploratory…
The question of what kind of convolutional neural network (CNN) structure performs well is fascinating. In this work, we move toward the answer with one more step by connecting zero stability and model performance. Specifically, we found…
If $(X^N)_{N=1,2,...}$ is a sequence of Markov processes which solve the martingale problems for some operators $(G^N)_{N=1,2,...}$, it is a classical task to derive a limit result as $N\to\infty$, in particular a weak process limit with…
Experiments with networks of discrete reactive bistable electrochemical elements organized in regular and nonregular tree networks are presented to confirm an alternative to the Turing mechanism for the formation of self-organized…
This paper is concerned with the utilization of deterministically modeled chemical reaction networks for the implementation of (feed-forward) neural networks. We develop a general mathematical framework and prove that the ordinary…
Elicitable functionals and (strictly) consistent scoring functions are of interest due to their utility of determining (uniquely) optimal forecasts, and thus the ability to effectively backtest predictions. However, in practice, assuming…
We present two quantitative behavioral equivalences over species of a chemical reaction network (CRN) with semantics based on ordinary differential equations. Forward CRN bisimulation identifies a partition where each equivalence class…
A chemical reaction mechanism (CRM) is a sequence of molecular-level events involving bond-breaking/forming processes, generating transient intermediates along the reaction pathway as reactants transform into products. Understanding such…
Insufficient capability of existing subspace clustering methods to handle data coming from nonlinear manifolds, data corruptions, and out-of-sample data hinders their applicability to address real-world clustering and classification…
Control barrier functions (CBFs) have been demonstrated as an effective method for safety-critical control of autonomous systems. Although CBFs are simple to deploy, their design remains challenging, motivating the development of…