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Many tissues take the form of thin sheets, being only a single cell thick, but millions of cells wide. These tissue sheets can bend and buckle in the third dimension. In this work, we investigated the growth and shrinkage of suspended and…

Biological Physics · Physics 2024-11-01 Hiroshi Noguchi , Jens Elgeti

A key factor influencing a drug's efficacy is its residence time in the binding pocket of the host protein. Using atomistic computer simulation to predict this residence time and the associated dissociation process is a desirable but…

Soft Condensed Matter · Physics 2015-10-08 Pratyush Tiwary , Jagannath Mondal , Joseph A. Morrone , B. J. Berne

Obstructions influence the growth and expansion of bodies in a wide range of settings -- but isolating and understanding their impact can be difficult in complex environments. Here, we study obstructed growth/expansion in a model system…

Soft Condensed Matter · Physics 2024-01-24 Abigail Plummer , Caroline Adkins , Jean-François Louf , Andrej Košmrlj , Sujit S. Datta

The stability of high-speed liquid jets is crucial for applications ranging from precision printing to needle-free drug delivery, yet it is fundamentally limited by capillary-driven breakup. A common strategy to stabilize jets is to use…

Understanding how cells escape from embedded spheroids requires a mechanical framework linking stress generation within cells, across cells, and between cells and the surrounding extracellular matrix (ECM). We develop such a framework by…

A recent experimental study showed that an induced folded flap of graphene can spontaneously drive itself its tearing and peeling off a substrate, thus producing long, micrometer sized, regular trapezoidal-shaped folded graphene…

Materials Science · Physics 2018-08-28 Alexandre F. Fonseca , Douglas S. Galvao

Exploiting the "natural" frame of space curves, we formulate an intrinsic dynamics of twisted elastic filaments in viscous fluids. A pair of coupled nonlinear equations describing the temporal evolution of the filament's complex curvature…

Soft Condensed Matter · Physics 2009-10-31 Raymond E. Goldstein , Thomas R. Powers , Chris H. Wiggins

We study the dynamics of sail membranes during a tacking maneuver, when the sail angle of attack is reversed in order to sail upwind. In successful tacking the sail flips to the mirror-image shape, while in unsuccessful tacking the sail…

Fluid Dynamics · Physics 2024-10-08 Christiana Mavroyiakoumou , Silas Alben

Widespread processes in nature and technology are governed by the dynamical transition whereby a material in an initially solid-like state then yields plastically. Major unresolved questions concern whether any material will yield smoothly…

Statistical Mechanics · Physics 2022-11-23 Joseph Pollard , Suzanne M Fielding

We present an analytical theory for heteropolymer deformation, as exemplified experimentally by stretching of single protein molecules. Using a mean-field replica theory, we determine phase diagrams for stress-induced unfolding of typical…

Statistical Mechanics · Physics 2009-11-07 Phillip L. Geissler , Eugene I. Shakhnovich

Several meters below the coastal ocean surface there are areas of high ecological activity that contain thin layers of concentrated motile phytoplankton. Gyrotactic trapping has been proposed as a potential mechanism for layer formation of…

Fluid Dynamics · Physics 2019-05-22 Smitha Maretvadakethope , Eric E. Keaveny , Yongyun Hwang

The jellyfish Clytia hemisphaerica possesses astounding regenerative capacities and is able to close even large wounds within a few hours. This rapid pace of wound closure raises the question whether tissue mechanics, rather than tissue…

Biological Physics · Physics 2026-05-21 Anne Materne , Zhiqi Shen , Chiara Sinigaglia , Carl D. Modes

The hydration process of multi-stacked phospholipid bilayers to form giant vesicles was investigated by time-resolved small angle X-ray scattering. The hydration of lipids in the liquid-crystalline phase was found to proceed in two stages.…

Chemical Physics · Physics 2007-05-23 M. Hishida , H. Seto , N. L. Yamada , K. Yoshikawa

Adhesive interactions between elastic structures such as graphene sheets, carbon nanotubes, and microtubules have been shown to exhibit hysteresis due to irrecoverable energy loss associated with bond breakage, even in static…

Biological Physics · Physics 2021-02-02 Edvin Memet , Feodor Hilitski , Zvonimir Dogic , L. Mahadevan

A mean-field kinetic model suggests that the relaxation dynamics of wormlike micellar networks is a long and complex process due to the problem of reducing the number of free end-caps (or dangling ends) while also reaching an equilibrium…

Soft Condensed Matter · Physics 2021-12-21 Marco Baiesi , Stefano Iubini , Enzo Orlandini

We model the nonlinear response of a lubricated contact composed of a two-dimensional lipid membrane immersed in a simple fluid between two parallel flat and porous walls under shear. The nonlinear dynamics of the membrane gives rise to a…

Soft Condensed Matter · Physics 2021-06-11 Thomas Le Goff , Tung B. T. To , Olivier Pierre-Louis

Hydrogel consists of a crosslinked polymer matrix imbibed with a solvent such as water at volume fractions that can exceed 90\%. They are important in many scientific and engineering applications due to their tunable physiochemical…

Soft Condensed Matter · Physics 2020-06-11 Nicholas L. Cuccia , Suraj Pothineni , Brady Wu , Joshua Méndez-Harper , Justin C. Burton

A theoretical model for stratified epithelium is presented. The viscoelastic properties of the tissue is assumed to be dependent on the spatial distribution of proliferative and differentiated cells. Based on this assumption, a hydrodynamic…

Biological Physics · Physics 2016-06-08 Wei-Ting Yeh , Hsuan-Yi Chen

We propose a nonlinear extension of the standard tube model for semidilute solutions of freely-sliding semiflexible polymers. Non-affine filament deformations at the entanglement scale, the renormalisation of direct interactions by thermal…

Soft Condensed Matter · Physics 2008-10-01 Pablo Fernandez , Steffen Grosser , Klaus Kroy

The flow in a Hele-Shaw cell with a time-increasing gap poses a unique shrinking interface problem. When the upper plate of the cell is lifted perpendicularly at a prescribed speed, the exterior less viscous fluid penetrates the interior…

Fluid Dynamics · Physics 2021-01-20 Meng Zhao , Zahra Niroobakhsh , John Lowengrub , Shuwang Li
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