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The Centers for Medicare & Medicaid Services (CMS) has introduced CMS1074v2, a quality measure for computed tomography (CT) that assesses radiation dose and image quality across 18 CT exam categories. This measure mandates the calculation…

Medical Physics · Physics 2025-03-11 Gary Y Ge , Charles M Weaver , Jie Zhang

This study proposes Scout-Dose-TCM for direct, prospective estimation of organ-level doses under tube current modulation (TCM) and compares its performance to two established methods. We analyzed contrast-enhanced chest-abdomen-pelvis CT…

Triple-GEM detectors are a well known technology in high energy physics. In order to have a complete understanding of their behavior, in parallel with on beam testing, a Monte Carlo code has to be developed to simulate their response to the…

The design, construction, and preliminary testing of a second generation proton CT scanner is presented. All current treatment planning systems at proton therapy centers use X-ray CT as the primary imaging modality for treatment planning to…

Purpose: We propose a general framework for quantifying predictive uncertainties of dose-related quantities and leveraging this information in a dose mimicking problem in the context of automated radiation therapy treatment planning.…

Medical Physics · Physics 2021-09-08 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

A novel phase-space source implementation has been designed for GPU-based Monte Carlo dose calculation engines. Due to the parallelized nature of GPU hardware, it is essential to simultaneously transport particles of the same type and…

Medical Physics · Physics 2013-06-21 Reid Townson , Xun Jia , Zhen Tian , Yan Jiang Graves , Sergei Zavgorodni , Steve B Jiang

Computed tomography (CT) is a beneficial imaging tool for diagnostic purposes. CT scans provide detailed information concerning the internal anatomic structures of a patient, but present higher radiation dose and costs compared to X-ray…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Benjamin Paulson , Joshua Goldshteyn , Sydney Balboni , John Cisler , Andrew Crisler , Natalia Bukowski , Julia Kalish , Theodore Colwell

We test the feasibility of calculating proton stopping power (SP) from a set of virtual monochromatic (VM) CT images, created with Monte Carlo-generated CT scans, using a dual-energy CT-to-SP procedure. The Monte Carlo CT simulations, with…

Medical Physics · Physics 2022-06-23 Adam Zieser , Ugur Akgun , Yasar Onel

In this work, we proposed virtual imaging simulators as an alternative approach to experimental validation of beam range uncertainty in complex patient geometry using a computational model of a human head and a photon-counting CT scanner.…

Medical Physics · Physics 2026-01-05 S. Vrbaški , G. Stanić , S. Molinelli , M. Bhattarai , E. Abadi , M. Ciocca , E. Samei

Purpose: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aim to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance, and…

Medical Physics · Physics 2024-02-02 Amar Kavuri , Mini Das

The use of computed tomography (CT) imaging has become of increasing interest to academic areas outside of the field of medical imaging and industrial inspection, e.g., to biology and cultural heritage research. The pecularities of these…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Florian Schiffers , Thomas Bochynek , Andre Aichert , Tobias Würfl , Michael Rubenstein , Oliver Cossairt

We demonstrate the importance and utility of Monte Carlo simulation of single-photon detectors. Devising an optimal simulation is strongly influenced by the particular application because of the complexity of modern, avalanche-diode-based…

Quantum Physics · Physics 2014-11-14 Mario Stipčević , Daniel J. Gauthier

Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…

Purpose: The aim of this work was, a) to assess two treatment planning strategies for accounting CT-artifacts introduced by temporary tissue-expanders(TTEs); b) to evaluate the dosimetric impact of two commercially available and one novel…

Medical Physics · Physics 2023-05-08 Jose Ramos-Méndez , Catherine Park , Manju Sharma

Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…

Medical Physics · Physics 2026-02-26 Yuemeng Feng , Lisa Blackberg , Arkadiusz Sitek , Hamid Sabet

This work summarises the results of a comparison organized by EURADOS focused on the usage of the ICRP Reference Computational Phantoms. This activity aimed to provide training for the implementation of voxel phantoms in Monte Carlo…

We present a comprehensive methodology for the simulation of astronomical images from optical survey telescopes. We use a photon Monte Carlo approach to construct images by sampling photons from models of astronomical source populations,…

PET imaging is a non-invasive technique for particle range verification in proton therapy. It is based on measuring the beta+ annihilations caused by nuclear interactions of the protons in the patient. In this work we present measurements…

Monte Carlo (MC) simulations provide gold-standard accuracy for carbon ion therapy dose calculations but are computationally intensive. Analytical pencil beam algorithms offer speed but reduced accuracy in heterogeneous tissues. We…

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

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