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Purpose: The mechanics of the mitral valve leaflet as a nonlinear, inelastic and anisotropic soft tissue results from an integrated response of many mathematical/physical indexes' that illustrate the tissue. In the past decade, finite…

Medical Physics · Physics 2015-06-24 Mersedeh Karvandi , Saeed Ranjbar , Seyed Ahmad Hassantash , Mahnoosh Foroughi

Viscous flow past a finite flat plate moving in direction normal to itself is studied numerically.The plate moves with velocity $at^p$, where $p=0,0.5,1,2$. We present the evolution of vorticity profiles, streaklines and streamlines, and…

Fluid Dynamics · Physics 2015-06-19 Ling Xu , Monika Nitsche

Fluid-structure interaction in the developing heart is an active area of research in developmental biology. However, investigation of heart dynamics is mostly limited to computational fluid dynamics simulations using heart wall structure…

Quantitative Methods · Quantitative Biology 2018-03-01 Vytautas Zickus , Jonathan M. Taylor

The liver has a unique blood supply system and plays an important role in the human blood circulatory system. Thus, hemodynamic problems related to the liver serve as an important part in clinical diagnosis and treatment. Although…

Numerical Analysis · Mathematics 2021-10-15 Ting Wu , Keqin Liu , Emily Fainman , Ying Wang

Accurate three-dimensional (3D) reconstruction of cardiac chamber motion from time-resolved medical imaging modalities is of growing interest in both the clinical and biomechanical fields. Despite recent advancement, the cardiac motion…

Medical Physics · Physics 2025-04-18 Francesco Capuano , Yue-Hin Loke , Ibrahim Yildiran , Laura Olivieri , Elias Balaras

Ejection fraction (EF) is commonly measured by echocardiography, by dividing the volume ejected by the heart (stroke volume) by the volume of the filled heart (end-diastolic volume). Utilizing volume changes of left myocardial segments per…

Medical Physics · Physics 2018-03-09 Mersedeh Karvandi , Saeed Ranjbar

Four-dimensional (4D) left ventricular myocardial velocity mapping (MVM) is a cardiac magnetic resonance (CMR) technique that allows assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Yinzhe Wu , Suzan Hatipoglu , Diego Alonso-Álvarez , Peter Gatehouse , David Firmin , Jennifer Keegan , Guang Yang

Internal haemorrhage, often leading to cardio-vascular arrest happens to be one of the prime sources of high fatality rates in mammals. We propose a simplistic model of fluid flow to specify the location of the haemorrhagic spots, which, if…

Soft Condensed Matter · Physics 2013-04-01 Amit K. Chattopadhyay , Shreekantha Sil

The meniscal tissue is a layered material with varying properties influenced by collagen content and arrangement. Understanding the relationship between structure and properties is crucial for disease management, treatment development, and…

Computational Engineering, Finance, and Science · Computer Science 2023-07-26 J. Waghorne , F. P. Bonomo , A. Rabbani , D. Bell , O. Barrera

This Artificial left ventricle is based on a simple conic assumption shape for left ventricle where its motion is made by attached compressed elastic tubes to its walls which are regarded to electrical points at each nodal .This compressed…

Medical Physics · Physics 2014-08-05 Saeed Ranjbar , Tohid Emami Meybodi , Mahmood Emami Meybodi

Vesicles are becoming a quite popular model for the study of red blood cells (RBCs). This is a free boundary problem which is rather difficult to handle theoretically. Quantitative computational approaches constitute also a challenge. In…

Soft Condensed Matter · Physics 2015-05-14 Alexander Farutin , Thierry Biben , Chaouqi Misbah

Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…

Computational Physics · Physics 2008-02-19 Renat A. Sultanov , Dennis Guster , Brent Engelbrekt , Richard Blankenbecler

Fluidic transport in inverted T-shaped cavities with the flow entering through the top and exiting from the two bottom outlets experiences an interesting phenomenon that causes particles having density lower than that of the fluid medium to…

Fluid Dynamics · Physics 2022-11-15 Sneham Das , Saikat Basu

Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…

Quantitative Methods · Quantitative Biology 2020-02-21 Megan J. Chambers , Mitchel J. Colebank , M Umar Qureshi , Rachel Clipp , Mette S. Olufsen

We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in…

We propose the Vortex Particle Flow Map (VPFM) method to simulate incompressible flow with complex vortical evolution in the presence of dynamic solid boundaries. The core insight of our approach is that vorticity is an ideal quantity for…

Graphics · Computer Science 2025-05-29 Sinan Wang , Junwei Zhou , Fan Feng , Zhiqi Li , Yuchen Sun , Duowen Chen , Greg Turk , Bo Zhu

The limitations of conventional imaging techniques have hitherto precluded a thorough and formal investigation of the complex morphology of the left ventricular (LV) endocardial surface and its relation to the severity of Coronary Artery…

Computer Vision and Pattern Recognition · Computer Science 2013-02-14 Anirban Mukhopadhyay , Zhen Qian , Suchendra M. Bhandarkar , Tianming Liu , Sarah Rinehart , Szilard Voros

The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization Microscopy (DULM) has allowed for the quantitative mapping of the…

We present a Lagrangian analysis of turbulent blood flow in the human left heart using high-fidelity simulations based on a patient-specific anatomical model. Leveraging a fully coupled fluid-structure-electrophysiology interaction (FSEI)…

Fluid Dynamics · Physics 2025-06-13 Fabio Guglietta , Martino Andrea Scarpolini , Francesco Viola , Luca Biferale

Quantitative assessment of left ventricle (LV) function from cine MRI has significant diagnostic and prognostic value for cardiovascular disease patients. The temporal movement of LV provides essential information on the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Wenjun Yan , Yuanyuan Wang , Zeju Li , Rob J. van der Geest , Qian Tao
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