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The invasive measurement of the hepatic venous pressure gradient is still considered as the reference method to assess the severity of portal hypertension. Even though previous studies have shown that the liver stiffness measured by…

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

The leading edge vortex (LEV) is one of the most important lift augmentation mechanisms in flapping wing aerodynamics. We propose a methodology that aims to provide a quantitative description of the LEV. The first step of the method…

Fluid Dynamics · Physics 2025-09-08 Alejandro Gonzalo , Manuel Garcia-Villalba , Oscar Flores

The coherent vortical structures in turbulent flow through a strong 16:1 3-D contraction, are studied using time-resolved volumetric measurements. Visualization using vorticity magnitude criterion shows the emergence of long, stretched…

Accurate assessment of intraventricular blood flow is essential for evaluating hemodynamic conditions in patients supported by Left Ventricular Assist Devices (LVADs). However, clinical imaging is either incompatible with LVADs or yields…

Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…

4D-flow magnetic resonance imaging (MRI) is an emerging imaging technique where spatiotemporal 3D blood velocity can be captured with full volumetric coverage in a single non-invasive examination. This enables qualitative and quantitative…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Edward Ferdian , Avan Suinesiaputra , David Dubowitz , Debbie Zhao , Alan Wang , Brett Cowan , Alistair Young

A method is presented for the registration of MRA and 4D Flow images, with the goal of calculating blood flow properties using both modalities simultaneously. In particular, the method produces an alignment of segmentations of vessel…

Quantitative Methods · Quantitative Biology 2025-04-28 Dan Lior , Craig G. Rusin , Justin Weigand , Kristina V. Montez , Yimo Wang , Silvana Molossi , Daniel J. Penny , Charles Puelz

We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…

Fluid Dynamics · Physics 2022-10-06 Mattia Corti , Alberto Zingaro , Luca Dede' , Alfio Maria Quarteroni

Measurement techniques such as Magnetic Resonance Velocimety (MRV) and Magnetic Resonance Concentration (MRC) are useful for obtaining 3D time-averaged flow quantities in complex turbulent flows, but cannot measure turbulent correlations or…

Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…

Fluid Dynamics · Physics 2021-06-15 Giulia Bertaglia , Valerio Caleffi , Alessandro Valiani

Three-dimensional (3D) instabilities on a (potentially turbulent) two-dimensional (2D) flow are still incompletely understood, despite recent progress. Here, based on known physical properties of such 3-D instabilities, we propose a simple,…

Fluid Dynamics · Physics 2021-05-19 Adrian van Kan , Alexandros Alexakis , Marc Etienne Brachet

A blood turbine-pump system (iATVA), resembling a turbocharger was proposed as a mechanical right-heart assist device without external drive power. In this study, the iATVA system is investigated with particular emphasis on the blood…

Fluid Dynamics · Physics 2024-04-17 Kagan Ucak , Faruk Karatas , Emre Cetinkaya , Kerem Pekkan

Deviation of blood flow from an optimal range is known to be associated with the initiation and progression of vascular pathologies. Important open questions remain about how the abnormal flow drives specific wall changes in pathologies…

Left ventricular diastolic dysfunction (LVDD) is a group of diseases that adversely affect the passive phase of the cardiac cycle and can lead to heart failure. While left ventricular end-diastolic pressure (LVEDP) is a valuable prognostic…

Tissues and Organs · Quantitative Biology 2025-01-23 Emilio A. Mendiola , Raza Rana Mehdi , Dipan J. Shah , Reza Avazmohammadi

Echocardiography (echo) is an indispensable tool in a cardiologist's diagnostic armamentarium. To date, almost all echocardiographic parameters require time-consuming manual labeling and measurements by an experienced echocardiographer and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-26 Mohamed Y. Elwazir , Zeynettin Akkus , Didem Oguz , Jae K. Oh

The paper deals with modeling the liver perfusion intended to improve quantitative analysis of the tissue scans provided by the contrast-enhanced computed tomography (CT). For this purpose, we developed a model of dynamic transport of the…

Computational Engineering, Finance, and Science · Computer Science 2018-08-01 Eduard Rohan , Vladimír Lukeš , Alena Jonášová

We introduce a new method, (Doppler Velocity Reconstruction or DoVeR), for reconstructing two-component velocity fields from color Doppler scans. DoVeR employs the streamfunction-vorticity equation, which satisfies mass conservation while…

Medical Physics · Physics 2020-10-23 Brett A Meyers , Craig J Goergen , Patrick Segers , Pavlos P Vlachos

Ventricular Fibrillation (VF) is a malignant cardiac arrhythmia and the leading cause of sudden cardiac death, characterized by disorganized, high-frequency ventricular activity that results in the rapid loss of coordinated pump function…

Biological Physics · Physics 2025-11-04 Artemii Remizov , Sergey Lapin

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…