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This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Machine learning-aided clinical decision support has the potential to significantly improve patient care. However, existing efforts in this domain for principled quantification of uncertainty have largely been limited to applications of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 L. Julian Lechuga Lopez , Tim G. J. Rudner , Farah E. Shamout

The linking of clinical entities is a crucial part of extracting structured information from clinical texts. It is the process of assigning a code from a medical ontology or classification to a phrase in the text. The International…

Computation and Language · Computer Science 2025-09-08 Sylvia Vassileva , Ivan Koychev , Svetla Boytcheva

Automatic ICD coding, the task of assigning disease and procedure codes to electronic medical records, is crucial for clinical documentation and billing. While existing methods primarily enhance model understanding of code hierarchies and…

Computation and Language · Computer Science 2025-11-11 Tuan-Dung Le , Shohreh Haddadan , Thanh Q. Thieu

Prediction of medical codes from clinical notes is both a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort spent by…

Computation and Language · Computer Science 2021-07-23 Byung-Hak Kim , Varun Ganapathi

Medical coding translates clinical documentation into standardized codes for billing, research, and public health, but manual coding is time-consuming and error-prone. Existing automation efforts rely on small datasets that poorly represent…

ICD coding is the international standard for capturing and reporting health conditions and diagnosis for revenue cycle management in healthcare. Manually assigning ICD codes is prone to human error due to the large code vocabulary and the…

Machine Learning · Computer Science 2021-03-16 Youngwoo Kim , Cheng Li , Bingyang Ye , Amir Tahmasebi , Javed Aslam

Clinicians may rely on medical coding systems such as International Classification of Diseases (ICD) to identify patients with diseases from Electronic Health Records (EHRs). However, due to the lack of detail and specificity as well as a…

Computation and Language · Computer Science 2022-05-19 Jingqing Zhang , Atri Sharma , Luis Bolanos , Tong Li , Ashwani Tanwar , Vibhor Gupta , Yike Guo

The use of International Classification of Diseases (ICD) codes in healthcare presents a challenge in selecting relevant codes as features for machine learning models due to this system's large number of codes. In this study, we compared…

Machine Learning · Computer Science 2024-10-29 Peyman Ghasemi , Joon Lee

In medicine, machine learning (ML) datasets are often built using the International Classification of Diseases (ICD) codes. As new models are being developed, there is a need for larger datasets. However, ICD codes are intended for billing.…

Machine Learning · Computer Science 2024-07-12 Abigail E. Whitlock , Gondy Leroy , Fariba M. Donovan , John N. Galgiani

Clinical text provides essential information to estimate the acuity of a patient during hospital stays in addition to structured clinical data. In this study, we explore how clinical text can complement a clinical predictive learning task.…

Machine Learning (ML) is widely used to automatically extract meaningful information from Electronic Health Records (EHR) to support operational, clinical, and financial decision-making. However, ML models require a large number of…

Machine Learning · Computer Science 2021-04-14 Martha Dais Ferreira , Michal Malyska , Nicola Sahar , Riccardo Miotto , Fernando Paulovich , Evangelos Milios

The task of assigning diagnostic ICD codes to patient hospital admissions is typically performed by expert human coders. Efforts towards automated ICD coding are dominated by supervised deep learning models. However, difficulties in…

Artificial Intelligence · Computer Science 2023-11-14 Joseph S. Boyle , Antanas Kascenas , Pat Lok , Maria Liakata , Alison Q. O'Neil

Medical coding translates professionally written medical reports into standardized codes, which is an essential part of medical information systems and health insurance reimbursement. Manual coding by trained human coders is time-consuming…

Computation and Language · Computer Science 2021-09-27 Wei Sun , Shaoxiong Ji , Erik Cambria , Pekka Marttinen

Predicting in-hospital mortality for intensive care unit (ICU) patients is key to final clinical outcomes. AI has shown advantaged accuracy but suffers from the lack of explainability. To address this issue, this paper proposes an…

Machine Learning · Computer Science 2024-01-01 Xingqiao Li , Jindong Gu , Zhiyong Wang , Yancheng Yuan , Bo Du , Fengxiang He

Characterization of a patient clinical phenotype is central to biomedical informatics. ICD codes, assigned to inpatient encounters by coders, is important for population health and cohort discovery when clinical information is limited.…

Automatically associating ICD codes with electronic health data is a well-known NLP task in medical research. NLP has evolved significantly in recent years with the emergence of pre-trained language models based on Transformers…

Computation and Language · Computer Science 2023-04-07 Yakini Tchouka , Jean-François Couchot , David Laiymani , Philippe Selles , Azzedine Rahmani

In the context of the Electronic Health Record, automated diagnosis coding of patient notes is a useful task, but a challenging one due to the large number of codes and the length of patient notes. We investigate four models for assigning…

Computation and Language · Computer Science 2017-11-22 Tal Baumel , Jumana Nassour-Kassis , Raphael Cohen , Michael Elhadad , No`emie Elhadad

International Classification of Diseases (ICD) is a set of classification codes for medical records. Automated ICD coding, which assigns unique International Classification of Diseases codes with each medical record, is widely used recently…

Artificial Intelligence · Computer Science 2022-12-12 Shi Wang , Daniel Tang , Luchen Zhang , Huilin Li , Ding Han

The clinical notes are usually typed into the system by physicians. They are typically required to be marked by standard medical codes, and each code represents a diagnosis or medical treatment procedure. Annotating these notes is time…

Machine Learning · Computer Science 2023-05-10 Guodong Liu