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Improving effective treatment plans in carbon ion therapy, especially for targeting radioresistant tumors located in deep seated regions while sparing normal tissues, depends on a precise and computationally efficient dose calculation…

Medical Physics · Physics 2025-06-25 Fulya Halıcılar , Metin Arık

The use of automatic systems in the analysis of medical images has proven to be very useful to radiologists, especially in the framework of screening programs, in which radiologists make their first diagnosis on the basis of images only,…

This paper provides a fast and patient-specific scatter artifact correction method for cone-beam computed tomography (CBCT) used in image-guided interventional procedures. Due to increased irradiated volume of interest in CBCT imaging,…

Medical Physics · Physics 2015-01-20 Wei Zhao , Stephen Brunner , Kai Niu , Sebastian Schafer , Kevin Royalty , Guang-Hong Chen

Dose-finding trials are a key component of the drug development process and rely on a statistical design to help inform dosing decisions. Triallists wishing to choose a design require knowledge of operating characteristics of competing…

Computation · Statistics 2025-03-11 Michael Sweeting , Daniel Slade , Dan Jackson , Kristian Brock

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

We present a method to facilitate Monte Carlo simulations in the grand canonical ensemble given a target mean particle number. The method imposes a fictitious dynamics on the chemical potential, to be run concurrently with the Monte Carlo…

Statistical Mechanics · Physics 2022-04-27 Cole Miles , Benjamin Cohen-Stead , Owen Bradley , Steven Johnston , Richard Scalettar , Kipton Barros

In this paper we investigate, with a detailed Monte-Carlo simulation based on Geant4, the novel approach [Nucl. Instrum. Methods A588 (2008) 457] to 3D imaging with photon scattering. A monochromatic and well collimated gamma beam is used…

Medical Physics · Physics 2011-09-23 M. Lenti , M. Veltri

Monte Carlo simulations are a unique tool to check the response of a detector and to monitor its performance. For a deep-sea neutrino telescope, the variability of the environmental conditions that can affect the behaviour of the data…

High Energy Astrophysical Phenomena · Physics 2021-02-03 The ANTARES Collaboration , A. Albert , M. André , M. Anghinolfi , G. Anton , M. Ardid , J. -J. Aubert , J. Aublin , B. Baret , S. Basa , B. Belhorma , V. Bertin , S. Biagi , M. Bissinger , J. Boumaaza , M. Bouta , M. C. Bouwhuis , H. Branzas , R. Bruijn , J. Brunner , J. Busto , A. Capone , L. Caramete , J. Carr , S. Cecchini , S. Celli , M. Chabab , T. N. Chau , R. Cherkaoui El Moursli , T. Chiarusi , M. Circella , A. Coleiro , M. Colomer-Molla , R. Coniglione , P. Coyle , A. Creusot , A. F. Diaz , G. de Wasseige , A. Deschamps , C. Distefano , I. Di Palma , A. Domi , C. Donzaud , D. Dornic , D. Drouhin , T. Eberl , N. El Khayati , A. Enzenhofer , A. Ettahiri , P. Fermani , G. Ferrara , F. Filippini , L. Fusco , P. Gay , H. Glotin , R. Gozzini , K. Graf , C. Guidi , S. Hallmann , H. van Haren , A. J. Heijboer , Y. Hello , J. J. Hernandez-Rey , J. Hossl , J. Hofestadt , F. Huang , G. Illuminati , C. W. James , M. de Jong , P. de Jong , M. Jongen , M. Kadler , O. Kalekin , U. Katz , N. R. Khan-Chowdhury , A. Kouchner , I. Kreykenbohm , V. Kulikovskiy , R. Lahmann , R. Le Breton , D. Lefevre , E. Leonora , G. Levi , M. Lincetto , D. Lopez-Coto , S. Loucatos , J. Manczak , M. Marcelin , A. Margiotta , A. Marinelli , J. A. Martinez-Mora , S. Mazzou , K. Melis , P. Migliozzi , M. Moser , A. Moussa , R. Muller , L. Nauta , S. Navas , E. Nezri , A. Nunez-Castineyra , B. O'Fearraigh , M. Organokov , G. E. Pavalas , C. Pellegrino , M. Perrin-Terrin , P. Piattelli , C. Poirè , V. Popa , T. Pradier , N. Randazzo , S. Reck , G. Riccobene , F. Salesa , A. Sanchez-Losa , D. F. E. Samtleben , M. Sanguineti , P. Sapienza , J. Schnabel , F. Schussler , M. Spurio , Th. Stolarczyk , B. Strandberg , M. Taiuti , Y. Tayalati , T. Thakore , S. J. Tingay , B. Vallage , V. Van Elewyck , F. Versari , S. Viola , D. Vivolo , J. Wilms , A. Zegarelli , J. D. Zornoza , J. Zuniga

Monte Carlo methods are widely used to estimate observables in many-body quantum systems. However, conventional sampling schemes often require a large number of samples to achieve sufficient accuracy. In this work we propose the…

Quantum Physics · Physics 2026-01-29 Wenxuan Zhang , Dingzu Wang , Dario Poletti

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

The Monte Carlo (MC) simulation method is a powerful tool for radiation physicists, and several general-purpose software packages are commonly applied in a myriad of different radiation physics fields today. In medical physics, charged…

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Simulation of x-ray projection images plays an important role in cone beam CT (CBCT) related research projects. A projection image contains primary signal, scatter signal, and noise. It is computationally demanding to perform accurate and…

Medical Physics · Physics 2015-06-04 Xun Jia , Hao Yan , Laura Cervino , Michael Folkerts , Steve B. Jiang

Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…

Medical Physics · Physics 2025-02-04 S. Gros , J. Bian , J. Jackson , M. Delafuente , H. Kang , W. Small , M. Mahesh

Consider a central problem in randomized approximation schemes that use a Monte Carlo approach. Given a sequence of independent, identically distributed random variables $X_1,X_2,\ldots$ with mean $\mu$ and standard deviation at most $c…

Statistics Theory · Mathematics 2014-11-18 Mark Huber

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Dac Thai Nguyen , Trung Thanh Nguyen , Huu Tien Nguyen , Thanh Trung Nguyen , Huy Hieu Pham , Thanh Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

Particle-in-cell methods with stochastic collision models are commonly used to simulate collisional plasma dynamics, with applications ranging from hypersonic flight to semiconductor manufacturing. Code verification of such methods is…

Computational Physics · Physics 2026-05-26 Brian A. Freno , William J. McDoniel , Christopher H. Moore , Neil R. Matula

We have implemented a Monte Carlo algorithm to model and predict the response of various kinds of CCDs to X-ray photons and minimally-ionizing particles and have applied this model to the CCDs in the Chandra X-ray Observatory's Advanced CCD…

Astrophysics · Physics 2015-06-24 L. K. Townsley , P. S. Broos , G. Chartas , E. Moskalenko , J. A. Nousek , G. G. Pavlov

Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…

The current capacity of computers makes it possible to perform simulations of small systems with portable, explicit-solvent potentials achieving high degree of accuracy. However, simplified models must be employed to exploit the behaviour…

Biomolecules · Quantitative Biology 2015-06-18 R. Capelli , C. Paissoni , P. Sormanni , G. Tiana