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This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

Purpose: Respiratory motion and the interplay effect cause the dose delivered to a patient with spot-scanned proton therapy to differ from the dose planned for during optimization. A new 4D robust optimization methodology was developed…

Purpose: We present a framework for robust automated treatment planning using machine learning, comprising scenario-specific dose prediction and robust dose mimicking. Methods: The scenario dose prediction pipeline is divided into the…

Medical Physics · Physics 2022-10-12 Oskar Eriksson , Tianfang Zhang

Computer-Assisted Interventions enable clinicians to perform precise, minimally invasive procedures, often relying on advanced imaging methods. Cone-beam computed tomography (CBCT) can be used to facilitate computer-assisted interventions,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-04 Maximilian E. Tschuchnig , Philipp Steininger , Michael Gadermayr

We recently built an analytical source model for GPU-based MC dose engine. In this paper, we present a sampling strategy to efficiently utilize this source model in GPU-based dose calculation. Our source model was based on a concept of…

Medical Physics · Physics 2015-03-06 Zhen Tian , Michael Folkerts , Yongbao Li , Feng Shi , Steve B. Jiang , Xun Jia

We analyze and compare the computational complexity of different simulation strategies for Monte Carlo in the setting of classically scaled population processes. This allows a range of widely used competing strategies to be judged…

Numerical Analysis · Mathematics 2018-06-05 David F. Anderson , Desmond J. Higham , Yu Sun

Dose painting has been developed to modulate the required dose in the target area without increasing the toxicity in healthy areas. Apart from determining the accurate location and size of tumors, quantitative functional imaging can be used…

Medical Physics · Physics 2020-11-24 Yaru Pang , Gary Royle , Spyros Manolopoulos

Repeated computed tomography (CT) scans are required in some clinical applications such as image-guided radiotherapy and follow-up observations over a time period. To optimize the radiation dose utility, a normal-dose (or full-dose) CT scan…

Medical Physics · Physics 2017-02-23 Hao Zhang , Jianhua Ma , William Moore , Zhengrong Liang

Scatter due to interaction of photons with the imaged object is a fundamental problem in X-ray Computed Tomography (CT). It manifests as various artifacts in the reconstruction, making its abatement or correction critical for image quality.…

Medical Physics · Physics 2024-01-30 Berk Iskender , Yoram Bresler

With the mushrooming use of computed tomography (CT) images in clinical decision making, management of CT data becomes increasingly difficult. From the patient identification perspective, using the standard DICOM tag to track patient…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Jiuwen Zhu , Hu Han , S. Kevin Zhou

Computerized Tomography assembly and system configuration are optimized for enhanced invertibility in sparse data reconstruction. Assembly generating maximum principal components/condition number of weight matrix is designated as best…

Instrumentation and Detectors · Physics 2023-10-02 Mayank Goswami

The paper discusses some 3D simulations to compute the ionizing radiation dose during laser-plasma experiments leading to the generation of accelerated protons and electrons. Also, we suggest a new method to increase the measurement…

Instrumentation and Detectors · Physics 2019-10-02 M. Ganciu , A. Chirosca , A. Groza , E. Stancu , O. Stoican , D. B. Dreghici , B. Butoi , C. Ticos , B. Mihalcea , B. Cramariuc

Objectives: This study aims to characterize the dose-performance relationship for opportunistic CT and disentangle the contributions of segmentation failure and dose-dependent HU bias to performance degradation. Methods: Simulated low-dose…

The advent of computed tomography significantly improves patient health regarding diagnosis, prognosis, and treatment planning and verification. However, tomographic imaging escalates concomitant radiation doses to patients, inducing…

Monte Carlo simulations are increasingly used in scintigraphic imaging to model imaging systems and to develop and assess tomographic reconstruction algorithms and correction methods for improved image quantitation. GATE (GEANT 4…

Instrumentation and Detectors · Physics 2009-11-10 D. Lazaro , I. Buvat , G. Loudos , D. Strul , G. Santin , N. Giokaris , D. Donnarieix , L. Maigne , V. Spanoudaki , S. Styliaris , S. Staelens , V. Breton

In many applications, such as plasma edge simulation of a nuclear fusion reactor, a coupled PDE/kinetic description is required, which is usually solved with a coupled finite-volume/Monte-Carlo method. Different procedures have been…

Numerical Analysis · Mathematics 2020-12-17 Bert Mortier , Martine Baelmans , Giovanni Samaey

Purpose: Very fast Monte Carlo (MC) simulations of proton transport have been implemented recently on GPUs. However, these usually use simplified models for non-elastic (NE) proton-nucleus interactions. Our primary goal is to build a…

Medical Physics · Physics 2015-06-11 H. Wan Chan Tseung , J. Ma , C. Beltran

There is a need to develop Monte Carlo simulations of stroke to run in-silico trials to replace animal models, explore clinical scenarios to develop hypotheses for clinical studies and for interpreting clinical monitoring. We perform…

Medical imaging phantoms are widely used for validation and verification of imaging systems and algorithms in surgical guidance and radiation oncology procedures. Especially, for the performance evaluation of new algorithms in the field of…