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Multimodal Machine Learning offers a holistic view of a patient's status, integrating structured and unstructured data from electronic health records (EHR). We propose a framework to predict metastasis risk one month prior to diagnosis,…

Machine Learning · Computer Science 2026-04-01 Franco Rugolon , Korbinian Randl , Braslav Jovanovic , Ioanna Miliou , Panagiotis Papapetrou

Medical imaging classifiers can achieve high predictive accuracy, but quantifying their uncertainty remains an unresolved challenge, which prevents their deployment in medical clinics. We present an algorithm that can modify any classifier…

Machine Learning · Computer Science 2024-08-12 Roy Hirsch , Jacob Goldberger

Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

Machine Learning · Computer Science 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

Computation and Language · Computer Science 2021-02-09 Betty van Aken , Jens-Michalis Papaioannou , Manuel Mayrdorfer , Klemens Budde , Felix A. Gers , Alexander Löser

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Image-based single-modality compression learning approaches have demonstrated exceptionally powerful encoding and decoding capabilities in the past few years , but suffer from blur and severe semantics loss at extremely low bitrates. To…

Image and Video Processing · Electrical Eng. & Systems 2023-04-27 Xuhao Jiang , Weimin Tan , Tian Tan , Bo Yan , Liquan Shen

Large-scale EHR prediction across institutions is hindered by substantial heterogeneity in schemas and code systems. Although Common Data Models (CDMs) can standardize records for multi-institutional learning, the manual harmonization and…

Computation and Language · Computer Science 2026-04-02 Kyunghoon Hur , Heeyoung Kwak , Jinsu Jang , Nakhwan Kim , Edward Choi

Medical image segmentation is a fundamental yet challenging task due to the arduous process of acquiring large volumes of high-quality labeled data from experts. Contrastive learning offers a promising but still problematic solution to this…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Shuang Zeng , Lei Zhu , Xinliang Zhang , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Qian Chen , Hangzhou He , Lujia Jin , Zifeng Tian , Qiushi Ren , Zhaoheng Xie , Yanye Lu

Mortality prediction in intensive care units is considered one of the critical steps for efficiently treating patients in serious condition. As a result, various prediction models have been developed to address this problem based on modern…

Machine Learning · Computer Science 2020-12-15 Huachuan Wang , Yuanfei Bi

As clinical data are becoming increasingly available, machine learning methods have been employed to extract knowledge from them and predict clinical events. While promising, approaches suffer from at least two main issues: low availability…

As artificial intelligence systems move toward clinical deployment, ensuring reliable prediction behavior is fundamental for safety-critical decision-making tasks. One proposed safeguard is selective prediction, where models can defer…

Machine Learning · Computer Science 2026-05-25 L. Julián Lechuga López , Farah E. Shamout , Tim G. J. Rudner

International Classification of Diseases (ICD) coding assigns diagnosis codes to clinical documents and is essential for healthcare billing and clinical analysis. Reliable coding requires that each predicted code be supported by explicit…

Computation and Language · Computer Science 2026-05-08 Xu Zhang , Wenxin Ma , Chenxu Wu , Rongsheng Wang , Zhiyang He , Xiaodong Tao , Kun Zhang , S. Kevin Zhou

Conventional deep learning models deal with images one-by-one, requiring costly and time-consuming expert labeling in the field of medical imaging, and domain-specific restriction limits model generalizability. Visual in-context learning…

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single…

Machine Learning · Computer Science 2025-05-13 Fergus Imrie , Stefan Denner , Lucas S. Brunschwig , Klaus Maier-Hein , Mihaela van der Schaar

The inherent multimodality and heterogeneous temporal structures of medical data pose significant challenges for modeling. We propose MedM2T, a time-aware multimodal framework designed to address these complexities. MedM2T integrates: (i)…

Machine Learning · Computer Science 2026-03-26 Yu-Chen Kuo , Yi-Ju Tseng

Recent advances in multimodal large language models have enabled unified processing of visual and textual inputs, offering promising applications in general-purpose medical AI. However, their ability to generalize compositionally across…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Pooja Singh , Siddhant Ujjain , Tapan Kumar Gandhi , Sandeep Kumar

In order to submit a claim to insurance companies, a doctor needs to code a patient encounter with both the diagnosis (ICDs) and procedures performed (CPTs) in an Electronic Health Record (EHR). Identifying and applying relevant procedures…

Machine Learning · Statistics 2021-12-30 Hasham Ul Haq , Rameel Ahmad , Sibt Ul Hussain

Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…

Quantitative Methods · Quantitative Biology 2025-12-11 Noor Ul Huda Shah , Tanveer Hussain , Amr Ahmed , Yonghuai Liu , Usman Ali , Ardhendu Behera

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

Machine Learning · Computer Science 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu

Addressing the challenge of multimodal data fusion in high-dimensional biomedical informatics, we propose MMCTOP, a MultiModal Clinical-Trial Outcome Prediction framework that integrates heterogeneous biomedical signals spanning (i)…

Machine Learning · Computer Science 2025-12-29 Carolina Aparício , Qi Shi , Bo Wen , Tesfaye Yadete , Qiwei Han
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